Detalhe da pesquisa
1.
Cardiovascular function in nonclinical drug safety assessment: current issues and opportunities.
Int J Toxicol
; 30(3): 272-86, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21527643
2.
Standing on the shoulders of giants: Dean Franklin and his remarkable contributions to physiological measurements in animals.
Adv Physiol Educ
; 33(3): 144-56, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19745039
3.
Technological Advances in Cardiovascular Safety Assessment Decrease Preclinical Animal Use and Improve Clinical Relevance.
ILAR J
; 57(2): 120-132, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28053066
4.
The evaluation of drug-induced changes in cardiac inotropy in dogs: Results from a HESI-sponsored consortium.
J Pharmacol Toxicol Methods
; 75: 70-90, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25843226
5.
Statistical power analysis for hemodynamic cardiovascular safety pharmacology studies in beagle dogs.
J Pharmacol Toxicol Methods
; 50(2): 121-30, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15385086
6.
Cardiovascular pressure measurement in safety assessment studies: technology requirements and potential errors.
J Pharmacol Toxicol Methods
; 70(3): 210-23, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24933393
7.
A public-private consortium advances cardiac safety evaluation: achievements of the HESI Cardiac Safety Technical Committee.
J Pharmacol Toxicol Methods
; 68(1): 7-12, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23567075
8.
Left ventricular pressure, contractility and dP/dt(max) in nonclinical drug safety assessment studies.
J Pharmacol Toxicol Methods
; 66(2): 71-8, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22659561
9.
Sensitivity of two noninvasive blood pressure measurement techniques compared to telemetry in cynomolgus monkeys and beagle dogs.
J Pharmacol Toxicol Methods
; 62(1): 54-63, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20435151
10.
Evaluation of blood pressure measurement using a miniature blood pressure transmitter with jacketed external telemetry in cynomolgus monkeys.
J Pharmacol Toxicol Methods
; 62(2): 127-35, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20558308
11.
Left thoracotomy surgical approach for chronic instrumentation in dogs and monkeys providing high-quality electrocardiogram signals.
J Pharmacol Toxicol Methods
; 62(2): 136-42, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20550968
12.
Effects of antipsychotic drugs on I(to), I (Na), I (sus), I (K1), and hERG: QT prolongation, structure activity relationship, and network analysis.
Pharm Res
; 23(6): 1133-43, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16715368
13.
Three-dimensional quantitative structure-activity relationship for inhibition of human ether-a-go-go-related gene potassium channel.
J Pharmacol Exp Ther
; 301(2): 427-34, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-11961040