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Nucleic Acids Res ; 45(D1): D985-D994, 2017 01 04.
Artigo em Inglês | MEDLINE | ID: mdl-27899665

RESUMO

We have designed and developed a data integration and visualization platform that provides evidence about the association of known and potential drug targets with diseases. The platform is designed to support identification and prioritization of biological targets for follow-up. Each drug target is linked to a disease using integrated genome-wide data from a broad range of data sources. The platform provides either a target-centric workflow to identify diseases that may be associated with a specific target, or a disease-centric workflow to identify targets that may be associated with a specific disease. Users can easily transition between these target- and disease-centric workflows. The Open Targets Validation Platform is accessible at https://www.targetvalidation.org.


Assuntos
Biologia Computacional/métodos , Terapia de Alvo Molecular , Ferramenta de Busca , Software , Bases de Dados Factuais , Humanos , Terapia de Alvo Molecular/métodos , Reprodutibilidade dos Testes , Navegador , Fluxo de Trabalho
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