Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Non-mendelian Inheritance in Mammals Is Highly Constrained.

Isbel, Luke; Schübeler, Dirk.

Cell ; 175(5): 1179-1181, 2018 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-30445037

2.

Cooperation between bHLH transcription factors and histones for DNA access.

Michael, Alicia K; Stoos, Lisa; Crosby, Priya; Eggers, Nikolas; Nie, Xinyu Y; Makasheva, Kristina; Minnich, Martina; Healy, Kelly L; Weiss, Joscha; Kempf, Georg; Cavadini, Simone; Kater, Lukas; Seebacher, Jan; Vecchia, Luca; Chakraborty, Deyasini; Isbel, Luke; Grand, Ralph S; Andersch, Florian; Fribourgh, Jennifer L; Schübeler, Dirk; Zuber, Johannes; Liu, Andrew C; Becker, Peter B; Fierz, Beat; Partch, Carrie L; Menet, Jerome S; Thomä, Nicolas H.

Nature ; 619(7969): 385-393, 2023 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-37407816

3.

Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo.

Sönmezer, Can; Kleinendorst, Rozemarijn; Imanci, Dilek; Barzaghi, Guido; Villacorta, Laura; Schübeler, Dirk; Benes, Vladimir; Molina, Nacho; Krebs, Arnaud Regis.

Mol Cell ; 81(2): 255-267.e6, 2021 01 21.

Artigo em Inglês | MEDLINE | ID: mdl-33290745

4.

Generating specificity in genome regulation through transcription factor sensitivity to chromatin.

Isbel, Luke; Grand, Ralph S; Schübeler, Dirk.

Nat Rev Genet ; 23(12): 728-740, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-35831531

5.

Methylation-dependent and -independent genomic targeting principles of the MBD protein family.

Baubec, Tuncay; Ivánek, Robert; Lienert, Florian; Schübeler, Dirk.

Cell ; 153(2): 480-92, 2013 Apr 11.

Artigo em Inglês | MEDLINE | ID: mdl-23582333

6.

BANP opens chromatin and activates CpG-island-regulated genes.

Grand, Ralph S; Burger, Lukas; Gräwe, Cathrin; Michael, Alicia K; Isbel, Luke; Hess, Daniel; Hoerner, Leslie; Iesmantavicius, Vytautas; Durdu, Sevi; Pregnolato, Marco; Krebs, Arnaud R; Smallwood, Sébastien A; Thomä, Nicolas; Vermeulen, Michiel; Schübeler, Dirk.

Nature ; 596(7870): 133-137, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34234345

7.

Pioneering Activity of the C-Terminal Domain of EBF1 Shapes the Chromatin Landscape for B Cell Programming.

Boller, Sören; Ramamoorthy, Senthilkumar; Akbas, Duygu; Nechanitzky, Robert; Burger, Lukas; Murr, Rabih; Schübeler, Dirk; Grosschedl, Rudolf.

Immunity ; 44(3): 527-541, 2016 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-26982363

8.

Chromatin in multicolor.

Schübeler, Dirk.

Cell ; 143(2): 183-4, 2010 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-20946976

9.

Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs.

Krol, Jacek; Busskamp, Volker; Markiewicz, Ilona; Stadler, Michael B; Ribi, Sebastian; Richter, Jens; Duebel, Jens; Bicker, Silvia; Fehling, Hans Jörg; Schübeler, Dirk; Oertner, Thomas G; Schratt, Gerhard; Bibel, Miriam; Roska, Botond; Filipowicz, Witold.

Cell ; 141(4): 618-31, 2010 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-20478254

10.

Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors.

Barisic, Darko; Stadler, Michael B; Iurlaro, Mario; Schübeler, Dirk.

Nature ; 569(7754): 136-140, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30996347

11.

Publisher Correction: DNA damage detection in nucleosomes involves DNA register shifting.

Matsumoto, Syota; Cavadini, Simone; Bunker, Richard D; Grand, Ralph S; Potenza, Alessandro; Rabl, Julius; Yamamoto, Junpei; Schenk, Andreas D; Schübeler, Dirk; Iwai, Shigenori; Sugasawa, Kaoru; Kurumizaka, Hitoshi; Thomä, Nicolas H.

Nature ; 571(7764): E6, 2019 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-31239520

12.

DNA damage detection in nucleosomes involves DNA register shifting.

Matsumoto, Syota; Cavadini, Simone; Bunker, Richard D; Grand, Ralph S; Potenza, Alessandro; Rabl, Julius; Yamamoto, Junpei; Schenk, Andreas D; Schübeler, Dirk; Iwai, Shigenori; Sugasawa, Kaoru; Kurumizaka, Hitoshi; Thomä, Nicolas H.

Nature ; 571(7763): 79-84, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31142837

13.

Genome-wide Single-Molecule Footprinting Reveals High RNA Polymerase II Turnover at Paused Promoters.

Krebs, Arnaud R; Imanci, Dilek; Hoerner, Leslie; Gaidatzis, Dimos; Burger, Lukas; Schübeler, Dirk.

Mol Cell ; 67(3): 411-422.e4, 2017 Aug 03.

Artigo em Inglês | MEDLINE | ID: mdl-28735898

14.

monaLisa: an R/Bioconductor package for identifying regulatory motifs.

Machlab, Dania; Burger, Lukas; Soneson, Charlotte; Rijli, Filippo M; Schübeler, Dirk; Stadler, Michael B.

Bioinformatics ; 38(9): 2624-2625, 2022 04 28.

Artigo em Inglês | MEDLINE | ID: mdl-35199152

15.

CG dinucleotides enhance promoter activity independent of DNA methylation.

Hartl, Dominik; Krebs, Arnaud R; Grand, Ralph S; Baubec, Tuncay; Isbel, Luke; Wirbelauer, Christiane; Burger, Lukas; Schübeler, Dirk.

Genome Res ; 29(4): 554-563, 2019 04.

Artigo em Inglês | MEDLINE | ID: mdl-30709850

16.

DNA methylation is required for the control of stem cell differentiation in the small intestine.

Sheaffer, Karyn L; Kim, Rinho; Aoki, Reina; Elliott, Ellen N; Schug, Jonathan; Burger, Lukas; Schübeler, Dirk; Kaestner, Klaus H.

Genes Dev ; 28(6): 652-64, 2014 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-24637118

17.

Function and information content of DNA methylation.

Schübeler, Dirk.

Nature ; 517(7534): 321-6, 2015 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-25592537

18.

Competition between DNA methylation and transcription factors determines binding of NRF1.

Domcke, Silvia; Bardet, Anaïs Flore; Adrian Ginno, Paul; Hartl, Dominik; Burger, Lukas; Schübeler, Dirk.

Nature ; 528(7583): 575-9, 2015 Dec 24.

Artigo em Inglês | MEDLINE | ID: mdl-26675734

19.

Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation.

Baubec, Tuncay; Colombo, Daniele F; Wirbelauer, Christiane; Schmidt, Juliane; Burger, Lukas; Krebs, Arnaud R; Akalin, Altuna; Schübeler, Dirk.

Nature ; 520(7546): 243-7, 2015 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-25607372

20.

Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content.

Colombo, Daniele F; Burger, Lukas; Baubec, Tuncay; Schübeler, Dirk.

PLoS Genet ; 13(12): e1007102, 2017 12.

Artigo em Inglês | MEDLINE | ID: mdl-29267285

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