Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Changes in neuronal dopamine homeostasis following 1-methyl-4-phenylpyridinium (MPP+) exposure.

Choi, Se Joon; Panhelainen, Anne; Schmitz, Yvonne; Larsen, Kristin E; Kanter, Ellen; Wu, Min; Sulzer, David; Mosharov, Eugene V.

J Biol Chem ; 290(11): 6799-809, 2015 Mar 13.

Artigo em Inglês | MEDLINE | ID: mdl-25596531

2.

Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease.

Schmidt, Vanessa; Baum, Katharina; Lao, Angelyn; Rateitschak, Katja; Schmitz, Yvonne; Teichmann, Anke; Wiesner, Burkhard; Petersen, Claus Munck; Nykjaer, Anders; Wolf, Jana; Wolkenhauer, Olaf; Willnow, Thomas E.

EMBO J ; 31(1): 187-200, 2012 Jan 04.

Artigo em Inglês | MEDLINE | ID: mdl-21989385

3.

Glycine transporter-1 inhibition promotes striatal axon sprouting via NMDA receptors in dopamine neurons.

Schmitz, Yvonne; Castagna, Candace; Mrejeru, Ana; Lizardi-Ortiz, José E; Klein, Zoe; Lindsley, Craig W; Sulzer, David.

J Neurosci ; 33(42): 16778-89, 2013 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-24133278

4.

Parkinson's disease: return of an old prime suspect.

Sulzer, David; Schmitz, Yvonne.

Neuron ; 55(1): 8-10, 2007 Jul 05.

Artigo em Inglês | MEDLINE | ID: mdl-17610813

5.

Nucleo-cytoplasmic shuttling of APC can maximize ß-catenin/TCF concentration.

Schmitz, Yvonne; Wolkenhauer, Olaf; Rateitschak, Katja.

J Theor Biol ; 279(1): 132-42, 2011 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-21439299

6.

Glutamate controls growth rate and branching of dopaminergic axons.

Schmitz, Yvonne; Luccarelli, James; Kim, Minji; Wang, Mi; Sulzer, David.

J Neurosci ; 29(38): 11973-81, 2009 Sep 23.

Artigo em Inglês | MEDLINE | ID: mdl-19776283

7.

Heterosynaptic dopamine neurotransmission selects sets of corticostriatal terminals.

Bamford, Nigel S; Zhang, Hui; Schmitz, Yvonne; Wu, Nan-Ping; Cepeda, Carlos; Levine, Michael S; Schmauss, Claudia; Zakharenko, Stanislav S; Zablow, Leonard; Sulzer, David.

Neuron ; 42(4): 653-63, 2004 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-15157425

8.

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis.

Larsen, Kristin E; Schmitz, Yvonne; Troyer, Matthew D; Mosharov, Eugene; Dietrich, Paula; Quazi, Abrar Z; Savalle, Magali; Nemani, Venu; Chaudhry, Farrukh A; Edwards, Robert H; Stefanis, Leonidas; Sulzer, David.

J Neurosci ; 26(46): 11915-22, 2006 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-17108165

9.

Neuroprotection and neurorestoration as experimental therapeutics for Parkinson's disease.

Francardo, Veronica; Schmitz, Yvonne; Sulzer, David; Cenci, M Angela.

Exp Neurol ; 298(Pt B): 137-147, 2017 12.

Artigo em Inglês | MEDLINE | ID: mdl-28988910

10.

A comprehensive global genotype-phenotype database for rare diseases.

Trujillano, Daniel; Oprea, Gabriela-Elena; Schmitz, Yvonne; Bertoli-Avella, Aida M; Abou Jamra, Rami; Rolfs, Arndt.

Mol Genet Genomic Med ; 5(1): 66-75, 2017 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-28116331

11.

Immunochemical localization of vesicular monoamine transporter 2 (VMAT2) in mouse brain.

Cliburn, Rachel A; Dunn, Amy R; Stout, Kristen A; Hoffman, Carlie A; Lohr, Kelly M; Bernstein, Alison I; Winokur, Emily J; Burkett, James; Schmitz, Yvonne; Caudle, William M; Miller, Gary W.

J Chem Neuroanat ; 83-84: 82-90, 2017 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-27836486

12.

Fluorescent false neurotransmitter reveals functionally silent dopamine vesicle clusters in the striatum.

Pereira, Daniela B; Schmitz, Yvonne; Mészáros, József; Merchant, Paolomi; Hu, Gang; Li, Shu; Henke, Adam; Lizardi-Ortiz, José E; Karpowicz, Richard J; Morgenstern, Travis J; Sonders, Mark S; Kanter, Ellen; Rodriguez, Pamela C; Mosharov, Eugene V; Sames, Dalibor; Sulzer, David.

Nat Neurosci ; 19(4): 578-86, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26900925

13.

Altered dopamine release and uptake kinetics in mice lacking D2 receptors.

Schmitz, Yvonne; Schmauss, Claudia; Sulzer, David.

J Neurosci ; 22(18): 8002-9, 2002 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-12223553

14.

Analysing the impact of nucleo-cytoplasmic shuttling of ß-catenin and its antagonists APC, Axin and GSK3 on Wnt/ß-catenin signalling.

Schmitz, Yvonne; Rateitschak, Katja; Wolkenhauer, Olaf.

Cell Signal ; 25(11): 2210-21, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23872074

15.

Multi-compartmental modeling of SORLA's influence on amyloidogenic processing in Alzheimer's disease.

Lao, Angelyn; Schmidt, Vanessa; Schmitz, Yvonne; Willnow, Thomas E; Wolkenhauer, Olaf.

BMC Syst Biol ; 6: 74, 2012 Jun 22.

Artigo em Inglês | MEDLINE | ID: mdl-22727043

16.

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons.

Mosharov, Eugene V; Larsen, Kristin E; Kanter, Ellen; Phillips, Kester A; Wilson, Krystal; Schmitz, Yvonne; Krantz, David E; Kobayashi, Kazuto; Edwards, Robert H; Sulzer, David.

Neuron ; 62(2): 218-29, 2009 Apr 30.

Artigo em Inglês | MEDLINE | ID: mdl-19409267

17.

Presynaptic regulation of dopaminergic neurotransmission.

Schmitz, Yvonne; Benoit-Marand, Marianne; Gonon, François; Sulzer, David.

J Neurochem ; 87(2): 273-89, 2003 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-14511105

18.

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

Dauer, William; Kholodilov, Nikolai; Vila, Miquel; Trillat, Anne-Cecile; Goodchild, Rose; Larsen, Kristin E; Staal, Roland; Tieu, Kim; Schmitz, Yvonne; Yuan, Chao Annie; Rocha, Marcelo; Jackson-Lewis, Vernice; Hersch, Steven; Sulzer, David; Przedborski, Serge; Burke, Robert; Hen, Rene.

Proc Natl Acad Sci U S A ; 99(22): 14524-9, 2002 Oct 29.

Artigo em Inglês | MEDLINE | ID: mdl-12376616

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