RESUMO
There are two main types of chromosomal translocations known as reciprocal translocations and Robertsonian translocations. These chromosomal rearrangements are described as balanced when there is no significant loss of chromosomal material. Most carriers of balanced translocations are phenotypically normal and may not even know they are carriers of a balanced translocation. A parental balanced translocation may become apparent after having a child with congenital anomalies, during genetic testing, or while trying to conceive due to the increased risk of producing embryos with chromosomal imbalances. In vitro fertilization (IVF) in combination with preimplantation genetic testing (PGT) can potentially decrease the rate of miscarriages and increase the chance of a successful pregnancy. This is a case report of a 29-year-old female with a balanced translocation undergoing IVF with PGTstructural rearrangement (SR) and PGT-aneuploidy (A).
Assuntos
Diagnóstico Pré-Implantação , Translocação Genética , Gravidez , Feminino , Criança , Humanos , Adulto , Taxa de Gravidez , Testes Genéticos , Fertilização in vitroRESUMO
INTRODUCTION: The coronavirus pandemic has posed many challenges for healthcare facilities. One patient population particularly affected was pregnant women who delivered during the 2020 year. Many antenatal and postpartum services normally available were altered during the pandemic, including the number of available lactation consultants. This change in the availability of lactation consultants led to a decrease in face-to-face breastfeeding education and support for postpartum women. This study aimed to identify if the coronavirus pandemic had a negative effect on breastfeeding prevalence in a single tertiary healthcare center. METHOD: This study was a retrospective chart review with data collected from March 1, 2019-March 1, 2021. The study population was defined as pregnant women age 18 and older who delivered at a single hospital. The prevalence of women who stated they intended to exclusively breastfeed during the pandemic (March 1, 2020-March 1, 2021) was compared to the pre-pandemic year (March 1, 2019-Feb. 29, 2020) as a control. This breastfeeding prevalence was also compared to monthly county-specific coronavirus cases from the South Dakota Department of Health. RESULTS: The prevalence of women who stated they intended to exclusively breastfeed at the time of delivery during the study population was statistically less when compared to the previous pre-pandemic year. CONCLUSIONS: The coronavirus pandemic has posed many challenges for healthcare facilities. One patient populationThe exclusive breastfeeding prevalence was negatively affected during the coronavirus pandemic in this single tertiary health center. Knowledge of this demonstrates patient fears regarding breastfeeding during a pandemic and the importance of lactation education and consultation.