Detalhe da pesquisa
1.
Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.
Cell
; 184(13): 3426-3437.e8, 2021 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33991487
2.
RNA conformational propensities determine cellular activity.
Nature
; 617(7962): 835-841, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37198487
3.
Author Correction: RNA conformational propensities determine cellular activity.
Nature
; 618(7967): E35, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37296211
4.
Structural mechanism for HIV-1 TAR loop recognition by Tat and the super elongation complex.
Proc Natl Acad Sci U S A
; 115(51): 12973-12978, 2018 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514815
5.
Multiplex Substrate Profiling by Mass Spectrometry for Kinases as a Method for Revealing Quantitative Substrate Motifs.
Anal Chem
; 89(8): 4550-4558, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28322550
6.
Gene target specificity of the Super Elongation Complex (SEC) family: how HIV-1 Tat employs selected SEC members to activate viral transcription.
Nucleic Acids Res
; 43(12): 5868-79, 2015 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26007649
7.
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation.
Proc Natl Acad Sci U S A
; 111(1): E15-24, 2014 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24367103
8.
HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.
Proc Natl Acad Sci U S A
; 110(2): E123-31, 2013 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23251033
9.
Mercapto-pyrimidines are reversible covalent inhibitors of the papain-like protease (PLpro) and inhibit SARS-CoV-2 (SCoV-2) replication.
RSC Adv
; 13(26): 17667-17677, 2023 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37312993
10.
A covalent inhibitor targeting the papain-like protease from SARS-CoV-2 inhibits viral replication.
RSC Adv
; 13(16): 10636-10641, 2023 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37025664
11.
Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.
Nat Commun
; 13(1): 5282, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36075902
12.
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
bioRxiv
; 2021 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34013269
13.
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
Res Sq
; 2021 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34031651
14.
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.
Sci Adv
; 7(16)2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33853786
15.
Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation.
medRxiv
; 2021 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33758899
16.
Fragment Binding to the Nsp3 Macrodomain of SARS-CoV-2 Identified Through Crystallographic Screening and Computational Docking.
bioRxiv
; 2020 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33269349
17.
Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription.
Nat Commun
; 8: 14076, 2017 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28134250
18.
Toward understanding the structural basis of cyclin-dependent kinase 6 specific inhibition.
J Med Chem
; 49(13): 3826-31, 2006 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-16789739
19.
Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.
Elife
; 52016 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27731797
20.
Structural studies of the Nudix hydrolase DR1025 from Deinococcus radiodurans and its ligand complexes.
J Mol Biol
; 339(1): 103-16, 2004 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-15123424