Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails.

Stützer, Alexandra; Liokatis, Stamatios; Kiesel, Anja; Schwarzer, Dirk; Sprangers, Remco; Söding, Johannes; Selenko, Philipp; Fischle, Wolfgang.

Mol Cell ; 61(2): 247-59, 2016 Jan 21.

Artigo em Inglês | MEDLINE | ID: mdl-26778125

2.

Structural disorder of monomeric α-synuclein persists in mammalian cells.

Theillet, Francois-Xavier; Binolfi, Andres; Bekei, Beata; Martorana, Andrea; Rose, Honor May; Stuiver, Marchel; Verzini, Silvia; Lorenz, Dorothea; van Rossum, Marleen; Goldfarb, Daniella; Selenko, Philipp.

Nature ; 530(7588): 45-50, 2016 Feb 04.

Artigo em Inglês | MEDLINE | ID: mdl-26808899

3.

An NMR-Based Biosensor to Measure Stereospecific Methionine Sulfoxide Reductase Activities in Vitro and in Vivo*.

Sánchez-López, Carolina; Labadie, Natalia; Lombardo, Verónica A; Biglione, Franco A; Manta, Bruno; Jacob, Reeba Susan; Gladyshev, Vadim N; Abdelilah-Seyfried, Salim; Selenko, Philipp; Binolfi, Andres.

Chemistry ; 26(65): 14838-14843, 2020 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-32501570

4.

Quo Vadis Biomolecular NMR Spectroscopy?

Selenko, Philipp.

Int J Mol Sci ; 20(6)2019 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-30875725

5.

Time-Resolved NMR Analysis of Proteolytic α-Synuclein Processing in vitro and in cellulo.

Limatola, Antonio; Eichmann, Cédric; Jacob, Reeba Susan; Ben-Nissan, Gili; Sharon, Michal; Binolfi, Andres; Selenko, Philipp.

Proteomics ; 18(21-22): e1800056, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30260559

6.

Thermodynamics of protein destabilization in live cells.

Danielsson, Jens; Mu, Xin; Lang, Lisa; Wang, Huabing; Binolfi, Andres; Theillet, François-Xavier; Bekei, Beata; Logan, Derek T; Selenko, Philipp; Wennerström, Håkan; Oliveberg, Mikael.

Proc Natl Acad Sci U S A ; 112(40): 12402-7, 2015 Oct 06.

Artigo em Inglês | MEDLINE | ID: mdl-26392565

7.

Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.

Borcherds, Wade; Theillet, François-Xavier; Katzer, Andrea; Finzel, Ana; Mishall, Katie M; Powell, Anne T; Wu, Hongwei; Manieri, Wanda; Dieterich, Christoph; Selenko, Philipp; Loewer, Alexander; Daughdrill, Gary W.

Nat Chem Biol ; 10(12): 1000-2, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25362358

8.

A Multiplexed NMR-Reporter Approach to Measure Cellular Kinase and Phosphatase Activities in Real-Time.

Thongwichian, Rossukon; Kosten, Jonas; Benary, Uwe; Rose, Honor May; Stuiver, Marchel; Theillet, Francois-Xavier; Dose, Alexander; Koch, Birgit; Yokoyama, Hideki; Schwarzer, Dirk; Wolf, Jana; Selenko, Philipp.

J Am Chem Soc ; 137(20): 6468-71, 2015 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-25963544

9.

Copper binding to the N-terminally acetylated, naturally occurring form of alpha-synuclein induces local helical folding.

Miotto, Marco C; Valiente-Gabioud, Ariel A; Rossetti, Giulia; Zweckstetter, Markus; Carloni, Paolo; Selenko, Philipp; Griesinger, Christian; Binolfi, Andres; Fernández, Claudio O.

J Am Chem Soc ; 137(20): 6444-7, 2015 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-25939020

10.

Quantitative NMR analysis of Erk activity and inhibition by U0126 in a panel of patient-derived colorectal cancer cell lines.

Rose, Honor May; Stuiver, Marchel; Thongwichian, Rossukon; Theillet, Francois-Xavier; Feller, Stephan M; Selenko, Philipp.

Biochim Biophys Acta ; 1834(7): 1396-401, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23360766

11.

Site-specific mapping and time-resolved monitoring of lysine methylation by high-resolution NMR spectroscopy.

Theillet, François-Xavier; Liokatis, Stamatios; Jost, Jan Oliver; Bekei, Beata; Rose, Honor May; Binolfi, Andres; Schwarzer, Dirk; Selenko, Philipp.

J Am Chem Soc ; 134(18): 7616-9, 2012 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-22519908

12.

Cell signaling, post-translational protein modifications and NMR spectroscopy.

Theillet, Francois-Xavier; Smet-Nocca, Caroline; Liokatis, Stamatios; Thongwichian, Rossukon; Kosten, Jonas; Yoon, Mi-Kyung; Kriwacki, Richard W; Landrieu, Isabelle; Lippens, Guy; Selenko, Philipp.

J Biomol NMR ; 54(3): 217-36, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-23011410

13.

Bacterial in-cell NMR of human α-synuclein: a disordered monomer by nature?

Binolfi, Andres; Theillet, Francois-Xavier; Selenko, Philipp.

Biochem Soc Trans ; 40(5): 950-4, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22988846

14.

Paramagnetic relaxation enhancement to improve sensitivity of fast NMR methods: application to intrinsically disordered proteins.

Theillet, François-Xavier; Binolfi, Andres; Liokatis, Stamatis; Verzini, Silvia; Selenko, Philipp.

J Biomol NMR ; 51(4): 487-95, 2011 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22008951

15.

Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs).

Theillet, Francois-Xavier; Binolfi, Andres; Frembgen-Kesner, Tamara; Hingorani, Karan; Sarkar, Mohona; Kyne, Ciara; Li, Conggang; Crowley, Peter B; Gierasch, Lila; Pielak, Gary J; Elcock, Adrian H; Gershenson, Anne; Selenko, Philipp.

Chem Rev ; 114(13): 6661-714, 2014 Jul 09.

Artigo em Inglês | MEDLINE | ID: mdl-24901537

16.

α-Synuclein plasma membrane localization correlates with cellular phosphatidylinositol polyphosphate levels.

Jacob, Reeba Susan; Eichmann, Cédric; Dema, Alessandro; Mercadante, Davide; Selenko, Philipp.

Elife ; 102021 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-33587036

17.

Simultaneous detection of protein phosphorylation and acetylation by high-resolution NMR spectroscopy.

Liokatis, Stamatios; Dose, Alexander; Schwarzer, Dirk; Selenko, Philipp.

J Am Chem Soc ; 132(42): 14704-5, 2010 Oct 27.

Artigo em Inglês | MEDLINE | ID: mdl-20886851

18.

Megadalton-sized Dityrosine Aggregates of α-Synuclein Retain High Degrees of Structural Disorder and Internal Dynamics.

Verzini, Silvia; Shah, Maliha; Theillet, Francois-Xavier; Belsom, Adam; Bieschke, Jan; Wanker, Erich E; Rappsilber, Juri; Binolfi, Andres; Selenko, Philipp.

J Mol Biol ; 432(24): 166689, 2020 12 04.

Artigo em Inglês | MEDLINE | ID: mdl-33211011

19.

Cells, drugs and NMR.

Siegal, Gregg; Selenko, Philipp.

J Magn Reson ; 306: 202-212, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31358370

20.

Electroporated recombinant proteins as tools for in vivo functional complementation, imaging and chemical biology.

Alex, Amal; Piano, Valentina; Polley, Soumitra; Stuiver, Marchel; Voss, Stephanie; Ciossani, Giuseppe; Overlack, Katharina; Voss, Beate; Wohlgemuth, Sabine; Petrovic, Arsen; Wu, Yaowen; Selenko, Philipp; Musacchio, Andrea; Maffini, Stefano.

Elife ; 82019 07 16.

Artigo em Inglês | MEDLINE | ID: mdl-31310234

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