Tumor rejection in rats after inescapable or escapable shock.

Rats experienced inescapable, escapable, or no electric shock 1 day after being implanted with a Walker 256 tumor preparation. Only 27 percent of the rats receiving inescapable shock rejected the tumor, whereas 63 percent of the rats receiving escapable shock and 54 percent of the rats receiving no shock rejected the tumor. These results imply that lack of control over stressors reduces tumor rejection and decreases survival.

Cerebral blood flow changes in limbic regions induced by unsolvable anagram tasks.

OBJECTIVE: The study addressed the question of whether unsolvable as opposed to solvable cognitive problems activate discrete neuronal systems in the human brain. METHOD: Twelve healthy humans tried to solve unsolvable anagrams. Solvable anagrams and a resting baseline after each anagram task served as control conditions in a within-subject design. Activation was measured with the equilibrium infusion method by using 15O-labeled water and positron emission tomography, with absolute quantitation of anatomically defined regional cerebral blood flow (CBF). RESULTS: Compared to rest, both anagram tasks increased activity in frontal and temporal regions. The soluble task condition increased hippocampal activation and decreased mammillary bodies activity, while unsolvable anagrams were associated with increased CBF to the mamillary bodies and amygdala and decreased hippocampal activity. CONCLUSIONS: A limbic network integrating negative emotion and cognition seems reflected in reciprocal diencephalic and limbic activation with solvable and unsolvable anagrams. Since unsolvable anagrams have been used to induce learned helplessness in humans, this finding may provide an initial step toward clarifying its neural substrate.

Frustation and learned helplessness.

This article reports the transfer of learned helplessness from one aversive motivator, shock to another, frustration. In experiment 1, animals were trained to approach food in a runway and concomitantly exposed to either escapable, inescapable, or no shock in a different situation. Extinction was conducted in the runway, and subsequently the animals were tested for hurdle-jump escape from the frustrating goal box. Inescapably shocked rats failed to learn to hurdle-jump, whereas escapably or nonshocked animals learned the frustration escape response. Experiment 2 replicated the basic finidngs of Experiment 1 and showed transfer of learned helplessness from shock to frustration when no running response had been first acquired in the runway.

Explanatory style and cell-mediated immunity in elderly men and women.

Correlated pessimistic explanatory style--the belief that negative events are caused by internal, stable, and global factors--with lowered immunocompetence in a sample of 26 older adults. Two measures of cell-mediated immunity--T-helper cell/T-suppressor cell ratio and T-lymphocyte response to mitogen challenge--were lower in individuals with a pessimistic style, controlling for the influence of current health, depression, medication, recent weight change, sleep, and alcohol use. A relative increase in the percentage of T-suppressor cells seemed to underlie this immunosuppression. Although the mechanism by which explanatory style might influence immune function remains unknown, we speculate that a pessimistic style might be an important psychological risk factor--at least among older people--in the early course of certain immune-mediated diseases.

Predictors and consequences of childhood depressive symptoms: a 5-year longitudinal study.

A 5-year longitudinal study investigated the interrelationships among children's experiences of depressive symptoms, negative life events, explanatory style, and helplessness behaviors in social and achievement situations. The results revealed that early in childhood, negative events, but not explanatory style, predicted depressive symptoms; later in childhood, a pessimistic explanatory style emerged as a significant predictor of depressive symptoms, alone and in conjunction with negative events. When children suffered periods of depression, their explanatory styles not only deteriorated but remained pessimistic even after their depression subsided, presumably putting them at risk for future episodes of depression. Some children seem repeatedly prone to depressive symptoms over periods of at least 2 years. Depressed children consistently showed helpless behaviors in social and achievement settings.

Explanatory style across the life span: evidence for stability over 52 years.

Analyzed explanatory style across the life span. 30 Ss whose average age was 72 responded to questions about their current life and provided diaries or letters written in their youth, an average of 52 years earlier. A blind content analysis of explanatory style derived from these 2 sources revealed that explanatory style for negative events was stable throughout adult life (r = .54, p less than .002). In contrast, there appeared to be no stability of explanatory style for positive events between the same 2 time periods. These results suggest that explanatory style for negative events may persist across the life span and may constitute an enduring risk factor for depression, low achievement, and physical illness.

Self-blame and depressive symptoms.

Are internal attributions for bad events always associated with depression? The depressive symptoms of 87 female undergraduates correlated with blame directed at their own characters. In contrast, blame directed at their own behaviors correlated with lack of depressive symptoms. Behaviorally attributed bad events were seen as more controllable and their causes less stable and less global than were characterologically attributed bad events and their causes. Characterological blame increased with more negative life events during the last year, implying that individuals who blame their character may arrive at this attributional style by a covariation analysis. Finally, characterological blame did not precede the onset of depressive symptoms 6 or 12 weeks later. Thus, characterological blame may be a strong concomitant of depression, but not a cause.

Pessimistic explanatory style is a risk factor for physical illness: a thirty-five-year longitudinal study.

Explanatory style, the habitual ways in which individuals explain bad events, was extracted from open-ended questionnaires filled out by 99 graduates of the Harvard University classes of 1942-1944 at age 25. Physical health from ages 30 to 60 as measured by physician examination was related to earlier explanatory style. Pessimistic explanatory style (the belief that bad events are caused by stable, global, and internal factors) predicted poor health at ages 45 through 60, even when physical and mental health at age 25 were controlled. Pessimism in early adulthood appears to be a risk factor for poor health in middle and late adulthood.

Attributional style and the generality of learned helplessness.

According to the logic of the attribution reformulation of learned helplessness, the interaction of two factors influences whether helplessness experienced in one situation will transfer to a new situation. The model predicts that people who exhibit a style of attributing negative outcomes to global factors will show helplessness deficits in new situations that are either similar or dissimilar to the original situation in which they were helpless. In contrast, people who exhibit a style of attributing negative outcomes to only specific factors will show helplessness deficits in situations that are similar, but not dissimilar, to the original situation in which they were helpless. To test these predictions, we conducted two studies in which undergraduates with either a global or specific attributional style for negative outcomes were given one of three pretreatments in the typical helplessness triadic design: controllable bursts of noise, uncontrollable bursts of noise, or no noise. In Experiment 1, students were tested for helplessness deficits in a test situation similar to the pretreatment setting, whereas in Experiment 2, they were tested in a test situation dissimilar to the pretreatment setting. The findings were consistent with predictions of the reformulated helplessness theory.

Patient behavior in hospitals: helplessness, reactance, or both?

Forty-eight inpatients hospitalized for 1, 3, or 9 weeks and 24 outpatients were tested on cognitive tasks: poor performance and depressive symptoms increased with length of hospitalization, even as illness resolved. Further, increased hospitalization made patients more susceptible to the debilitating effect of uncontrollable events. Taken together, these results imply that the passive, compliant, and inanimate behavior of the "good patient" may be the result of learned helplessness engendered by hospitalization.

Learned helplessness in children: a longitudinal study of depression, achievement, and explanatory style.

In this longitudinal study, the depressive symptoms, life events, and explanatory styles of 168 school children were measured five times during the course of 1 year. Measures of school achievement were obtained once during the year. Depressive symptoms and explanatory styles were found to be quite stable over the year. As predicted by the reformulated learned helplessness theory, explanatory style both correlated with concurrent levels of depression and school achievement and predicted later changes in depression during the year. Depression also predicted later explanatory styles. The implications of these results for intervention with children with depressive symptoms or school achievement problems are discussed.

Learned helplessness, depression, and the attribution of failure.

Depressed and nondepressed college students received experience with solvable, unsolvable, or no discrimination problems. When later tested on a series of patterned anagrams, depressed groups performed worse than nondepressed groups, and unsolvable groups performed worse than solvable and control groups. As predicted by the learned helplessness model of depression, nondepressed subjects given unsolvable problems showed anagram deficits parallel to those found in naturally occurring depression. When depressed subjects attributed their failure to the difficulty of the problems rather than to their own incompetence, performance improved strikingly. So, failure in itself is apparently not sufficient to produce helplessness deficits in man, but failure that leads to a decreased belief in personal competence is sufficient.

Attributional styles and life events in the classroom: vulnerability and invulnerability to depressive mood reactions.

A core prediction of the reformulated model of learned helplessness and depression (Abramson, Seligman, & Teasdale, 1978) is that when confronted with the same negative life event, people who display a generalized tendency to attribute negative outcomes to internal, stable, or global factors should be more likely to experience a depressive mood reaction than people who typically attribute negative outcomes to external, unstable, or specific factors. We tested this prediction with a prospective design in a naturalistic setting by determining whether the content of college students' attributional styles at one point in time predicted the severity of their depressive mood response to receiving a low grade on a midterm exam at a subsequent point in time. Consistent with the prediction, students with an internal or global attributional style for negative outcomes at Time 1 experienced a depressive mood response when confronted with a subsequent low midterm grade, whereas students with an external or specific attributional style for negative outcomes were invulnerable to this depressive mood response. In contrast to the results for the internality and globality dimensions, students' scores along the stability attribution dimension were not correlated with the severity of their depressive mood response to the low midterm grade. In the absence of a negative life event (i.e., receipt of a high midterm grade), students' generalized tendencies to make internal or global attributions for negative outcomes at Time 1 were not significantly correlated with their subsequent changes in depressive mood although there was a nonsignificant positive correlation between severity of depressive mood response and the tendency to make global attributions for negative outcomes at Time 1.

The effectiveness of psychotherapy. The Consumer Reports study.

Consumer Reports (1995, November) published an article which concluded that patients benefited very substantially from psychotherapy, that long-term treatment did considerably better than short-term treatment, and that psychotherapy alone did not differ in effectiveness from medication plus psychotherapy. Furthermore, no specific modality of psychotherapy did better than any other for any disorder; psychologists, psychiatrists, and social workers did not differ in their effectiveness as treaters; and all did better than marriage counselors and long-term family doctoring. Patients whose length of therapy or choice of therapist was limited by insurance or managed care did worse. The methodological virtues and drawbacks of this large-scale survey are examined and contrasted with the more traditional efficacy study, in which patients are randomized into a manualized, fixed duration treatment or into control groups. I conclude that the Consumer Reports survey complements the efficacy method, and that the best features of these two methods can be combined into a more ideal method that will best provide empirical validation of psychotherapy.

Science as an ally of practice.

Well-founded criticisms of the Consumer Reports (CR; 1995) study of psychotherapy include possible bias of the CR sample; limitations of self-report; and the limitations of cross-sectional, retrospective data. Poorly founded criticisms concern "consumer satisfaction" and the claim that the remarkably good effects of long-term therapy resulted from spontaneous remission, that psychotherapy effects were small, and that nondoctoral providers did as well as doctoral-level providers. Both the experimental method (efficacy) and the observational method with causal modeling (effectiveness) answer complementary questions, and they both do so by eliminating alternative possible causes. Efficacy studies, however, cannot test long-term psychotherapy because long-term manuals cannot be written and patients cannot be randomized into two-year-long placebo controls, so the "empirical validation" of long-term therapy will likely come from effectiveness studies. Such studies of long-term therapy, of qualifications of providers, and of clinical judgment versus case management are urgently needed as practice confronts managed care.

Positive psychology. An introduction.

A science of positive subjective experience, positive individual traits, and positive institutions promises to improve quality of life and prevent the pathologies that arise when life is barren and meaningless. The exclusive focus on pathology that has dominated so much of our discipline results in a model of the human being lacking the positive features that make life worth living. Hope, wisdom, creativity, future mindedness, courage, spirituality, responsibility, and perseverance are ignored or explained as transformations of more authentic negative impulses. The 15 articles in this millennial issue of the American Psychologist discuss such issues as what enables happiness, the effects of autonomy and self-regulation, how optimism and hope affect health, what constitutes wisdom, and how talent and creativity come to fruition. The authors outline a framework for a science of positive psychology, point to gaps in our knowledge, and predict that the next century will see a science and profession that will come to understand and build the factors that allow individuals, communities, and societies to flourish.

Is pessimism a risk factor for depressive mood among community-dwelling older adults?

This study examined two senses in which pessimism might be a risk factor for depressive mood among older adults. The first was that a pessimistic explanatory style would predict changes toward depressive mood when combined with stressful life events. The second was that predictive pessimism, or thinking that bad events will happen in the future, would predict changes in depressive symptoms. We found an interaction between explanatory style and life stressors, but it was the optimists who were at higher risk for depressive symptoms after negative life events. We also found support for predictive pessimism, however, as a predictor of depressive symptoms over time.

Footsteps on the road to a positive psychology.

We have argued that psychology as a field has been preoccupied with the negative side of life and has left us with a view of human qualities that is warped and one-sided. Psychology is literally 'half-baked'. We need to bake the other half now. It is time for us to become equally concerned with the qualities and experiences that make life most worthwhile. A balance is needed between work that strives to relieve damage and work that endeavors to build strength. This balance is beautifully exemplified by Jack Rachman's work over the past 40 years. As an astute and compassionate clinician and researcher, Jack developed and evaluated effective treatments for some of the most debilitating anxiety disorders. At the same time, he was impressed by the resiliency of his clients and the courage they exhibited daily. His observations and studies of courage have helped to launch a systematic science of human strengths. They are giant footsteps on the road to a positive psychology.

Assessing explanatory style: the content analysis of verbatim explanations and the Attributional Style Questionnaire.

We compare two methods of assessing explanatory style--the content analysis of verbatim explanations (CAVE) and the Attributional Style Questionnaire (ASQ). The CAVE technique is a method that allows the researcher to analyze any naturally occurring verbatim materials for explanatory style. This technique permits the measurement of various populations that are unwilling or unable to take the ASQ. We administered the ASQ and Beck Depression Inventory (BDI) to 169 undergraduates and content analyzed the written causes on the ASQ for explanatory style by the CAVE technique. The CAVE technique correlated 0.71 with the ASQ (P less than 0.0001, n = 159) and -0.36 with BDI (P less than 0.0001, n = 159). The ASQ correlated -0.51 with the BDI (P less than 0.0001, n = 160). Both the CAVE technique and the ASQ seem to be valid devices for assessing explanatory style.

Is optimism heritable? A study of twins.

Is optimism heritable? We gave the Attributional Style Questionnaire (ASQ), a measure of optimism, to 115 monozygotic twin pairs (MZ) and 27 dizygotic twin pairs (DZ). The intraclass correlations of the ASQ scores were 0.48 for MZ twins (P < 0.0001) and 0 for DZ twins. Though the sample size of DZ twins is small, these results suggest that there may be a substantial genetic effect on optimism. We speculate, however, that the mechanism for the transmission of this, and other complex personality traits, may be highly indirect.