Detalhe da pesquisa
1.
STAT2 hinders STING intracellular trafficking and reshapes its activation in response to DNA damage.
Proc Natl Acad Sci U S A
; 120(16): e2216953120, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37036972
2.
Interferon induction by STING requires its translocation to the late endosomes.
Traffic
; 24(12): 576-586, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37658794
3.
Ubiquitination of the Transcription Factor IRF-3 Activates RIPA, the Apoptotic Pathway that Protects Mice from Viral Pathogenesis.
Immunity
; 44(5): 1151-61, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27178468
4.
IFN-Induced Protein with Tetratricopeptide Repeats 2 Limits Autoimmune Inflammation by Regulating Myeloid Cell Activation and Metabolic Activity.
J Immunol
; 210(6): 721-731, 2023 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36695771
5.
IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation.
Proc Natl Acad Sci U S A
; 119(37): e2121385119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36067309
6.
EGFR-mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions.
EMBO J
; 39(22): e104106, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32926474
7.
Cell-type-specific need of Ddx3 and PACT for interferon induction by RNA viruses.
J Virol
; 97(12): e0130423, 2023 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37982645
8.
Ifit2 restricts murine coronavirus spread to the spinal cord white matter and its associated myelin pathology.
J Virol
; 97(8): e0074923, 2023 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37504572
9.
PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c.
J Biol Chem
; 298(7): 102050, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35598827
10.
EGF-Receptor-Dependent TLR7 Signaling in Macrophages Promotes Glomerular Injury in Crescentic Glomerulonephritis.
Lab Invest
; 103(9): 100190, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37268107
11.
Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis.
PLoS Pathog
; 17(9): e1009950, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591940
12.
IRF3-mediated pathogenicity in a murine model of human hepatitis A.
PLoS Pathog
; 17(9): e1009960, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34591933
13.
Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.
EMBO J
; 37(8)2018 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29496741
14.
Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection.
PLoS Pathog
; 16(11): e1009034, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33253295
15.
Meet the terminator: The phosphatase PP2A puts brakes on IRF-3 activation.
Mol Cell
; 54(2): 210-1, 2014 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24766884
16.
Relative Contributions of the cGAS-STING and TLR3 Signaling Pathways to Attenuation of Herpes Simplex Virus 1 Replication.
J Virol
; 94(6)2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896590
17.
Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection.
PLoS Pathog
; 15(4): e1007674, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30958867
18.
TRAF4 binds to the juxtamembrane region of EGFR directly and promotes kinase activation.
Proc Natl Acad Sci U S A
; 115(45): 11531-11536, 2018 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30352854
19.
A new mechanism of interferon's antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7.
PLoS Pathog
; 14(1): e1006877, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29381763
20.
Constitutively Bound EGFR-Mediated Tyrosine Phosphorylation of TLR9 Is Required for Its Ability To Signal.
J Immunol
; 200(8): 2809-2818, 2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29531172