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1.
Bull Environ Contam Toxicol ; 87(3): 238-44, 2011 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-21725626

RESUMO

This study explored the hypothesis that acculturation is a risk factor for childhood lead poisoning in the Detroit area of Michigan. Blood lead levels (BLLs) were determined in 429 Arab American and African American children, aged 6 months to 15 years, who were receiving well-child examination in three Women, Infant, and Children (WIC) clinics in the city. Mean BLL was 3.8 ± 2.3 µg/dL (range: 1-18 µg/dL) and 3.3% of the children tested had blood lead values above the 10 µg/dL level of concern. Neither the age of the dwelling units nor ethnicity of the child was significantly associated with the BLL. Multivariable analyses instead identified a number of acculturation-related factors that are associated with elevation in blood lead including paternal education, language spoken at home (English only, English and Arabic, or Arabic only), home ownership, smoking in the home, and exposure of child to home health remedies. The difference in blood lead between Arab American children from families where Arabic only versus Arabic and English is spoken at home was found to be statistically significant. This study provides information showing that immigrant children are at heightened risk of being poisoned by lead which can be useful in identifying groups at risk of atypical exposures.


Assuntos
Árabes , Negro ou Afro-Americano , Exposição Ambiental/análise , Intoxicação por Chumbo/epidemiologia , Chumbo/metabolismo , Grupos Minoritários , Criança , Pré-Escolar , Cidades/epidemiologia , Demografia , Feminino , Humanos , Lactente , Chumbo/sangue , Chumbo/toxicidade , Intoxicação por Chumbo/diagnóstico , Masculino , Michigan/epidemiologia , Análise Multivariada , Pobreza , Medição de Risco
2.
Community Dent Oral Epidemiol ; 40(3): 267-76, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22150341

RESUMO

OBJECTIVES: To determine the efficacy of 5% sodium fluoride (NaF) varnish application in reducing caries increments in the permanent dentition of rural Brazilian school children over the course of 12 months. METHODS: A double-blind, randomized, placebo-controlled trial was conducted with 379 children aged 7-14 years who attended three schools in Brazil between January 2006 and December 2007. During this period, each school was visited four times at 6-month interval for recruitment, dental examinations, and fluoride varnish applications. Recruited children were randomly assigned to either a treatment (5% NaF varnish, n = 198) or a control group (placebo, n = 181). Trained interviewers collected data on oral health habits and sociodemographic characteristics from the children. Information on the child's diet was collected through a 7-day food frequency diary. Caries examinations were conducted using the International Caries Detection and Assessment System (ICDAS). The efficacy of fluoride varnish application on caries prevention was reported as a preventive fraction (PF). Crude caries increments of decayed and filled surfaces (DFS) were compared between fluoride varnish and placebo groups. A generalized linear model (GLM) was constructed to test the differences in DFS increments between the groups after accounting for confounding factors. RESULTS: Of the total sample (N = 379), 210 (55.4%) children had completed 12 months of follow-up including one or two applications of fluoride varnish or placebo. At the baseline examination, the children in the treatment and control groups presented on average 6.2 and 5.6 DFS, respectively (P < 0.001). After 12 months of follow-up, the children in the varnish group showed significantly lower DFS increments than did children in the control group (10.8 versus 13.3; P < 0.007), with PF of 40% (95% CI: 34.3-45.7%; P < 0.0001). CONCLUSIONS: The results of this study suggest that applications of 5% NaF varnish can be recommended as a public health measure for reducing caries incidence in this high-caries-risk population.


Assuntos
Cariostáticos/uso terapêutico , Cárie Dentária/prevenção & controle , Fluoretos Tópicos/uso terapêutico , Adolescente , Brasil/epidemiologia , Cariostáticos/administração & dosagem , Criança , Índice CPO , Cárie Dentária/epidemiologia , Método Duplo-Cego , Feminino , Fluoretos Tópicos/administração & dosagem , Humanos , Masculino , Higiene Bucal , População Rural , Fluoreto de Sódio/administração & dosagem , Fluoreto de Sódio/uso terapêutico
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