Clear cell carcinoma of endometrium.

Three cases of clear cell carcinoma of the endometrium are here reported. Clear cell carcinoma is a rare and aggressive type of endometrial adenocarcinoma. Patients are older and are in the menopause much longer than are patients with typical endometrial carcinoma. This fact may reflect the presence of counterbalanced sex hormones in the process of carcinogenesis.

Endometrial adenocarcinoma with psammoma bodies.

Psammoma bodies were found in less than 9% of 235 cases of endometrial carcinoma, considering both biopsies and surgical specimens. They may originate in papillary adenocarcinoma and do not indicate a slightly infiltrating or a well-differentiated tumor. The clinical profile of patients closely resembles that of women with endometrial carcinoma, but survival appears worse.

Immature teratoma of the ovary stage IA(i) treated with conservative surgery alone.

A review of a series of 245 ovarian teratomas disclosed 6 cases (2.4%) of immature teratoma. The tumors were FIGO stage IA(i) and histologic grade 1 (3 cases). With the exception of 2 specimens, all tumors were larger than 9 cm in the greatest diameter. All patients underwent conservative surgery alone and are alive without evidence of disease form 2.2 to 10.6 years (average 7.9 years). Our data support the view that conservative surgery is the treatment of choice for patients with stage IA(i), grade 1, immature teratoma, as well as for those with stage IA(i), grade 2 tumors, 9 cm or less in the greatest diameter.

Struma ovarii and Brenner tumor.

One struma ovarii with agregates of epithelial nests indistinguishable from Brenner tumor was studied. The presence of a communication between the nests and the follicles and the association of Brenner, mucinous and respiratory epithelium in the lining of 1 cyst in the same tumor strongly support the germ theory of Brenner tumors associated with teratomatous elements.