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1.
Biomed Eng Online ; 15(Suppl 2): 150, 2016 Dec 28.
Artigo em Inglês | MEDLINE | ID: mdl-28155693

RESUMO

BACKGROUND: Modeling neo-aortic valve for arterial switch surgical planning to simulate the neo-aortic valve closure performance. METHODS: We created five geometrical models of neo-aortic valve, namely model A, model B, model C, model D and model E with different size of sinotubular junction or sinus. The nodes at the ends of aorta and left ventricle duct fixed all the degrees of freedom. Transvalvular pressure of normal diastolic blood pressure of 54 mmHg was applied on the neo-aortic valve cusps. The neo-aortic valve closure performance was investigated by the parameters, such as stress of neo-aortic root, variation of neo-aortic valve ring as well as aortic valve cusps contact force in the cardiac diastole. RESULTS: The maximum stress of the five neo-aortic valves were 96.29, 98.34, 96.28, 98.26, and 90.60 kPa, respectively. Compared among five neo-aortic valve, aortic valve cusps contact forces were changed by 43.33, -10.00% enlarging or narrowing the sinotubular junction by 20% respectively based on the reference model A. The cusps contact forces were changed by 6.67, -23.33% with sinus diameter varying 1.2 times and 0.8 times respectively. CONCLUSIONS: Comparing with stress of healthy adult subjects, the neo-aortic valve of infant creates lower stress. It is evident that enlarging or narrowing the sinotubular junction within a range of 20% can increase or decrease the maximum stress and aortic valve cusps contact force of neo-aortic valve.


Assuntos
Valva Aórtica/fisiopatologia , Transposição das Grandes Artérias , Artérias/fisiopatologia , Adulto , Aorta/fisiopatologia , Valva Aórtica/fisiologia , Insuficiência da Valva Aórtica/fisiopatologia , Artérias/fisiologia , Pressão Sanguínea , Simulação por Computador , Diástole , Análise de Elementos Finitos , Humanos , Lactente , Modelos Cardiovasculares , Pressão , Valores de Referência , Estresse Mecânico
2.
Materials (Basel) ; 12(12)2019 Jun 24.
Artigo em Inglês | MEDLINE | ID: mdl-31238549

RESUMO

The macro-mesoscopic joint fatigue model containing hardening particles and crystal characteristics is established to study the effect of the hardening particles and the grain orientation on fatigue properties of an aluminum alloy friction stir welding (FSW) joint. The macroscopic model is composed of the weld nugget zone, thermo-mechanically affected zone, heat-affected zone, and base material, according to the metallurgical morphology and hardness distribution of the joint. Cyclic stress and strain data are used to determine the material properties. The fatigue parameters used in the calculation of cyclic stresses and strains are obtained with the four-point correlation method. The mesoscopic models of different zones are inserted into the joint macroscopic model as submodules. The models containing the information of hardening particles and grain orientation are established with crystal plasticity theory for the grains and isotropic hardening rule for the hardening particles. The effects of hardening particles and grain orientation on the stress and strain responses are discussed. The simulation results show that high-angle misorientation of adjacent grains hinders the stress transfer. The particle cluster or cracked particles intensify the stress and strain concentrations.

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