Hydroxyapatite/Silk Fibroin Composite Scaffold with a Porous Structure and Mechanical Strength Similar to Cancellous Bone by Electric Field-Induced Gel Technology.

Repair and regeneration of bone tissue defects is a multidimensional process that has been highly challenging to date. The artificial bone scaffold materials, which play a core role, still face the conflict that a biofriendly porous structure will reduce the mechanical performance and accelerate degradation. Herein, a multistage porous structured hydroxyapatite (HA)/silk fibroin (SF) composite scaffold (e-HA/SF) was successfully constructed by cleverly utilizing electric field-induced gel technology. The results indicated that the prepared e-HA/SF scaffolds possess biomimetic hierarchical porous structures with a suitable porosity similar to that of cancellous bone. The HA nanocrystals were uniformly encapsulated in the three-dimensional space of the composite scaffold, thus endowing the e-HA/SF composite scaffolds with an enhanced mechanical performance. Notably, the maximum compression stress and Young's modulus of e-HA/SF-2 scaffolds can reach 24.66 ± 0.88 and 28.91 ± 3.19 MPa, respectively, which are equivalent to those of cancellous bone. Such mechanical performance enhancement was previously unattainable through conventional freeze-drying strategies. Moreover, the introduction of bioactive nano-HA can trigger the optimal cell response in both static and dynamic cell culture experiments in vitro. The e-HA/SF composite scaffold developed in this study can better balance the conflict between the porous structure and mechanical and degradation properties of porous scaffolds.

The Impact of Sustainable Transformational Leadership on Sustainable Innovation Ambidexterity: Empirical Evidence From Green Building Industries of China.

Recognizing that building work will continually encompass, to a certain degree, unfavorable ecological consequences, green building has been encouraged and advocated as a managerial concept to progress in the construction segment. This research created a conceptual model that analyzed whether sustainable transformational leadership (STL) supported sustainable innovation ambidexterity (SIA) in green building industries. This research model was based on organizational support theory, hope theory, social cognitive theory, and attribution theory. This paper aimed to observe the relationship between STL with SIA via the mediating effect of psychological capital (PC). Furthermore, it examined the impact of perceived organizational support (POS) on PC. Moreover, it further examined the relationship between STL and POS. Likewise, it investigated the mediating effect of PC on the relationship between POS and SIA. Finally, it examined POS as a mediator between the relationship of STL and PC. The data for this study were collected from 600 workers employed at green building businesses in China. A questionnaire was delivered to the workers of green building corporations. According to the findings, STL was discovered to have a positive impact on PC. Furthermore, POS had a significant impact on PC. Moreover, PC significantly influenced SIA. Finally, STL was found to be in a significant relationship with POS. The outcomes of this research are extremely beneficial particularly in the situation of developing economies. This research contributes to the existing knowledge that employees with STL exhibit high PC, POS, and SIA in green building industries.

How to Keep Sustainable Development Between Enterprises and Employees? Evaluating the Impact of Person-Organization Fit and Person-Job Fit on Innovative Behavior.

High-tech industries often regard workers as their main source of value creation. In order to stimulate their employees' willingness to innovate and their innovative behavior and reduce the turnover intention, companies are now seeking to establish employer-employee relationships in which their employee's willingness to stay is not simply driven by extrinsic motivations. Therefore, it is an important topic in human resources for companies to implement measures that encourage employees to willingly devote themselves to their jobs and consider organizational growth as a component of their career development. This study aimed to investigate the effect of person-organization fit and person-job fit on employees' innovative behavior and turnover intention via the mediators including job satisfaction and organizational commitment. Six hundred ninety-seven employees from China's eight major high-tech industries were examined in this study, and the empirical results were analyzed using partial least squares. Based on the results, it is suggested that the person-organization fit and person-job fit are both crucial factors affecting employees' job satisfaction and organizational commitment, which, in turn, increase employees' willingness to innovate in their jobs and reduce their turnover intentions. Furthermore, this study could serve as a reference for companies in selecting employees, promoting job satisfaction, and developing strategies for sustainable development.

Enhancement of mechanical and biological performance on hydroxyapatite/silk fibroin scaffolds facilitated by microwave-assisted mineralization strategy.

Three-dimensional (3D) porous hydroxyapatite/silk fibroin (HA/SF) composite scaffolds with good mechanical and biological performance, could provide a good cellular survival microenvironment for bone repair. However, coating HA efficiently and uniformly on SF scaffolds remains a challenge. In this study, the effects of microwave-assisted technology and biomineralization methods on the nanostructure, chemical composition and deposition efficiency of HA coating have been comparatively analyzed. Furthermore, the mechanical performance of the prepared 3D scaffolds was evaluated, and rat bone marrow mesenchymal stem cells were seeded on the 3D scaffolds to investigate their cytocompatibility and osteogenic differentiation capacities. The results indicate that microwave-assisted technology could improve the HA deposition efficiency to enhance the compressive strengths of 3D HA/SF scaffolds. Especially, when microwave-assisted technology is introduced in simulated body fluid mineralization process, the obtained 3D composite scaffold could trigger the best cellular response, including promoting cell adhesion, spreading, proliferation and osteogenic differentiation. This study may provide a promising strategy for constructing 3D porous scaffolds with excellent mechanical and biological performance for bone tissue engineering.

Psychological Capital of MIS Development Teams, System Effectiveness, and Social Innovation: A Systematic Literature Review.

Inter-organizational information systems are critical in the modern business world, as a large portion of economic activities are done through inter-organizational collaborations. One such important collaboration is social innovation/entrepreneurship, which involves multiple parties from diverse areas cooperating in major tasks. Against such a backdrop, exploring beneficial factors for organizational members to actively develop and/or make good use of a management information system (MIS) for collaborative performance has become a vital research question. This conceptual paper argues that positive psychology is critical to encourage members to volunteer to construct an MIS that facilitates social innovation effectiveness. Specifically, we discuss the four dimensions of psychological capital (i.e., hope, optimism, self-efficacy, and resilience) on effective inter-organizational MIS attributes (e.g., connectivity), and on the consequences of social innovation. At the core of this discussion, we believe that a positive psychological foundation is a driver for staff effort to contribute to a better MIS, which could benefit social innovation success. This research contributes by offering inspiration for future studies to link the micro- and macro-level aspects of social innovation and entrepreneurship phenomena.

Acceptance of Online Medical Websites: An Empirical Study in China.

As a new type of public health service product, online medical websites (OMWs) are becoming quite popular. OMWs can address patients' basic medical problems remotely and give health guidance online. Compared to traditional hospitals, OMWs are more convenient and inexpensive, they can usually provide a better service for patients with poor medical conditions (especially in rural areas), and they also contribute to the rational distribution of medical resources. Therefore, key factors that affect patients' acceptance of OMWs must be identified to contribute to public health. By integrating perceived risk (PR) and the technology acceptance model (TAM), we proposed a modified TAM and clarified how PR and other factors affect patients' behavioral intention (BI) towards OMWs. A sample of 245 research participants in China took part in this study and the structural equation model (SEM) was used to test our hypotheses. The results revealed that perceived usefulness (PU) is a positive predictor of BI but has no significant effect on attitude (ATT), while perceived ease of use (PEOU) can affect BI through PU and attitude (ATT). Moreover, trust (TRU) was identified as a mediator of PR and PU/PEOU. Also, the doctor⁻patient relationship (DPR) was shown to moderate PR and TRU. In order to increase patients' BI, OMW providers need further innovations to improve patients' TRU and reduce their PR.

Assessing the Mediation Mechanism of Job Satisfaction and Organizational Commitment on Innovative Behavior: The Perspective of Psychological Capital.

Due to increasingly intense competition among companies, employees' innovative behavior has not only become a crucial factor for company development but also a topic of broad and current interest among companies and researchers. It is a requisite for companies to identify the antecedents of employees' innovative behavior. The main objective of this study was to investigate the effect of psychological capital (PsyCap) on employees' innovative behavior through its relationship with job satisfaction and organizational commitment. The partial least squares method was adopted in this study to analyze 266 employees from China. The results showed that PsyCap had positive effects on job satisfaction and organizational commitment, and verified the relationship between employees' innovative behavior and their job satisfaction and organizational commitment. Moreover, the mediating effect of PsyCap in terms of job satisfaction and organizational commitment on employees' innovative behavior was verified by a mediation analysis. Employees' innovative behavior is not only essential for the research and development department; rather, it is also important for other departments. The empirical results of this study show that companies should consider taking measures to increase employees' PsyCap, so as to enhance their innovative behavior. Lastly, the study also provided the managerial implications of its findings and recommendations for future research.

Silk-Fibroin-Assisted Cathodic Electrolytic Deposition of Calcium Phosphate for Biomedical Applications.

The biological responses of artificial biomaterials are affected strongly by its interfacial topography, especially from nano- to microscale. The structure controllability is essential for the design and synthesis of novel biomedical materials. Herein, the effect of soluble silk fibroin (SF) on the cathodic electrolytic deposition (ELD) behavior of octacalcium phosphate (OCP) coating is studied. It is observed that the addition of soluble SF does not change the inorganic phase of the coating (OCP), but it has a remarkable effect on the microstructure of the deposited coating. As a result, the OCP/SF composite coating possessed a micro/nano multilevel structure is finely constructed on titanium implant by using ELD technology. Such OCP/SF composite coating significantly promotes preosteoblast cells adhesion, spreading and proliferation. In general, effects have been made to produce an in-depth understanding of protein incorporated ELD technology to extend its application in the biomedical field. It provides a promising strategy to design and synthesize biomaterials with specific biomimetic structures and functions.