Detalhe da pesquisa
1.
Mec1 Is Activated at the Onset of Normal S Phase by Low-dNTP Pools Impeding DNA Replication.
Mol Cell
; 78(3): 396-410.e4, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32169162
2.
Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Mol Cell
; 76(5): 784-796.e6, 2019 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31588022
3.
Physical interactions between specifically regulated subpopulations of the MCM and RNR complexes prevent genetic instability.
PLoS Genet
; 20(5): e1011148, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38776358
4.
Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling.
Genes Dev
; 32(11-12): 822-835, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29899143
5.
Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress.
Mol Cell
; 68(2): 446-455.e3, 2017 Oct 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29033319
6.
SAMHD1 acts at stalled replication forks to prevent interferon induction.
Nature
; 557(7703): 57-61, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29670289
7.
Isocratic HPLC analysis for the simultaneous determination of dNTPs, rNTPs and ADP in biological samples.
Nucleic Acids Res
; 50(3): e18, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34850106
8.
Elimination of rNMPs from mitochondrial DNA has no effect on its stability.
Proc Natl Acad Sci U S A
; 117(25): 14306-14313, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32513727
9.
Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage.
EMBO J
; 37(21)2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30158111
10.
Rtt105 functions as a chaperone for replication protein A to preserve genome stability.
EMBO J
; 37(17)2018 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30065069
11.
High density of unrepaired genomic ribonucleotides leads to Topoisomerase 1-mediated severe growth defects in absence of ribonucleotide reductase.
Nucleic Acids Res
; 48(8): 4274-4297, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32187369
12.
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio.
Nucleic Acids Res
; 48(1): 264-277, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647103
13.
Mck1 defines a key S-phase checkpoint effector in response to various degrees of replication threats.
PLoS Genet
; 15(8): e1008136, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381575
14.
The development of compliance behavioral imperatives in public for management of covid-19.
Psychol Health Med
; : 1-8, 2022 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36120800
15.
The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity.
Nucleic Acids Res
; 47(8): 3986-3995, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30698744
16.
A genetic screen pinpoints ribonucleotide reductase residues that sustain dNTP homeostasis and specifies a highly mutagenic type of dNTP imbalance.
Nucleic Acids Res
; 47(1): 237-252, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30462295
17.
De novo dNTP production is essential for normal postnatal murine heart development.
J Biol Chem
; 294(44): 15889-15897, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31300555
18.
Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres.
PLoS Genet
; 13(10): e1007082, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-29069086
19.
Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.
Proc Natl Acad Sci U S A
; 114(22): E4442-E4451, 2017 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28416670
20.
Trends in Chronic Liver Disease-Related Hospitalizations: A Population-Based Study.
Am J Gastroenterol
; 114(1): 98-106, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30333543