Detalhe da pesquisa
1.
Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation.
Cell
; 186(12): 2593-2609.e18, 2023 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37209683
2.
Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca2+ entry and accelerated differentiation.
Mol Psychiatry
; 2023 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402854
3.
SARS-CoV-2 promotes microglial synapse elimination in human brain organoids.
Mol Psychiatry
; 27(10): 3939-3950, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36198765
4.
N-3 polyunsaturated fatty acids promote astrocyte differentiation and neurotrophin production independent of cAMP in patient-derived neural stem cells.
Mol Psychiatry
; 26(9): 4605-4615, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504049
5.
Aberrant mitochondrial function in patient-derived neural cells from CDKL5 deficiency disorder and Rett syndrome.
Hum Mol Genet
; 28(21): 3625-3636, 2019 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31518399
6.
A microRNA cluster in the Fragile-X region expressed during spermatogenesis targets FMR1.
EMBO Rep
; 20(2)2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30573526
7.
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis.
Proc Natl Acad Sci U S A
; 114(22): E4462-E4471, 2017 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28500272
8.
Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.
J Neurosci
; 37(41): 9917-9924, 2017 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28912154
9.
Response to: X-linked miR-506 family miRNAs promote FMRP expression in mouse spermatogonia.
EMBO Rep
; 21(1): e49354, 2020 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31808609
10.
ß2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome.
Proc Natl Acad Sci U S A
; 111(27): 9947-52, 2014 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24958851
11.
CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors.
Proc Natl Acad Sci U S A
; 111(42): E4468-77, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25294932
12.
Human iPSC models of neuronal ceroid lipofuscinosis capture distinct effects of TPP1 and CLN3 mutations on the endocytic pathway.
Hum Mol Genet
; 23(8): 2005-22, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24271013
13.
PDGFRß expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation.
J Cell Sci
; 125(Pt 9): 2276-87, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22344267
14.
Loss of Function in the Neurodevelopmental Disease and Schizophrenia-Associated Gene CYFIP1 in Human Microglia-like Cells Supports a Functional Role in Synaptic Engulfment.
Biol Psychiatry
; 95(7): 676-686, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37573007
15.
Maternal SARS-CoV-2 impacts fetal placental macrophage programs and placenta-derived microglial models of neurodevelopment.
medRxiv
; 2023 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38234776
16.
Small-molecule screen reveals pathways that regulate C4 secretion in stem cell-derived astrocytes.
Stem Cell Reports
; 18(1): 237-253, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36563689
17.
Patient-Derived In Vitro Models of Microglial Function and Synaptic Engulfment in Schizophrenia.
Biol Psychiatry
; 92(6): 470-479, 2022 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35232567
18.
Human cerebral spheroids undergo 4-aminopyridine-induced, activity associated changes in cellular composition and microrna expression.
Sci Rep
; 12(1): 9143, 2022 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35650420
19.
Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia.
Nat Commun
; 13(1): 6427, 2022 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36329007
20.
ARHGDIA Confers Selective Advantage to Dissociated Human Pluripotent Stem Cells.
Stem Cells Dev
; 30(14): 705-713, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34036793