Detalhe da pesquisa
1.
Unique Binding Sites of Uricosuric Agent Dotinurad for Selective Inhibition of Renal Uric Acid Reabsorptive Transporter URAT1.
J Pharmacol Exp Ther
; 2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38670801
2.
Magnitude of Fruit Juice-Drug Interactions Due to Osmolality-Dependent Fluid Secretion: Differences among Apple, Orange, and Grapefruit Juices.
Biol Pharm Bull
; 47(1): 72-78, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38171780
3.
Quantitative analysis of the impact of membrane permeability on intestinal first-pass metabolism of CYP3A substrates.
Biopharm Drug Dispos
; 45(1): 3-14, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38085672
4.
The Glycosylated N-Terminal Domain of MUC1 Is Involved in Chemoresistance by Modulating Drug Permeation Across the Plasma Membrane.
Mol Pharmacol
; 103(3): 166-175, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36804202
5.
Potentiation of the Uricosuric Effect of Dotinurad by Trans-Inhibition of the Uric Acid Reabsorptive Transporter 1.
Drug Metab Dispos
; 51(11): 1527-1535, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643882
6.
Identification of 5-Carboxyfluorescein as a Probe Substrate of SLC46A3 and Its Application in a Fluorescence-Based In Vitro Assay Evaluating the Interaction with SLC46A3.
Mol Pharm
; 20(1): 491-499, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36458938
7.
Macrolide and Ketolide Antibiotics Inhibit the Cytotoxic Effect of Trastuzumab Emtansine in HER2-Positive Breast Cancer Cells: Implication of a Potential Drug-ADC Interaction in Cancer Chemotherapy.
Mol Pharm
; 20(12): 6130-6139, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37971309
8.
Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening.
Pharm Res
; 39(7): 1549-1559, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35314999
9.
Evaluation of Platinum Anticancer Drug-Induced Kidney Injury in Primary Culture of Rat Kidney Tissue Slices by Using Gas-Permeable Plates.
Biol Pharm Bull
; 45(3): 316-322, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35228397
10.
Model Analysis of the Apparent Saturation Kinetics of Purine Nucleobase Uptake in Cells co-Expressing Transporter and Metabolic Enzyme.
Pharm Res
; 38(9): 1585-1592, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34435306
11.
Utilization of Sodium Nitroprusside as an Intestinal Permeation Enhancer for Lipophilic Drug Absorption Improvement in the Rat Proximal Intestine.
Molecules
; 26(21)2021 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34770805
12.
Effect of Osmolality on the Pharmacokinetic Interaction between Apple Juice and Atenolol in Rats.
Drug Metab Dispos
; 47(4): 386-391, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30622163
13.
Mucins are Involved in the Intestinal Permeation of Lipophilic Drugs in the Proximal Region of Rat Small Intestine.
Pharm Res
; 36(11): 162, 2019 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31529336
14.
Organic anion transporter 1 (OAT1/SLC22A6) enhances bioluminescence based on d-luciferin-luciferase reaction in living cells by facilitating the intracellular accumulation of d-luciferin.
Biochem Biophys Res Commun
; 495(3): 2152-2157, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29273507
15.
Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions.
J Pharmacol Exp Ther
; 361(2): 246-258, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28275201
16.
Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins.
Drug Metab Dispos
; 43(12): 1872-81, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26374172
17.
The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles.
Drug Metab Dispos
; 43(8): 1226-35, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26021325
18.
Substrate- and dose-dependent drug interactions with grapefruit juice caused by multiple binding sites on OATP2B1.
Pharm Res
; 31(8): 2035-43, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24549825
19.
The Use of Carboxyfluorescein Reveals the Transport Function of MCT6/SLC16A5 Associated with CD147 as a Chloride-Sensitive Organic Anion Transporter in Mammalian Cells.
J Pharm Sci
; 113(4): 1113-1120, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38160712
20.
MDR1 is related to intestinal epithelial injury induced by acetylsalicylic acid.
Cell Physiol Biochem
; 32(4): 942-50, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24107783