Detalhe da pesquisa
1.
Single-domain antibodies reveal unique borrelicidal epitopes on the Lyme disease vaccine antigen, outer surface protein A (OspA).
Infect Immun
; 92(4): e0008424, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38470113
2.
Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies.
PLoS Pathog
; 18(1): e1010169, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34990480
3.
Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917.
PLoS Pathog
; 18(9): e1010713, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36107831
4.
Neutralization of Typhoid Toxin by Alpaca-Derived, Single-Domain Antibodies Targeting the PltB and CdtB Subunits.
Infect Immun
; 90(2): e0051521, 2022 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34898253
5.
Single-domain antibodies pinpoint potential targets within Shigella invasion plasmid antigen D of the needle tip complex for inhibition of type III secretion.
J Biol Chem
; 292(40): 16677-16687, 2017 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28842484
6.
Use of VHH antibodies for the development of antigen detection test for visceral leishmaniasis.
Parasite Immunol
; 40(11): e12584, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30120856
7.
A Diverse Set of Single-domain Antibodies (VHHs) against the Anthrax Toxin Lethal and Edema Factors Provides a Basis for Construction of a Bispecific Agent That Protects against Anthrax Infection.
J Biol Chem
; 291(41): 21596-21606, 2016 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27539858
8.
Mechanisms of Ricin Toxin Neutralization Revealed through Engineered Homodimeric and Heterodimeric Camelid Antibodies.
J Biol Chem
; 290(46): 27880-9, 2015 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26396190
9.
A heterodimer of a VHH (variable domains of camelid heavy chain-only) antibody that inhibits anthrax toxin cell binding linked to a VHH antibody that blocks oligomer formation is highly protective in an anthrax spore challenge model.
J Biol Chem
; 290(10): 6584-95, 2015 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25564615
10.
Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.
Proteins
; 84(8): 1162-72, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27159829
11.
Using Antigen-antibody Binding Kinetic Parameters to Understand Single-Molecule Array Immunoassay Performance.
Anal Chem
; 88(23): 11335-11339, 2016 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27779850
12.
Identification of Targeting Peptides for Mucosal Delivery in Sheep and Mice.
Mol Pharm
; 13(1): 202-10, 2016 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26568284
13.
Adenovirus vector expressing Stx1/Stx2-neutralizing agent protects piglets infected with Escherichia coli O157:H7 against fatal systemic intoxication.
Infect Immun
; 83(1): 286-91, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25368111
14.
Algal chloroplast produced camelid VH H antitoxins are capable of neutralizing botulinum neurotoxin.
Plant Biotechnol J
; 13(1): 117-24, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25229405
15.
A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice.
J Infect Dis
; 210(6): 964-72, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24683195
16.
Stepwise engineering of heterodimeric single domain camelid VHH antibodies that passively protect mice from ricin toxin.
J Biol Chem
; 288(51): 36538-47, 2013 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24202178
17.
Generation of a phage-display library of single-domain camelid VH H antibodies directed against Chlamydomonas reinhardtii antigens, and characterization of VH Hs binding cell-surface antigens.
Plant J
; 76(4): 709-17, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23980604
18.
Adenoviral targeting using genetically incorporated camelid single variable domains.
Lab Invest
; 94(8): 893-905, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24933423
19.
Persistence of Botulinum neurotoxin inactivation of nerve function.
Curr Top Microbiol Immunol
; 364: 179-96, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23239354
20.
A single VHH-based toxin-neutralizing agent and an effector antibody protect mice against challenge with Shiga toxins 1 and 2.
Infect Immun
; 81(12): 4592-603, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24082082