Detalhe da pesquisa
1.
Retinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and ß-cell mass.
FASEB J
; 29(2): 671-83, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25389133
2.
Regulatory Mechanisms of Vitamin D3 on Production of Nitric Oxide and Pro-inflammatory Cytokines in Microglial BV-2 Cells.
Neurochem Res
; 41(11): 2848-2858, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401255
3.
Retinoid agonist Am80-enhanced neutrophil bactericidal activity arising from granulopoiesis in vitro and in a neutropenic mouse model.
Blood
; 121(6): 996-1007, 2013 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23243275
4.
Docking simulations suggest that all-trans retinoic acid could bind to retinoid X receptors.
J Comput Aided Mol Des
; 29(10): 975-88, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26384496
5.
Mitogen-activated protein kinases regulate expression of neuronal nitric oxide synthase and neurite outgrowth via non-classical retinoic acid receptor signaling in human neuroblastoma SH-SY5Y cells.
J Pharmacol Sci
; 129(2): 119-26, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26422672
6.
Retinoic acid receptor stimulation ameliorates experimental autoimmune optic neuritis.
Clin Exp Ophthalmol
; 43(6): 558-67, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24612001
7.
Suppression of CXCL2 upregulation underlies the therapeutic effect of the retinoid Am80 on intracerebral hemorrhage in mice.
J Neurosci Res
; 92(8): 1024-34, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24659080
8.
Am80, a retinoic acid receptor agonist, ameliorates murine vasculitis through the suppression of neutrophil migration and activation.
Arthritis Rheum
; 65(2): 503-12, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23203767
9.
Transdermal administration of aqueous pregabalin solution as a potential treatment option for patients with neuropathic pain to avoid central nervous system-mediated side effects.
Biol Pharm Bull
; 37(11): 1816-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25212662
10.
Diarylamines incorporating hexahydrophenalene or octahydrobenzoheptalene as retinoid X receptor (RXR)-specific agonists.
Chem Pharm Bull (Tokyo)
; 62(3): 254-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24583779
11.
Retinoids ameliorate insulin resistance in a leptin-dependent manner in mice.
Hepatology
; 56(4): 1319-30, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22531980
12.
Deprotonation equilibrium of 5-tropolonediazonium salt strongly favors 1,2,5-tropoquinone-5-diazide structure in certain solvents.
J Org Chem
; 78(11): 5470-5, 2013 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23706059
13.
Structure-activity relationship study on benzoic acid part of diphenylamine-based retinoids.
Bioorg Med Chem Lett
; 23(1): 81-4, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23217961
14.
Design, synthesis and evaluation of retinoids with novel bulky hydrophobic partial structures.
Bioorg Med Chem
; 21(14): 4342-50, 2013 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23685180
15.
Synthesis of Am80 (tamibarotene) prodrug candidates, congeners and metabolites.
Chem Pharm Bull (Tokyo)
; 61(8): 846-52, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23902867
16.
(R)- and (S)-4-Amino-3-(trimethylsilyl)methylbutanoic acids ameliorate neuropathic pain without central nervous system-related side effects.
Bioorg Med Chem Lett
; 22(24): 7602-4, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23103098
17.
Tamibarotene: a candidate retinoid drug for Alzheimer's disease.
Biol Pharm Bull
; 35(8): 1206-12, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22863914
18.
Midbrain dopaminergic neurons utilize nitric oxide/cyclic GMP signaling to recruit ERK that links retinoic acid receptor stimulation to up-regulation of BDNF.
J Neurochem
; 116(3): 323-33, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20649843
19.
Diphenylamine-based retinoid antagonists: regulation of RAR and RXR function depending on the N-substituent.
Bioorg Med Chem
; 19(8): 2501-7, 2011 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21459577
20.
Synthetic retinoid AM80 inhibits Th17 cells and ameliorates experimental autoimmune encephalomyelitis.
Am J Pathol
; 174(6): 2234-45, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19389933