Detalhe da pesquisa
1.
Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.
Nat Immunol
; 24(11): 1854-1866, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37857825
2.
Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids.
Acta Neuropathol
; 142(5): 807-825, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34453582
3.
Activation of FAK/Rac1/Cdc42-GTPase signaling ameliorates impaired microglial migration response to Aß42 in triggering receptor expressed on myeloid cells 2 loss-of-function murine models.
FASEB J
; 34(8): 10984-10997, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32613609
4.
Dentate Gyrus Contributes to Retrieval as well as Encoding: Evidence from Context Fear Conditioning, Recall, and Extinction.
J Neurosci
; 37(26): 6359-6371, 2017 06 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28546308
5.
Correction to: Apolipoprotein E regulates lipid metabolism and αsynuclein pathology in human iPSCderived cerebral organoids.
Acta Neuropathol
; 143(1): 119-121, 2022 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34724591
6.
CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly.
Sci Adv
; 10(14): eadk3674, 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38569027
7.
Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease.
Mol Neurodegener
; 18(1): 46, 2023 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37434208
8.
Upregulation of sFRP1 Is More Profound in Female than Male 5xFAD Mice and Positively Associated with Amyloid Pathology.
J Alzheimers Dis
; 95(2): 399-405, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37545238
9.
LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4.
JCI Insight
; 8(7)2023 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37036005
10.
Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology.
Mol Neurodegener
; 18(1): 8, 2023 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36721205
11.
Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination.
Mol Neurodegener
; 17(1): 75, 2022 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36419137
12.
Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.
Nat Neurosci
; 25(8): 1020-1033, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35915180
13.
Preparation of single cell suspensions enriched in mouse brain vascular cells for single-cell RNA sequencing.
STAR Protoc
; 2(3): 100715, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34401781
14.
Vascular ApoE4 Impairs Behavior by Modulating Gliovascular Function.
Neuron
; 109(3): 438-447.e6, 2021 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33321072
15.
APOE3-Jacksonville (V236E) variant reduces self-aggregation and risk of dementia.
Sci Transl Med
; 13(613): eabc9375, 2021 Sep 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34586832
16.
APOE2: protective mechanism and therapeutic implications for Alzheimer's disease.
Mol Neurodegener
; 15(1): 63, 2020 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33148290
17.
A mouse model of stress-enhanced fear learning demonstrates extinction-sensitive and extinction-resistant effects of footshock stress.
Behav Brain Res
; 379: 112391, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31785363
18.
APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.
Nat Commun
; 11(1): 5540, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33139712
19.
Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways.
Neuron
; 106(5): 727-742.e6, 2020 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32199103
20.
APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid.
Sci Transl Med
; 12(529)2020 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32024798