Detalhe da pesquisa
1.
Statin regulated ERK5 stimulates tight junction formation and reduces permeability in human cardiac endothelial cells.
J Cell Physiol
; 233(1): 186-200, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28639275
2.
Systemic gut microbial modulation of bile acid metabolism in host tissue compartments.
Proc Natl Acad Sci U S A
; 108 Suppl 1: 4523-30, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20837534
3.
Data science in drug discovery safety: Challenges and opportunities.
Exp Biol Med (Maywood)
; 248(21): 1993-2000, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38062553
4.
Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents.
J Physiol
; 590(24): 6389-402, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23045346
5.
Analysis of ß-catenin gene mutations and gene expression in liver tumours of C57BL/10J mice produced by chronic administration of sodium phenobarbital.
Toxicology
; 430: 152343, 2020 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31836555
6.
Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis.
Am J Nephrol
; 28(5): 823-30, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18535368
7.
In Vitro Modeling of Bile Acid Processing by the Human Fecal Microbiota.
Front Microbiol
; 9: 1153, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29922256
8.
Towards better models and mechanistic biomarkers for drug-induced gastrointestinal injury.
Pharmacol Ther
; 172: 181-194, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28132905
9.
Cardiotoxic drugs Herceptin and doxorubicin inhibit cardiac microvascular endothelial cell barrier formation resulting in increased drug permeability.
Biol Open
; 5(10): 1362-1370, 2016 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27543060
10.
Cardiac Non-myocyte Cells Show Enhanced Pharmacological Function Suggestive of Contractile Maturity in Stem Cell Derived Cardiomyocyte Microtissues.
Toxicol Sci
; 152(1): 99-112, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27125969
11.
Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1.
J Cardiovasc Pharmacol Ther
; 19(2): 209-19, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24414167
12.
Probiotic administration attenuates myocardial hypertrophy and heart failure after myocardial infarction in the rat.
Circ Heart Fail
; 7(3): 491-9, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24625365
13.
Phenotypic profiling of structural cardiotoxins in vitro reveals dependency on multiple mechanisms of toxicity.
Toxicol Sci
; 132(2): 317-26, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23315586
14.
Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells.
J Am Soc Nephrol
; 15(9): 2258-65, 2004 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15339975