Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma.

Neftel, Cyril; Laffy, Julie; Filbin, Mariella G; Hara, Toshiro; Shore, Marni E; Rahme, Gilbert J; Richman, Alyssa R; Silverbush, Dana; Shaw, McKenzie L; Hebert, Christine M; Dewitt, John; Gritsch, Simon; Perez, Elizabeth M; Gonzalez Castro, L Nicolas; Lan, Xiaoyang; Druck, Nicholas; Rodman, Christopher; Dionne, Danielle; Kaplan, Alexander; Bertalan, Mia S; Small, Julia; Pelton, Kristine; Becker, Sarah; Bonal, Dennis; Nguyen, Quang-De; Servis, Rachel L; Fung, Jeremy M; Mylvaganam, Ravindra; Mayr, Lisa; Gojo, Johannes; Haberler, Christine; Geyeregger, Rene; Czech, Thomas; Slavc, Irene; Nahed, Brian V; Curry, William T; Carter, Bob S; Wakimoto, Hiroaki; Brastianos, Priscilla K; Batchelor, Tracy T; Stemmer-Rachamimov, Anat; Martinez-Lage, Maria; Frosch, Matthew P; Stamenkovic, Ivan; Riggi, Nicolo; Rheinbay, Esther; Monje, Michelle; Rozenblatt-Rosen, Orit; Cahill, Daniel P; Patel, Anoop P.

Cell ; 178(4): 835-849.e21, 2019 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-31327527

2.

Electrical and synaptic integration of glioma into neural circuits.

Venkatesh, Humsa S; Morishita, Wade; Geraghty, Anna C; Silverbush, Dana; Gillespie, Shawn M; Arzt, Marlene; Tam, Lydia T; Espenel, Cedric; Ponnuswami, Anitha; Ni, Lijun; Woo, Pamelyn J; Taylor, Kathryn R; Agarwal, Amit; Regev, Aviv; Brang, David; Vogel, Hannes; Hervey-Jumper, Shawn; Bergles, Dwight E; Suvà, Mario L; Malenka, Robert C; Monje, Michelle.

Nature ; 573(7775): 539-545, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31534222

3.

Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma.

Drexler, Richard; Khatri, Robin; Schüller, Ulrich; Eckhardt, Alicia; Ryba, Alice; Sauvigny, Thomas; Dührsen, Lasse; Mohme, Malte; Ricklefs, Tammo; Bode, Helena; Hausmann, Fabian; Huber, Tobias B; Bonn, Stefan; Voß, Hannah; Neumann, Julia E; Silverbush, Dana; Hovestadt, Volker; Suvà, Mario L; Lamszus, Katrin; Gempt, Jens; Westphal, Manfred; Heiland, Dieter H; Hänzelmann, Sonja; Ricklefs, Franz L.

Acta Neuropathol ; 147(1): 21, 2024 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-38244080

4.

Inferring cancer progression from Single-Cell Sequencing while allowing mutation losses.

Ciccolella, Simone; Ricketts, Camir; Soto Gomez, Mauricio; Patterson, Murray; Silverbush, Dana; Bonizzoni, Paola; Hajirasouliha, Iman; Della Vedova, Gianluca.

Bioinformatics ; 37(3): 326-333, 2021 04 20.

Artigo em Inglês | MEDLINE | ID: mdl-32805010

5.

ANAT 2.0: reconstructing functional protein subnetworks.

Almozlino, Yomtov; Atias, Nir; Silverbush, Dana; Sharan, Roded.

BMC Bioinformatics ; 18(1): 495, 2017 Nov 16.

Artigo em Inglês | MEDLINE | ID: mdl-29145805

6.

Network orientation via shortest paths.

Silverbush, Dana; Sharan, Roded.

Bioinformatics ; 30(10): 1449-55, 2014 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-24470573

7.

A prognostic neural epigenetic signature in high-grade glioma.

Drexler, Richard; Khatri, Robin; Sauvigny, Thomas; Mohme, Malte; Maire, Cecile L; Ryba, Alice; Zghaibeh, Yahya; Dührsen, Lasse; Salviano-Silva, Amanda; Lamszus, Katrin; Westphal, Manfred; Gempt, Jens; Wefers, Annika K; Neumann, Julia E; Bode, Helena; Hausmann, Fabian; Huber, Tobias B; Bonn, Stefan; Jütten, Kerstin; Delev, Daniel; Weber, Katharina J; Harter, Patrick N; Onken, Julia; Vajkoczy, Peter; Capper, David; Wiestler, Benedikt; Weller, Michael; Snijder, Berend; Buck, Alicia; Weiss, Tobias; Göller, Pauline C; Sahm, Felix; Menstel, Joelle Aline; Zimmer, David Niklas; Keough, Michael B; Ni, Lijun; Monje, Michelle; Silverbush, Dana; Hovestadt, Volker; Suvà, Mario L; Krishna, Saritha; Hervey-Jumper, Shawn L; Schüller, Ulrich; Heiland, Dieter H; Hänzelmann, Sonja; Ricklefs, Franz L.

Nat Med ; 2024 May 17.

Artigo em Inglês | MEDLINE | ID: mdl-38760585

8.

Epigenetic neural glioblastoma enhances synaptic integration and predicts therapeutic vulnerability.

Drexler, Richard; Khatri, Robin; Sauvigny, Thomas; Mohme, Malte; Maire, Cecile L; Ryba, Alice; Zghaibeh, Yahya; Dührsen, Lasse; Salviano-Silva, Amanda; Lamszus, Katrin; Westphal, Manfred; Gempt, Jens; Wefers, Annika K; Neumann, Julia; Bode, Helena; Hausmann, Fabian; Huber, Tobias B; Bonn, Stefan; Jütten, Kerstin; Delev, Daniel; Weber, Katharina J; Harter, Patrick N; Onken, Julia; Vajkoczy, Peter; Capper, David; Wiestler, Benedikt; Weller, Michael; Snijder, Berend; Buck, Alicia; Weiss, Tobias; Keough, Michael B; Ni, Lijun; Monje, Michelle; Silverbush, Dana; Hovestadt, Volker; Suvà, Mario L; Krishna, Saritha; Hervey-Jumper, Shawn L; Schüller, Ulrich; Heiland, Dieter H; Hänzelmann, Sonja; Ricklefs, Franz L.

bioRxiv ; 2023 Aug 07.

Artigo em Inglês | MEDLINE | ID: mdl-37609137

9.

Evolution of fibroblasts in the lung metastatic microenvironment is driven by stage-specific transcriptional plasticity.

Shani, Ophir; Raz, Yael; Monteran, Lea; Scharff, Ye'ela; Levi-Galibov, Oshrat; Megides, Or; Shacham, Hila; Cohen, Noam; Silverbush, Dana; Avivi, Camilla; Sharan, Roded; Madi, Asaf; Scherz-Shouval, Ruth; Barshack, Iris; Tsarfaty, Ilan; Erez, Neta.

Elife ; 102021 06 25.

Artigo em Inglês | MEDLINE | ID: mdl-34169837

10.

Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states.

Chaligne, Ronan; Gaiti, Federico; Silverbush, Dana; Schiffman, Joshua S; Weisman, Hannah R; Kluegel, Lloyd; Gritsch, Simon; Deochand, Sunil D; Gonzalez Castro, L Nicolas; Richman, Alyssa R; Klughammer, Johanna; Biancalani, Tommaso; Muus, Christoph; Sheridan, Caroline; Alonso, Alicia; Izzo, Franco; Park, Jane; Rozenblatt-Rosen, Orit; Regev, Aviv; Suvà, Mario L; Landau, Dan A.

Nat Genet ; 53(10): 1469-1479, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34594037

11.

A systematic approach to orient the human protein-protein interaction network.

Silverbush, Dana; Sharan, Roded.

Nat Commun ; 10(1): 3015, 2019 07 09.

Artigo em Inglês | MEDLINE | ID: mdl-31289271

12.

Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules.

Silverbush, Dana; Cristea, Simona; Yanovich-Arad, Gali; Geiger, Tamar; Beerenwinkel, Niko; Sharan, Roded.

Cell Syst ; 8(5): 456-466.e5, 2019 05 22.

Artigo em Inglês | MEDLINE | ID: mdl-31103572

13.

Principles of Systems Biology, No. 31.

Cho, Hyunghoon; Berger, Bonnie; Peng, Jian; Galitzine, Cyril; Vitek, Olga; Beltran, Pierre M Jean; Cristea, Ileana M; Görtler, Franziska; Solbrig, Stefan; Wettig, Tilo; Oefner, Peter J; Spang, Rainer; Altenbuchinger, Michael; Basso, Rebecca Sarto; Hochbaum, Dorit; Vandin, Fabio; Silverbush, Dana; Cristea, Simona; Yanovich, Gali; Geiger, Tamar; Beerenwinkel, Niko; Sharan, Roded; Zhou, Zhemin; Luhmann, Nina; Alikhan, Nabil-Fareed; Achtman, Mark.

Cell Syst ; 7(2): 133-135, 2018 08 22.

Artigo em Inglês | MEDLINE | ID: mdl-30138580

14.

Cell-Specific Computational Modeling of the PIM Pathway in Acute Myeloid Leukemia.

Silverbush, Dana; Grosskurth, Shaun; Wang, Dennis; Powell, Francoise; Gottgens, Berthold; Dry, Jonathan; Fisher, Jasmin.

Cancer Res ; 77(4): 827-838, 2017 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-27965317

15.

INFERENCE OF PERSONALIZED DRUG TARGETS VIA NETWORK PROPAGATION.

Shnaps, Ortal; Perry, Eyal; Silverbush, Dana; Sharan, Roded.

Pac Symp Biocomput ; 21: 156-67, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-26776182

16.

Optimally orienting physical networks.

Silverbush, Dana; Elberfeld, Michael; Sharan, Roded.

J Comput Biol ; 18(11): 1437-48, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21999286

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