Detalhe da pesquisa
1.
Deregulation of autophagy in postmortem brains of Machado-Joseph disease patients.
Neuropathology
; 38(2): 113-124, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29218765
2.
The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice.
Acta Neuropathol
; 128(5): 705-22, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24859968
3.
Interferon ß induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice.
Brain
; 136(Pt 6): 1732-45, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23518714
4.
SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7.
Hum Mol Genet
; 19(1): 181-95, 2010 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19843541
5.
PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins.
J Cell Biol
; 174(1): 65-76, 2006 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16818720
6.
SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models.
Dis Model Mech
; 12(1)2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559154
7.
Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2.
Cell Rep
; 21(10): 2688-2695, 2017 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29212017
8.
Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.
Mol Neurodegener
; 11(1): 58, 2016 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27465358
9.
Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.
Nat Struct Mol Biol
; 21(11): 955-961, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25306109
10.
Corrigendum: Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7.
Nat Struct Mol Biol
; 22(3): 272, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25736092
11.
Polyglutamine and polyalanine expansions in ataxin7 result in different types of aggregation and levels of toxicity.
Mol Cell Neurosci
; 31(3): 438-45, 2006 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-16325416