Comparative risk assessment studies estimating the hazard posed by long-term consumption of PPCPs in river water.

This study assesses the risk due to Emerging Contaminants (ECs), present in Indian rivers - Ganga (650 million inhabitants), Yamuna (57 million inhabitants), and Musi (7,500,000 inhabitants), 13 ECs in total, have been used for risk assessment studies. Their concentrations (e.g., Fluconazole: 236950 µg/l, Ciprofloxacin: 31000 µg/l, Caffeine: 21.57 µg/l, etc.) were higher than the threshold concentrations for safe consumption (e.g. Fluconazole allowable level is 3.8 µg/l, and Ciprofloxacin allowable level is 0.51 µg/l). Three different pathways of emerging contaminants (ECs) transfer (oral water ingestion, oral fish ingestion, and dermal water contact) have been considered and the study is carried out in 2 ways: (i) deterministic and (ii) probabilistic approaches (using Monte Carlo iterative methods with 10000 simulations) with the aid of a software - Risk (version 7.5). The risk value, quantified by Hazard Quotient (HQ) is higher than the allowable limit of 1 for several compounds in the three rivers like Fluconazole (HQ = 18276.713), Ciprofloxacin (HQ = 278.675), Voriconazole (HQ = 14.578), Cetirizine (HQ = 1006.917), Moxifloxacin (HQ = 8.076), Caffeine (HQ = 55.150), and Ibuprofen (HQ = 9.503). Results show that Fluconazole and Caffeine pose the maximum risk in the rivers via the "oral pathway" that allows maximum transfer of the ECs present in the river (93% and 82% contribution to total risk). The risk values vary from nearly 25 times to 19000 times the United States Environmental Protection Agency (USEPA) threshold limit of 1 (e.g., Caffeine Infant Risk = 25.990 and Fluconazole Adult Risk = 18276.713). The most susceptible age group, from this study, is "Adults" (19-70 years old), who stand the chance of experiencing the adverse health hazards associated with prolonged over-exposure to the ECs present in the river waters. Musi has the maximum concentration of pollutants and requires immediate remediation measures. Further, both methods indicate that nearly 60-70% of the population in all the three study areas are at risk of developing health hazards associated with over-exposure to ECs regularly, making the areas inhabitable.

Long-term impacts of climate change on coastal and transitional eco-systems in India: an overview of its current status, future projections, solutions, and policies.

Urbanization and industrial development are increasing rapidly. These are accompanied by problems of population explosion, encroachment of agricultural, and construction lands, increased waste generation, effluent release, and escalated concentrations of several greenhouse gases (GHGs) and pollutants in the atmosphere. This has led to wide-scale adverse impacts. Visible effects are fluctuations in temperatures and precipitation, rising sea levels, unpredictable floods, storms and cyclones, and disruption to coastal and transitional ecosystems. In a country like India with a massive population of nearly 1.4 billion and around 420 million people dwelling on or near the coasts, this effect is pre-dominant. India has extensive coastlines on both sides that are subject to greater contact and high impact from the water bodies. The factors impacting climate change, its consequences, and future predictions must be analyzed immediately for implementing precautionary measures to ameliorate the detrimental effects. Several endemic species have been endangered as these changes have resulted in the loss of habitat and interfered with the food webs. Climatic impacts on transitional ecosystems also need to be considered to preserve the diversity of each. The cooperation of governmental, independent organizations and policymakers throughout the world is essential to control and mediate the impacts on health, agriculture, and other related sectors, the details of which have been elaborated in this review. The review analyses the trends in climatic variation with time and discusses a few extremities which have left permanent effects on the population primarily concerning the coastal - Indian scenario and its eco-systems.