Detalhe da pesquisa
1.
Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) - Part 1.
Bioorg Med Chem Lett
; 29(4): 668-673, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30554956
2.
Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty.
Bioorg Med Chem Lett
; 29(19): 126610, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31471167
3.
Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines.
Bioorg Med Chem Lett
; 29(3): 509-514, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30553738
4.
Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG).
Bioorg Med Chem Lett
; 28(19): 3168-3173, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30174152
5.
Biochemical and antiparasitic properties of inhibitors of the Plasmodium falciparum calcium-dependent protein kinase PfCDPK1.
Antimicrob Agents Chemother
; 58(10): 6032-43, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25070106
6.
Imidazopyridazines as potent inhibitors of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1): Preparation and evaluation of pyrazole linked analogues.
Bioorg Med Chem Lett
; 23(21): 6019-24, 2013 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24035097
7.
Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases.
Bioorg Med Chem Lett
; 22(23): 7169-73, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23099093
8.
A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.
Nat Commun
; 8(1): 430, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28874661