Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection.

Mills, Richard J; Humphrey, Sean J; Fortuna, Patrick R J; Lor, Mary; Foster, Simon R; Quaife-Ryan, Gregory A; Johnston, Rebecca L; Dumenil, Troy; Bishop, Cameron; Rudraraju, Rajeev; Rawle, Daniel J; Le, Thuy; Zhao, Wei; Lee, Leo; Mackenzie-Kludas, Charley; Mehdiabadi, Neda R; Halliday, Christopher; Gilham, Dean; Fu, Li; Nicholls, Stephen J; Johansson, Jan; Sweeney, Michael; Wong, Norman C W; Kulikowski, Ewelina; Sokolowski, Kamil A; Tse, Brian W C; Devilée, Lynn; Voges, Holly K; Reynolds, Liam T; Krumeich, Sophie; Mathieson, Ellen; Abu-Bonsrah, Dad; Karavendzas, Kathy; Griffen, Brendan; Titmarsh, Drew; Elliott, David A; McMahon, James; Suhrbier, Andreas; Subbarao, Kanta; Porrello, Enzo R; Smyth, Mark J; Engwerda, Christian R; MacDonald, Kelli P A; Bald, Tobias; James, David E; Hudson, James E.

Cell ; 184(8): 2167-2182.e22, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33811809

2.

Natural innate and adaptive immunity to cancer.

Vesely, Matthew D; Kershaw, Michael H; Schreiber, Robert D; Smyth, Mark J.

Annu Rev Immunol ; 29: 235-71, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-21219185

3.

The NK cell-cancer cycle: advances and new challenges in NK cell-based immunotherapies.

Bald, Tobias; Krummel, Matthew F; Smyth, Mark J; Barry, Kevin C.

Nat Immunol ; 21(8): 835-847, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32690952

4.

The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.

Ng, Susanna S; De Labastida Rivera, Fabian; Yan, Juming; Corvino, Dillon; Das, Indrajit; Zhang, Ping; Kuns, Rachel; Chauhan, Shashi Bhushan; Hou, Jiajie; Li, Xian-Yang; Frame, Teija C M; McEnroe, Benjamin A; Moore, Eilish; Na, Jinrui; Engel, Jessica A; Soon, Megan S F; Singh, Bhawana; Kueh, Andrew J; Herold, Marco J; Montes de Oca, Marcela; Singh, Siddharth Sankar; Bunn, Patrick T; Aguilera, Amy Roman; Casey, Mika; Braun, Matthias; Ghazanfari, Nazanin; Wani, Shivangi; Wang, Yulin; Amante, Fiona H; Edwards, Chelsea L; Haque, Ashraful; Dougall, William C; Singh, Om Prakash; Baxter, Alan G; Teng, Michele W L; Loukas, Alex; Daly, Norelle L; Cloonan, Nicole; Degli-Esposti, Mariapia A; Uzonna, Jude; Heath, William R; Bald, Tobias; Tey, Siok-Keen; Nakamura, Kyohei; Hill, Geoffrey R; Kumar, Rajiv; Sundar, Shyam; Smyth, Mark J; Engwerda, Christian R.

Nat Immunol ; 21(10): 1205-1218, 2020 10.

Artigo em Inglês | MEDLINE | ID: mdl-32839608

5.

Author Correction: Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cell.

Gao, Yulong; Souza-Fonseca-Guimaraes, Fernando; Bald, Tobias; Ng, Susanna S; Young, Arabella; Ngiow, Shin Foong; Rautela, Jai; Straube, Jasmin; Waddell, Nic; Blake, Stephen J; Yan, Juming; Bartholin, Laurent; Lee, Jason S; Vivier, Eric; Takeda, Kazuyoshi; Messaoudene, Meriem; Zitvogel, Laurence; Teng, Michele W L; Belz, Gabrielle T; Engwerda, Christian R; Huntington, Nicholas D; Nakamura, Kyohei; Hölzel, Michael; Smyth, Mark J.

Nat Immunol ; 25(5): 925-926, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38514890

6.

Author Correction: CIS is a potent checkpoint in NK cell-mediated tumor immunity.

Delconte, Rebecca B; Kolesnik, Tatiana B; Dagley, Laura F; Rautela, Jai; Shi, Wei; Putz, Eva M; Stannard, Kimberley; Zhang, Jian-Guo; Teh, Charis; Firth, Matt; Ushiki, Takashi; Andoniou, Christopher E; Degli-Esposti, Mariapia A; Sharp, Phillip P; Sanvitale, Caroline E; Infusini, Giuseppe; Liau, Nicholas P D; Linossi, Edmond M; Burns, Christopher J; Carotta, Sebastian; Gray, Daniel H D; Seillet, Cyril; Hutchinson, Dana S; Belz, Gabrielle T; Webb, Andrew I; Alexander, Warren S; Li, Shawn S; Bullock, Alex N; Babon, Jeffrey J; Smyth, Mark J; Nicholson, Sandra E; Huntington, Nicholas D.

Nat Immunol ; 25(2): 371-372, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38087084

7.

Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.

Ng, Susanna S; De Labastida Rivera, Fabian; Yan, Juming; Corvino, Dillon; Das, Indrajit; Zhang, Ping; Kuns, Rachel; Chauhan, Shashi Bhushan; Hou, Jiajie; Li, Xian-Yang; Frame, Teija C M; McEnroe, Benjamin A; Moore, Eilish; Na, Jinrui; Engel, Jessica A; Soon, Megan S F; Singh, Bhawana; Kueh, Andrew J; Herold, Marco J; Montes de Oca, Marcela; Singh, Siddharth Sankar; Bunn, Patrick T; Aguilera, Amy Roman; Casey, Mika; Braun, Matthias; Ghazanfari, Nazanin; Wani, Shivangi; Wang, Yulin; Amante, Fiona H; Edwards, Chelsea L; Haque, Ashraful; Dougall, William C; Singh, Om Prakash; Baxter, Alan G; Teng, Michele W L; Loukas, Alex; Daly, Norelle L; Cloonan, Nicole; Degli-Esposti, Mariapia A; Uzonna, Jude; Heath, William R; Bald, Tobias; Tey, Siok-Keen; Nakamura, Kyohei; Hill, Geoffrey R; Kumar, Rajiv; Sundar, Shyam; Smyth, Mark J; Engwerda, Christian R.

Nat Immunol ; 25(4): 716, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38360937

8.

Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells.

Gao, Yulong; Souza-Fonseca-Guimaraes, Fernando; Bald, Tobias; Ng, Susanna S; Young, Arabella; Ngiow, Shin Foong; Rautela, Jai; Straube, Jasmin; Waddell, Nic; Blake, Stephen J; Yan, Juming; Bartholin, Laurent; Lee, Jason S; Vivier, Eric; Takeda, Kazuyoshi; Messaoudene, Meriem; Zitvogel, Laurence; Teng, Michele W L; Belz, Gabrielle T; Engwerda, Christian R; Huntington, Nicholas D; Nakamura, Kyohei; Hölzel, Michael; Smyth, Mark J.

Nat Immunol ; 18(9): 1004-1015, 2017 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-28759001

9.

Natural Killers out of Thin Air.

Nakamura, Kyohei; Smyth, Mark J.

Immunity ; 52(6): 895-897, 2020 06 16.

Artigo em Inglês | MEDLINE | ID: mdl-32553176

10.

Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma.

Effern, Maike; Glodde, Nicole; Braun, Matthias; Liebing, Jana; Boll, Helena N; Yong, Michelle; Bawden, Emma; Hinze, Daniel; van den Boorn-Konijnenberg, Debby; Daoud, Mila; Aymans, Pia; Landsberg, Jennifer; Smyth, Mark J; Flatz, Lukas; Tüting, Thomas; Bald, Tobias; Gebhardt, Thomas; Hölzel, Michael.

Immunity ; 53(3): 564-580.e9, 2020 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-32750334

11.

Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8⁺ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy.

Weulersse, Marianne; Asrir, Assia; Pichler, Andrea C; Lemaitre, Lea; Braun, Matthias; Carrié, Nadège; Joubert, Marie-Véronique; Le Moine, Marie; Do Souto, Laura; Gaud, Guillaume; Das, Indrajit; Brauns, Elisa; Scarlata, Clara M; Morandi, Elena; Sundarrajan, Ashmitha; Cuisinier, Marine; Buisson, Laure; Maheo, Sabrina; Kassem, Sahar; Agesta, Arantxa; Pérès, Michaël; Verhoeyen, Els; Martinez, Alejandra; Mazieres, Julien; Dupré, Loïc; Gossye, Thomas; Pancaldi, Vera; Guillerey, Camille; Ayyoub, Maha; Dejean, Anne S; Saoudi, Abdelhadi; Goriely, Stanislas; Avet-Loiseau, Hervé; Bald, Tobias; Smyth, Mark J; Martinet, Ludovic.

Immunity ; 53(4): 824-839.e10, 2020 10 13.

Artigo em Inglês | MEDLINE | ID: mdl-33053331

12.

CD155 on Tumor Cells Drives Resistance to Immunotherapy by Inducing the Degradation of the Activating Receptor CD226 in CD8⁺ T Cells.

Braun, Matthias; Aguilera, Amelia Roman; Sundarrajan, Ashmitha; Corvino, Dillon; Stannard, Kimberley; Krumeich, Sophie; Das, Indrajit; Lima, Luize G; Meza Guzman, Lizeth G; Li, Kunlun; Li, Rui; Salim, Nazhifah; Jorge, Maria Villancanas; Ham, Sunyoung; Kelly, Gabrielle; Vari, Frank; Lepletier, Ailin; Raghavendra, Ashwini; Pearson, Sally; Madore, Jason; Jacquelin, Sebastien; Effern, Maike; Quine, Brodie; Koufariotis, Lambros T; Casey, Mika; Nakamura, Kyohei; Seo, Eun Y; Hölzel, Michael; Geyer, Matthias; Kristiansen, Glen; Taheri, Touraj; Ahern, Elizabeth; Hughes, Brett G M; Wilmott, James S; Long, Georgina V; Scolyer, Richard A; Batstone, Martin D; Landsberg, Jennifer; Dietrich, Dimo; Pop, Oltin T; Flatz, Lukas; Dougall, William C; Veillette, André; Nicholson, Sandra E; Möller, Andreas; Johnston, Robert J; Martinet, Ludovic; Smyth, Mark J; Bald, Tobias.

Immunity ; 53(4): 805-823.e15, 2020 10 13.

Artigo em Inglês | MEDLINE | ID: mdl-33053330

13.

Targeting natural killer cells in cancer immunotherapy.

Guillerey, Camille; Huntington, Nicholas D; Smyth, Mark J.

Nat Immunol ; 17(9): 1025-36, 2016 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-27540992

14.

CIS is a potent checkpoint in NK cell-mediated tumor immunity.

Delconte, Rebecca B; Kolesnik, Tatiana B; Dagley, Laura F; Rautela, Jai; Shi, Wei; Putz, Eva M; Stannard, Kimberley; Zhang, Jian-Guo; Teh, Charis; Firth, Matt; Ushiki, Takashi; Andoniou, Christopher E; Degli-Esposti, Mariapia A; Sharp, Phillip P; Sanvitale, Caroline E; Infusini, Giuseppe; Liau, Nicholas P D; Linossi, Edmond M; Burns, Christopher J; Carotta, Sebastian; Gray, Daniel H D; Seillet, Cyril; Hutchinson, Dana S; Belz, Gabrielle T; Webb, Andrew I; Alexander, Warren S; Li, Shawn S; Bullock, Alex N; Babon, Jeffery J; Smyth, Mark J; Nicholson, Sandra E; Huntington, Nicholas D.

Nat Immunol ; 17(7): 816-24, 2016 07.

Artigo em Inglês | MEDLINE | ID: mdl-27213690

15.

The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions.

Chan, Christopher J; Martinet, Ludovic; Gilfillan, Susan; Souza-Fonseca-Guimaraes, Fernando; Chow, Melvyn T; Town, Liam; Ritchie, David S; Colonna, Marco; Andrews, Daniel M; Smyth, Mark J.

Nat Immunol ; 15(5): 431-8, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24658051

16.

Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy.

Glodde, Nicole; Bald, Tobias; van den Boorn-Konijnenberg, Debby; Nakamura, Kyohei; O'Donnell, Jake S; Szczepanski, Sabrina; Brandes, Maria; Eickhoff, Sarah; Das, Indrajit; Shridhar, Naveen; Hinze, Daniel; Rogava, Meri; van der Sluis, Tetje C; Ruotsalainen, Janne J; Gaffal, Evelyn; Landsberg, Jennifer; Ludwig, Kerstin U; Wilhelm, Christoph; Riek-Burchardt, Monika; Müller, Andreas J; Gebhardt, Christoffer; Scolyer, Richard A; Long, Georgina V; Janzen, Viktor; Teng, Michele W L; Kastenmüller, Wolfgang; Mazzone, Massimiliano; Smyth, Mark J; Tüting, Thomas; Hölzel, Michael.

Immunity ; 47(4): 789-802.e9, 2017 10 17.

Artigo em Inglês | MEDLINE | ID: mdl-29045907

17.

ATP and cancer immunosurveillance.

Kepp, Oliver; Bezu, Lucillia; Yamazaki, Takahiro; Di Virgilio, Francesco; Smyth, Mark J; Kroemer, Guido; Galluzzi, Lorenzo.

EMBO J ; 40(13): e108130, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-34121201

18.

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

Delconte, Rebecca B; Shi, Wei; Sathe, Priyanka; Ushiki, Takashi; Seillet, Cyril; Minnich, Martina; Kolesnik, Tatiana B; Rankin, Lucille C; Mielke, Lisa A; Zhang, Jian-Guo; Busslinger, Meinrad; Smyth, Mark J; Hutchinson, Dana S; Nutt, Stephen L; Nicholson, Sandra E; Alexander, Warren S; Corcoran, Lynn M; Vivier, Eric; Belz, Gabrielle T; Carotta, Sebastian; Huntington, Nicholas D.

Immunity ; 44(1): 103-115, 2016 Jan 19.

Artigo em Inglês | MEDLINE | ID: mdl-26795246

19.

Cytokine-driven role of Srebps in killer cell metabolism.

Guillerey, Camille; Smyth, Mark J.

Nat Immunol ; 18(11): 1183-1184, 2017 10 18.

Artigo em Inglês | MEDLINE | ID: mdl-29044236

20.

Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells.

Andrews, Daniel M; Sullivan, Lucy C; Baschuk, Nikola; Chan, Christopher J; Berry, Richard; Cotterell, Claire L; Lin, Jie; Halse, Heloise; Watt, Sally V; Poursine-Laurent, Jennifer; Wang, Chyung-Ru; Scalzo, Anthony A; Yokoyama, Wayne M; Rossjohn, Jamie; Brooks, Andrew G; Smyth, Mark J.

Nat Immunol ; 13(12): 1171-7, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23142773

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