Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Croquemort elicits activation of the immune deficiency pathway in ticks.

O'Neal, Anya J; Singh, Nisha; Rolandelli, Agustin; Laukaitis, Hanna J; Wang, Xiaowei; Shaw, Dana K; Young, Brianna D; Narasimhan, Sukanya; Dutta, Shraboni; Snyder, Greg A; Samaddar, Sourabh; Marnin, Liron; Butler, L Rainer; Mendes, M Tays; Cabrera Paz, Francy E; Valencia, Luisa M; Sundberg, Eric J; Fikrig, Erol; Pal, Utpal; Weber, David J; Pedra, Joao H F.

Proc Natl Acad Sci U S A ; 120(20): e2208673120, 2023 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-37155900

2.

The structure of NAD⁺ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.

Klontz, Erik; Obi, Juliet O; Wang, Yajing; Glendening, Gabrielle; Carr, Jahid; Tsibouris, Constantine; Buddula, Sahthi; Nallar, Shreeram; Soares, Alexei S; Beckett, Dorothy; Redzic, Jasmina S; Eisenmesser, Elan; Palm, Cheyenne; Schmidt, Katrina; Scudder, Alexis H; Obiorah, Trinity; Essuman, Kow; Milbrandt, Jeffrey; Diantonio, Aaron; Ray, Krishanu; Snyder, Michelle L D; Deredge, Daniel; Snyder, Greg A.

J Biol Chem ; 299(11): 105290, 2023 11.

Artigo em Inglês | MEDLINE | ID: mdl-37758001

3.

Emerging of a SARS-CoV-2 viral strain with a deletion in nsp1.

Benedetti, Francesca; Snyder, Greg A; Giovanetti, Marta; Angeletti, Silvia; Gallo, Robert C; Ciccozzi, Massimo; Zella, Davide.

J Transl Med ; 18(1): 329, 2020 08 31.

Artigo em Inglês | MEDLINE | ID: mdl-32867854

4.

Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain.

Mistry, Pragnesh; Laird, Michelle H W; Schwarz, Ryan S; Greene, Shannon; Dyson, Tristan; Snyder, Greg A; Xiao, Tsan Sam; Chauhan, Jay; Fletcher, Steven; Toshchakov, Vladimir Y; MacKerell, Alexander D; Vogel, Stefanie N.

Proc Natl Acad Sci U S A ; 112(17): 5455-60, 2015 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-25870276

5.

Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.

Trastoy, Beatriz; Lomino, Joseph V; Pierce, Brian G; Carter, Lester G; Günther, Sebastian; Giddens, John P; Snyder, Greg A; Weiss, Thomas M; Weng, Zhiping; Wang, Lai-Xi; Sundberg, Eric J.

Proc Natl Acad Sci U S A ; 111(18): 6714-9, 2014 May 06.

Artigo em Inglês | MEDLINE | ID: mdl-24753590

6.

The Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.

Wang, Xiaowei; Shaw, Dana K; Sakhon, Olivia S; Snyder, Greg A; Sundberg, Eric J; Santambrogio, Laura; Sutterwala, Fayyaz S; Dumler, J Stephen; Shirey, Kari Ann; Perkins, Darren J; Richard, Katharina; Chagas, Andrezza C; Calvo, Eric; Kopecký, Jan; Kotsyfakis, Michail; Pedra, Joao H F.

Infect Immun ; 84(6): 1796-1805, 2016 06.

Artigo em Inglês | MEDLINE | ID: mdl-27045038

7.

Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli.

Snyder, Greg A; Cirl, Christine; Jiang, Jiansheng; Chen, Kang; Waldhuber, Anna; Smith, Patrick; Römmler, Franziska; Snyder, Nathaniel; Fresquez, Theresa; Dürr, Susanne; Tjandra, Nico; Miethke, Thomas; Xiao, Tsan Sam.

Proc Natl Acad Sci U S A ; 110(17): 6985-90, 2013 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-23569230

8.

Crystal structures of the Toll/Interleukin-1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry.

Snyder, Greg A; Deredge, Daniel; Waldhuber, Anna; Fresquez, Theresa; Wilkins, David Z; Smith, Patrick T; Durr, Susi; Cirl, Christine; Jiang, Jiansheng; Jennings, William; Luchetti, Timothy; Snyder, Nathaniel; Sundberg, Eric J; Wintrode, Patrick; Miethke, Thomas; Xiao, T Sam.

J Biol Chem ; 289(2): 669-79, 2014 Jan 10.

Artigo em Inglês | MEDLINE | ID: mdl-24275656

9.

Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins.

Piepenbrink, Kurt H; Maldarelli, Grace A; de la Peña, Claudia F Martinez; Mulvey, George L; Snyder, Greg A; De Masi, Leon; von Rosenvinge, Erik C; Günther, Sebastian; Armstrong, Glen D; Donnenberg, Michael S; Sundberg, Eric J.

J Biol Chem ; 289(7): 4334-45, 2014 Feb 14.

Artigo em Inglês | MEDLINE | ID: mdl-24362261

10.

The tick salivary protein sialostatin L2 inhibits caspase-1-mediated inflammation during Anaplasma phagocytophilum infection.

Chen, Gang; Wang, Xiaowei; Severo, Maiara S; Sakhon, Olivia S; Sohail, Mohammad; Brown, Lindsey J; Sircar, Mayukh; Snyder, Greg A; Sundberg, Eric J; Ulland, Tyler K; Olivier, Alicia K; Andersen, John F; Zhou, Yi; Shi, Guo-Ping; Sutterwala, Fayyaz S; Kotsyfakis, Michail; Pedra, Joao H F.

Infect Immun ; 82(6): 2553-64, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24686067

11.

Discordant Antigenic Properties of Soluble and Virion SARS-CoV-2 Spike Proteins.

Kumar, Sameer; Dasgupta, Souradip; Sajadi, Mohammad M; Snyder, Greg A; DeVico, Anthony L; Ray, Krishanu.

Viruses ; 16(3)2024 03 06.

Artigo em Inglês | MEDLINE | ID: mdl-38543772

12.

Structural determination of Rickettsia lipid A without chemical extraction confirms shorter acyl chains in later-evolving spotted fever group pathogens.

Yang, Hyojik; Verhoeve, Victoria I; Chandler, Courtney E; Nallar, Shreeram; Snyder, Greg A; Ernst, Robert K; Gillespie, Joseph J.

mSphere ; 9(2): e0060923, 2024 Feb 28.

Artigo em Inglês | MEDLINE | ID: mdl-38259062

13.

R753Q polymorphism inhibits Toll-like receptor (TLR) 2 tyrosine phosphorylation, dimerization with TLR6, and recruitment of myeloid differentiation primary response protein 88.

Xiong, Yanbao; Song, Chang; Snyder, Greg A; Sundberg, Eric J; Medvedev, Andrei E.

J Biol Chem ; 287(45): 38327-37, 2012 Nov 02.

Artigo em Inglês | MEDLINE | ID: mdl-22992740

14.

Two-photon fluorescence lifetime imaging microscopy of NADH metabolism in HIV-1 infected cells and tissues.

Snyder, Greg A; Kumar, Sameer; Lewis, George K; Ray, Krishanu.

Front Immunol ; 14: 1213180, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37662898

15.

Structural determination of Rickettsia lipid A without chemical extraction confirms shorter acyl chains in later-evolving Spotted Fever Group pathogens.

Yang, Hyojik; Verhoeve, Victoria I; Chandler, Courtney E; Nallar, Shreeram; Snyder, Greg A; Ernst, Robert K; Gillespie, Joseph J.

bioRxiv ; 2023 Jul 06.

Artigo em Inglês | MEDLINE | ID: mdl-37461656

16.

Development of an anti-Pseudomonas aeruginosa therapeutic monoclonal antibody WVDC-5244.

Horspool, Alexander M; Sen-Kilic, Emel; Malkowski, Aaron C; Breslow, Scott L; Mateu-Borras, Margalida; Hudson, Matthew S; Nunley, Mason A; Elliott, Sean; Ray, Krishanu; Snyder, Greg A; Miller, Sarah Jo; Kang, Jason; Blackwood, Catherine B; Weaver, Kelly L; Witt, William T; Huckaby, Annalisa B; Pyles, Gage M; Clark, Tammy; Al Qatarneh, Saif; Lewis, George K; Damron, F Heath; Barbier, Mariette.

Front Cell Infect Microbiol ; 13: 1117844, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37124031

17.

Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor.

Fields, James K; Kihn, Kyle; Birkedal, Gabriel S; Klontz, Erik H; Sjöström, Kjell; Günther, Sebastian; Beadenkopf, Robert; Forsberg, Göran; Liberg, David; Snyder, Greg A; Deredge, Daniel; Sundberg, Eric J.

Front Immunol ; 12: 779100, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-35003094

18.

Cobbling Together the Myddosome.

Snyder, Michelle L D; Snyder, Greg A.

Structure ; 28(6): 598-600, 2020 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-32492411

19.

Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.

Klontz, Erik H; Li, Chao; Kihn, Kyle; Fields, James K; Beckett, Dorothy; Snyder, Greg A; Wintrode, Patrick L; Deredge, Daniel; Wang, Lai-Xi; Sundberg, Eric J.

Nat Commun ; 11(1): 6204, 2020 12 04.

Artigo em Inglês | MEDLINE | ID: mdl-33277506

20.

Infection-derived lipids elicit an immune deficiency circuit in arthropods.

Shaw, Dana K; Wang, Xiaowei; Brown, Lindsey J; Chávez, Adela S Oliva; Reif, Kathryn E; Smith, Alexis A; Scott, Alison J; McClure, Erin E; Boradia, Vishant M; Hammond, Holly L; Sundberg, Eric J; Snyder, Greg A; Liu, Lei; DePonte, Kathleen; Villar, Margarita; Ueti, Massaro W; de la Fuente, José; Ernst, Robert K; Pal, Utpal; Fikrig, Erol; Pedra, Joao H F.

Nat Commun ; 8: 14401, 2017 02 14.

Artigo em Inglês | MEDLINE | ID: mdl-28195158

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