Detalhe da pesquisa
1.
Oxidized cholesteryl ester induces exocytosis of dysfunctional lysosomes in lipidotic macrophages.
Traffic
; 24(7): 284-307, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37129279
2.
Cholesteryl hemiazelate causes lysosome dysfunction impacting vascular smooth muscle cell homeostasis.
J Cell Sci
; 135(5)2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34528688
3.
Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation.
J Lipid Res
; 64(9): 100419, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37482218
4.
Diels-Alder Cycloaddition Reactions in Sustainable Media.
Molecules
; 27(4)2022 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35209094
5.
Synthesis of 5H-chromeno[3,4-b]pyridines via DABCO-catalyzed [3 + 3] annulation of 3-nitro-2H-chromenes and allenoates.
Org Biomol Chem
; 19(44): 9711-9722, 2021 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34726223
6.
Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(2): 210-220, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27793708
7.
Chiral hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: the search for selective p53-activating agents for colorectal cancer therapy.
RSC Med Chem
; 15(5): 1652-1663, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38784460
8.
Thiazolo[3,4-b]indazole-2,2-dioxides as masked extended dipoles: pericyclic reactions of benzodiazafulvenium methides.
J Org Chem
; 78(2): 628-37, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23215255
9.
Cholesteryl Hemiazelate Present in Cardiovascular Disease Patients Causes Lysosome Dysfunction in Murine Fibroblasts.
Cells
; 12(24)2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38132146
10.
Synthesis and structure-activity relationships of new chiral spiro-ß-lactams highly active against HIV-1 and Plasmodium.
Eur J Med Chem
; 219: 113439, 2021 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887681
11.
A selective p53 activator and anticancer agent to improve colorectal cancer therapy.
Cell Rep
; 35(2): 108982, 2021 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852837
12.
Spiro-Lactams as Novel Antimicrobial Agents.
Curr Top Med Chem
; 20(2): 140-152, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31702503
13.
Targeting triple-negative breast cancer cells with 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles.
Eur J Med Chem
; 79: 273-81, 2014 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24747064
14.
Chiral 6,7-bis(hydroxymethyl)-1H,3H-pyrrolo[1,2-c]thiazoles with anti-breast cancer properties.
Eur J Med Chem
; 60: 254-62, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23313634
15.
Chiral 6-hydroxymethyl-1H,3H-pyrrolo[1,2-c]thiazoles: novel antitumor DNA monoalkylating agents.
Eur J Med Chem
; 45(10): 4676-81, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20705366
16.
Chemistry of diazafulvenium methides in the synthesis of functionalized pyrazoles.
J Org Chem
; 72(12): 4406-15, 2007 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17489636
17.
N-Vinyl- and C-vinylpyrroles from azafulvenium methides. flash vacuum pyrolysis route to 5-Oxo-5H-pyrrolizines and 1-azabenzo[f]azulenes.
J Org Chem
; 70(17): 6629-38, 2005 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16095280
18.
Synthesis of chiral pyrrolo[1,2-c]thiazoles via intramolecular dipolar cycloaddition of münchnones: an interesting rearrangement to pyrrolo[1,2-c]thiazines.
J Org Chem
; 67(12): 4045-54, 2002 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12054937