Detalhe da pesquisa
1.
Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
J Infect Dis
; 220(11): 1761-1770, 2019 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31549155
2.
A Randomized Trial Evaluating the Prophylactic Activity of DSM265 Against Preerythrocytic Plasmodium falciparum Infection During Controlled Human Malarial Infection by Mosquito Bites and Direct Venous Inoculation.
J Infect Dis
; 217(5): 693-702, 2018 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29216395
3.
Developmental differences in stress responding after repeated underwater trauma exposures in rats.
Stress
; 21(3): 267-273, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29451058
4.
Comparison of Anti-Xa Activity in Patients Receiving Apixaban or Rivaroxaban.
Ann Pharmacother
; 52(3): 251-256, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29047306
5.
Corrigendum to: Determination of Cytochrome P450 Isoenzyme 2D6 (CYP2D6) Genotypes and Pharmacogenomic Impact on Primaquine Metabolism in an Active-Duty US Military Population.
J Infect Dis
; 221(7): 1204, 2020 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31773155
6.
Differential cytochrome P450 2D metabolism alters tafenoquine pharmacokinetics.
Antimicrob Agents Chemother
; 59(7): 3864-9, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25870069
7.
Differential CYP 2D6 metabolism alters primaquine pharmacokinetics.
Antimicrob Agents Chemother
; 59(4): 2380-7, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25645856
8.
Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds.
Malar J
; 13: 2, 2014 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24386891
9.
The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models.
Eur J Drug Metab Pharmacokinet
; 39(4): 231-6, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24705994
10.
CYP450 phenotyping and metabolite identification of quinine by accurate mass UPLC-MS analysis: a possible metabolic link to blackwater fever.
Malar J
; 12: 214, 2013 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-23800033
11.
The metabolism of primaquine to its active metabolite is dependent on CYP 2D6.
Malar J
; 12: 212, 2013 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23782898
12.
Prolonged protection provided by a single dose of atovaquone-proguanil for the chemoprophylaxis of Plasmodium falciparum malaria in a human challenge model.
Clin Infect Dis
; 54(2): 232-9, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22052893
13.
CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.
Malar J
; 11: 259, 2012 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22856549
14.
Primaquine failure and cytochrome P-450 2D6 in Plasmodium vivax malaria.
N Engl J Med
; 369(14): 1381-2, 2013 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24088113
15.
Response and recovery of endocrine, behavioral, and neuronal morphology outcomes after different traumatic stressor exposures in male rats.
Psychoneuroendocrinology
; 133: 105394, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34474197
16.
Controlled human malaria infection with a clone of Plasmodium vivax with high-quality genome assembly.
JCI Insight
; 6(23)2021 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34609964
17.
Saccharomyces boulardii CNCM I-745 probiotic does not alter the pharmacokinetics of amoxicillin.
Drug Metab Pers Ther
; 35(1)2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32134728
18.
Role of specific cytochrome P450 isoforms in the conversion of phenoxypropoxybiguanide analogs in human liver microsomes to potent antimalarial dihydrotriazines.
Drug Metab Dispos
; 36(2): 380-5, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18006651
19.
Comparison of MDCK-MDR1 and Caco-2 cell based permeability assays for anti-malarial drug screening and drug investigations.
J Pharmacol Toxicol Methods
; 70(2): 188-94, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25150934