Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Long non-coding RNAs: definitions, functions, challenges and recommendations.

Mattick, John S; Amaral, Paulo P; Carninci, Piero; Carpenter, Susan; Chang, Howard Y; Chen, Ling-Ling; Chen, Runsheng; Dean, Caroline; Dinger, Marcel E; Fitzgerald, Katherine A; Gingeras, Thomas R; Guttman, Mitchell; Hirose, Tetsuro; Huarte, Maite; Johnson, Rory; Kanduri, Chandrasekhar; Kapranov, Philipp; Lawrence, Jeanne B; Lee, Jeannie T; Mendell, Joshua T; Mercer, Timothy R; Moore, Kathryn J; Nakagawa, Shinichi; Rinn, John L; Spector, David L; Ulitsky, Igor; Wan, Yue; Wilusz, Jeremy E; Wu, Mian.

Nat Rev Mol Cell Biol ; 24(6): 430-447, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-36596869

2.

Chromatin meets its organizers.

Bodnar, Megan S; Spector, David L.

Cell ; 153(6): 1187-9, 2013 Jun 06.

Artigo em Inglês | MEDLINE | ID: mdl-23746835

3.

POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer.

Huang, Yu-Han; Klingbeil, Olaf; He, Xue-Yan; Wu, Xiaoli S; Arun, Gayatri; Lu, Bin; Somerville, Tim D D; Milazzo, Joseph P; Wilkinson, John E; Demerdash, Osama E; Spector, David L; Egeblad, Mikala; Shi, Junwei; Vakoc, Christopher R.

Genes Dev ; 32(13-14): 915-928, 2018 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-29945888

4.

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.

Arun, Gayatri; Diermeier, Sarah; Akerman, Martin; Chang, Kung-Chi; Wilkinson, J Erby; Hearn, Stephen; Kim, Youngsoo; MacLeod, A Robert; Krainer, Adrian R; Norton, Larry; Brogi, Edi; Egeblad, Mikala; Spector, David L.

Genes Dev ; 30(1): 34-51, 2016 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-26701265

5.

Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing.

Aganezov, Sergey; Goodwin, Sara; Sherman, Rachel M; Sedlazeck, Fritz J; Arun, Gayatri; Bhatia, Sonam; Lee, Isac; Kirsche, Melanie; Wappel, Robert; Kramer, Melissa; Kostroff, Karen; Spector, David L; Timp, Winston; McCombie, W Richard; Schatz, Michael C.

Genome Res ; 30(9): 1258-1273, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32887686

6.

Chromatin dynamics and gene positioning.

Kumaran, R Ileng; Thakar, Rajika; Spector, David L.

Cell ; 132(6): 929-34, 2008 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-18358806

7.

3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA.

Wilusz, Jeremy E; Freier, Susan M; Spector, David L.

Cell ; 135(5): 919-32, 2008 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-19041754

8.

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation.

Shi, Junwei; Whyte, Warren A; Zepeda-Mendoza, Cinthya J; Milazzo, Joseph P; Shen, Chen; Roe, Jae-Seok; Minder, Jessica L; Mercan, Fatih; Wang, Eric; Eckersley-Maslin, Melanie A; Campbell, Amy E; Kawaoka, Shinpei; Shareef, Sarah; Zhu, Zhu; Kendall, Jude; Muhar, Matthias; Haslinger, Christian; Yu, Ming; Roeder, Robert G; Wigler, Michael H; Blobel, Gerd A; Zuber, Johannes; Spector, David L; Young, Richard A; Vakoc, Christopher R.

Genes Dev ; 27(24): 2648-62, 2013 Dec 15.

Artigo em Inglês | MEDLINE | ID: mdl-24285714

9.

MALAT1 long non-coding RNA and breast cancer.

Arun, Gayatri; Spector, David L.

RNA Biol ; 16(6): 860-863, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-30874469

10.

Regulation of the ESC transcriptome by nuclear long noncoding RNAs.

Bergmann, Jan H; Li, Jingjing; Eckersley-Maslin, Mélanie A; Rigo, Frank; Freier, Susan M; Spector, David L.

Genome Res ; 25(9): 1336-46, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26048247

11.

Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage.

Oda, Hisanobu; Hübner, Michael R; Beck, David B; Vermeulen, Michiel; Hurwitz, Jerard; Spector, David L; Reinberg, Danny.

Mol Cell ; 40(3): 364-76, 2010 Nov 12.

Artigo em Inglês | MEDLINE | ID: mdl-21035370

12.

Random monoallelic expression: regulating gene expression one allele at a time.

Eckersley-Maslin, Mélanie A; Spector, David L.

Trends Genet ; 30(6): 237-44, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24780084

13.

Long noncoding RNAs: functional surprises from the RNA world.

Wilusz, Jeremy E; Sunwoo, Hongjae; Spector, David L.

Genes Dev ; 23(13): 1494-504, 2009 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-19571179

14.

Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2.

Zepeda-Mendoza, Cinthya J; Mukhopadhyay, Swagatam; Wong, Emily S; Harder, Nathalie; Splinter, Erik; de Wit, Elzo; Eckersley-Maslin, Melanie A; Ried, Thomas; Eils, Roland; Rohr, Karl; Mills, Alea; de Laat, Wouter; Flicek, Paul; Sengupta, Anirvan M; Spector, David L.

BMC Genomics ; 16: 982, 2015 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-26589460

15.

Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA.

Bell, Robert D; Long, Xiaochun; Lin, Mingyan; Bergmann, Jan H; Nanda, Vivek; Cowan, Sarah L; Zhou, Qian; Han, Yu; Spector, David L; Zheng, Deyou; Miano, Joseph M.

Arterioscler Thromb Vasc Biol ; 34(6): 1249-59, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24578380

16.

Receptor-mediated delivery of engineered nucleases for genome modification.

Chen, Zhong; Jaafar, Lahcen; Agyekum, Davies G; Xiao, Haiyan; Wade, Marlene F; Kumaran, R Ileng; Spector, David L; Bao, Gang; Porteus, Matthew H; Dynan, William S; Meiler, Steffen E.

Nucleic Acids Res ; 41(19): e182, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23956220

17.

Biogenesis and function of nuclear bodies.

Mao, Yuntao S; Zhang, Bin; Spector, David L.

Trends Genet ; 27(8): 295-306, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21680045

18.

A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression.

Bernard, Delphine; Prasanth, Kannanganattu V; Tripathi, Vidisha; Colasse, Sabrina; Nakamura, Tetsuya; Xuan, Zhenyu; Zhang, Michael Q; Sedel, Frédéric; Jourdren, Laurent; Coulpier, Fanny; Triller, Antoine; Spector, David L; Bessis, Alain.

EMBO J ; 29(18): 3082-93, 2010 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-20729808

19.

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.

Dimitrova, Nadya; Chen, Yi-Chun M; Spector, David L; de Lange, Titia.

Nature ; 456(7221): 524-8, 2008 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-18931659

20.

Four amino acids guide the assembly or disassembly of Arabidopsis histone H3.3-containing nucleosomes.

Shi, Leilei; Wang, Jing; Hong, Fang; Spector, David L; Fang, Yuda.

Proc Natl Acad Sci U S A ; 108(26): 10574-8, 2011 Jun 28.

Artigo em Inglês | MEDLINE | ID: mdl-21670303

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