Detalhe da pesquisa
1.
Pharmacology of basimglurant (RO4917523, RG7090), a unique metabotropic glutamate receptor 5 negative allosteric modulator in clinical development for depression.
J Pharmacol Exp Ther
; 353(1): 213-33, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25665805
2.
European clinical network: autism spectrum disorder assessments and patient characterisation.
Eur Child Adolesc Psychiatry
; 24(8): 985-95, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25471824
3.
Differential effects of diazepam and MPEP on habituation and neuro-behavioural processes in inbred mice.
Behav Brain Funct
; 8: 30, 2012 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22686184
4.
Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity.
Amyotroph Lateral Scler
; 13(5): 418-29, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22871074
5.
Interindividual Differences in Cortical Thickness and Their Genomic Underpinnings in Autism Spectrum Disorder.
Am J Psychiatry
; 179(3): 242-254, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503340
6.
CTEP: a novel, potent, long-acting, and orally bioavailable metabotropic glutamate receptor 5 inhibitor.
J Pharmacol Exp Ther
; 339(2): 474-86, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21849627
7.
Imbalanced social-communicative and restricted repetitive behavior subtypes of autism spectrum disorder exhibit different neural circuitry.
Commun Biol
; 4(1): 574, 2021 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33990680
8.
Rational design of novel pyrrolidine derivatives as orally active neurokinin-3 receptor antagonists.
Bioorg Med Chem Lett
; 20(22): 6735-8, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20850972
9.
Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands.
Bioorg Med Chem Lett
; 20(11): 3405-8, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20430616
10.
Transcriptome signatures from discordant sibling pairs reveal changes in peripheral blood immune cell composition in Autism Spectrum Disorder.
Transl Psychiatry
; 10(1): 106, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32291385
11.
Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project.
Mol Autism
; 11(1): 17, 2020 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32087753
12.
Investigating the factors underlying adaptive functioning in autism in the EU-AIMS Longitudinal European Autism Project.
Autism Res
; 12(4): 645-657, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30741482
13.
Reproducibility via coordinated standardization: a multi-center study in a Shank2 genetic rat model for Autism Spectrum Disorders.
Sci Rep
; 9(1): 11602, 2019 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31406134
14.
Altered Connectivity Between Cerebellum, Visual, and Sensory-Motor Networks in Autism Spectrum Disorder: Results from the EU-AIMS Longitudinal European Autism Project.
Biol Psychiatry Cogn Neurosci Neuroimaging
; 4(3): 260-270, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30711508
15.
Patients with autism spectrum disorders display reproducible functional connectivity alterations.
Sci Transl Med
; 11(481)2019 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30814340
16.
Me-talnetant and osanetant interact within overlapping but not identical binding pockets in the human tachykinin neurokinin 3 receptor transmembrane domains.
Mol Pharmacol
; 73(6): 1736-50, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18308898
17.
mGluR5 antagonists: discovery, characterization and drug development.
Curr Opin Drug Discov Devel
; 11(5): 655-65, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18729017
18.
Opinion: NK3 receptor antagonists: the next generation of antipsychotics?
Nat Rev Drug Discov
; 4(12): 967-75, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16341062
19.
Glutamate and GABA in autism spectrum disorder-a translational magnetic resonance spectroscopy study in man and rodent models.
Transl Psychiatry
; 8(1): 106, 2018 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29802263
20.
EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort.
Mol Autism
; 9: 26, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29682271