Detalhe da pesquisa
1.
Structures and kinetics of Thermotoga maritima MetY reveal new insights into the predominant sulfurylation enzyme of bacterial methionine biosynthesis.
J Biol Chem
; 296: 100797, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019879
2.
The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.
J Biol Chem
; 294(35): 13158-13170, 2019 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31315931
3.
Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A.
Org Biomol Chem
; 17(16): 3902-3913, 2019 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30941386
4.
Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.
J Biol Chem
; 291(38): 19873-87, 2016 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27474741
5.
Elongation of the Poly-γ-glutamate Tail of F420 Requires Both Domains of the F420:γ-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis.
J Biol Chem
; 291(13): 6882-94, 2016 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26861878
6.
Autocatalytically generated Thr-Gln ester bond cross-links stabilize the repetitive Ig-domain shaft of a bacterial cell surface adhesin.
Proc Natl Acad Sci U S A
; 111(4): 1367-72, 2014 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24344302
7.
Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.
Angew Chem Int Ed Engl
; 55(28): 7930-3, 2016 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27145301
8.
Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed.
J Struct Biol
; 192(3): 539-544, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26522274
9.
Self-generated covalent cross-links in the cell-surface adhesins of Gram-positive bacteria.
Biochem Soc Trans
; 43(5): 787-94, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26517883
10.
Preparation of truncated orf virus entry fusion complex proteins by chemical synthesis.
J Pept Sci
; 20(6): 398-405, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24652714
11.
The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages.
Nucleic Acids Res
; 40(12): 5731-8, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22373921
12.
Poly-γ-glutamylation of biomolecules.
Nat Commun
; 15(1): 1310, 2024 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38346985
13.
Amino-acid substitutions at the domain interface affect substrate and allosteric inhibitor binding in α-isopropylmalate synthase from Mycobacterium tuberculosis.
Biochem Biophys Res Commun
; 433(2): 249-54, 2013 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23500460
14.
Discovery and characterisation of hydrazines as inhibitors of the immune suppressive enzyme, indoleamine 2,3-dioxygenase 1 (IDO1).
Bioorg Med Chem
; 21(24): 7595-603, 2013 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24262887
15.
Domain structure and cross-linking in a giant adhesin from the Mobiluncus mulieris bacterium.
Acta Crystallogr D Struct Biol
; 79(Pt 11): 971-979, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37860959
16.
A Portable and Disposable Electrochemical Sensor Utilizing Laser-Scribed Graphene for Rapid SARS-CoV-2 Detection.
Biosensors (Basel)
; 14(1)2023 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38248387
17.
Removal of the C-terminal regulatory domain of α-isopropylmalate synthase disrupts functional substrate binding.
Biochemistry
; 51(11): 2289-97, 2012 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22352945
18.
Structure of AKR1C3 with 3-phenoxybenzoic acid bound.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 4): 409-13, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22505408
19.
Cloning, expression, purification, crystallization and preliminary X-ray studies of the C-terminal domain of Rv3262 (FbiB) from Mycobacterium tuberculosis.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 10): 1274-7, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22102046
20.
Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs.
Oncol Ther
; 9(2): 541-556, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34159519