Detalhe da pesquisa
1.
Bile Acid Tethered Docetaxel-Based Nanomicelles Mitigate Tumor Progression through Epigenetic Changes.
Angew Chem Int Ed Engl
; 60(10): 5394-5399, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33258265
2.
Tethering of Chemotherapeutic Drug/Imaging Agent to Bile Acid-Phospholipid Increases the Efficacy and Bioavailability with Reduced Hepatotoxicity.
Bioconjug Chem
; 28(12): 2942-2953, 2017 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29083862
3.
Molecular Self-Assembly of Bile Acid-Phospholipids Controls the Delivery of Doxorubicin and Mice Survivability.
Mol Pharm
; 14(8): 2649-2659, 2017 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28665132
4.
Continuous evolution of compact protein degradation tags regulated by selective molecular glues.
Science
; 383(6688): eadk4422, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38484051
5.
Proteolysis-targeting chimeras with reduced off-targets.
Nat Chem
; 16(2): 218-228, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110475
6.
Design, synthesis, and mechanistic investigations of bile acid-tamoxifen conjugates for breast cancer therapy.
Bioconjug Chem
; 24(9): 1468-84, 2013 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23909664
7.
Photoswitchable Molecular Glues Enable Optical Control of Transcription Factor Degradation.
bioRxiv
; 2023 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37066279
8.
A molecular glue approach to control the half-life of CRISPR-based technologies.
bioRxiv
; 2023 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945568
9.
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
bioRxiv
; 2023 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865221
10.
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
Cell Metab
; 35(5): 887-905.e11, 2023 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37075753
11.
CRISPR-based therapeutics: current challenges and future applications.
Trends Pharmacol Sci
; 43(2): 151-161, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34952739
12.
A general approach to identify cell-permeable and synthetic anti-CRISPR small molecules.
Nat Cell Biol
; 24(12): 1766-1775, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36396978
13.
Self-assembled supramolecular nanomicelles from a bile acid-docetaxel conjugate are highly tolerable with improved therapeutic efficacy.
Biomater Sci
; 9(16): 5626-5639, 2021 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34254078
14.
Engineering designer beta cells with a CRISPR-Cas9 conjugation platform.
Nat Commun
; 11(1): 4043, 2020 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32792475
15.
Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes.
ACS Cent Sci
; 6(12): 2228-2237, 2020 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33376784
16.
A 3D culture platform enables development of zinc-binding prodrugs for targeted proliferation of ß cells.
Sci Adv
; 6(47)2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33208361
17.
Recent Advances in Engineering of Lipid Drug Conjugates for Cancer Therapy.
ACS Biomater Sci Eng
; 5(9): 4148-4166, 2019 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33417775
18.
Design, synthesis, and physico-chemical interactions of bile acid derived dimeric phospholipid amphiphiles with model membranes.
J Colloid Interface Sci
; 448: 398-406, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25746193
19.
Synthesis, Structure-Activity Relationship, and Mechanistic Investigation of Lithocholic Acid Amphiphiles for Colon Cancer Therapy.
Medchemcomm
; 6(1): 192-201, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25685308
20.
Nature of the charged headgroup determines the fusogenic potential and membrane properties of lithocholic acid phospholipids.
J Phys Chem B
; 118(31): 9341-8, 2014 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25029367