Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis.

Skau, Colleen T; Fischer, Robert S; Gurel, Pinar; Thiam, Hawa Racine; Tubbs, Anthony; Baird, Michelle A; Davidson, Michael W; Piel, Matthieu; Alushin, Gregory M; Nussenzweig, Andre; Steeg, Patricia S; Waterman, Clare M.

Cell ; 167(6): 1571-1585.e18, 2016 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-27839864

2.

Retraction Notice to: FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis.

Skau, Colleen T; Fischer, Robert S; Gurel, Pinar; Thiam, Hawa Racine; Tubbs, Anthony; Baird, Michelle A; Davidson, Michael W; Piel, Matthieu; Alushin, Gregory M; Nussenzweig, Andre; Steeg, Patricia S; Waterman, Clare M.

Cell ; 173(2): 529, 2018 04 05.

Artigo em Inglês | MEDLINE | ID: mdl-29625058

3.

A perspective on the metastasis suppressor field.

Khan, Imran; Steeg, Patricia S.

Cancer Metastasis Rev ; 42(4): 1061-1063, 2023 12.

Artigo em Inglês | MEDLINE | ID: mdl-37581870

4.

National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities.

Kim, Michelle M; Mehta, Minesh P; Smart, DeeDee K; Steeg, Patricia S; Hong, Julie A; Espey, Michael G; Prasanna, Pataje G; Crandon, Laura; Hodgdon, Christine; Kozak, Niki; Armstrong, Terri S; Morikawa, Aki; Willmarth, Nicole; Tanner, Kirk; Boire, Adrienne; Gephart, Melanie Hayden; Margolin, Kim A; Hattangadi-Gluth, Jona; Tawbi, Hussein; Trifiletti, Daniel M; Chung, Caroline; Basu-Roy, Upal; Burns, Robyn; Oliva, Isabella C Glitza; Aizer, Ayal A; Anders, Carey K; Davis, Joanne; Ahluwalia, Manmeet S; Chiang, Veronica; Li, Jing; Kotecha, Rupesh; Formenti, Silvia C; Ellingson, Benjamin M; Gondi, Vinai; Sperduto, Paul W; Barnholtz-Sloan, Jill S; Rodon, Jordi; Lee, Eudocia Q; Khasraw, Mustafa; Yeboa, Debra Nana; Brastianos, Priscilla K; Galanis, Evanthia; Coleman, C Norman; Ahmed, Mansoor M.

Lancet Oncol ; 24(8): e344-e354, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37541280

5.

Endocytosis: a pivotal pathway for regulating metastasis.

Khan, Imran; Steeg, Patricia S.

Br J Cancer ; 124(1): 66-75, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33262521

6.

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.

Zhang, Lin; Zhang, Siyuan; Yao, Jun; Lowery, Frank J; Zhang, Qingling; Huang, Wen-Chien; Li, Ping; Li, Min; Wang, Xiao; Zhang, Chenyu; Wang, Hai; Ellis, Kenneth; Cheerathodi, Mujeeburahiman; McCarty, Joseph H; Palmieri, Diane; Saunus, Jodi; Lakhani, Sunil; Huang, Suyun; Sahin, Aysegul A; Aldape, Kenneth D; Steeg, Patricia S; Yu, Dihua.

Nature ; 527(7576): 100-104, 2015 Nov 05.

Artigo em Inglês | MEDLINE | ID: mdl-26479035

7.

Antibody-drug conjugates for cancer.

Chau, Cindy H; Steeg, Patricia S; Figg, William D.

Lancet ; 394(10200): 793-804, 2019 08 31.

Artigo em Inglês | MEDLINE | ID: mdl-31478503

8.

Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.

Zimmer, Alexandra S; Steinberg, Seth M; Smart, Dee Dee; Gilbert, Mark R; Armstrong, Terri S; Burton, Eric; Houston, Nicole; Biassou, Nadia; Gril, Brunilde; Brastianos, Priscilla K; Carter, Scott; Lyden, David; Lipkowitz, Stanley; Steeg, Patricia S.

Future Oncol ; 16(14): 899-909, 2020 May.

Artigo em Inglês | MEDLINE | ID: mdl-32270710

9.

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer.

Greer, Yoshimi Endo; Gilbert, Samuel F; Gril, Brunilde; Narwal, Rajesh; Peacock Brooks, Danielle L; Tice, David A; Steeg, Patricia S; Lipkowitz, Stanley.

Breast Cancer Res ; 21(1): 27, 2019 02 18.

Artigo em Inglês | MEDLINE | ID: mdl-30777098

10.

Metastasis suppressors: functional pathways.

Khan, Imran; Steeg, Patricia S.

Lab Invest ; 98(2): 198-210, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-28967874

11.

Analysis of breast cancer in young women in the Department of Defense (DOD) database.

Zimmer, Alexandra S; Zhu, Kangmin; Steeg, Patricia S; Wu, Alex; Gatti-Mays, Margaret E; Soltani, Sanaz; Perkins, Jeremy G; Shao, Stephanie; Brown, Derek; Georg, Matthew; Hu, Hai; Shriver, Craig D; Lipkowitz, Stanley.

Breast Cancer Res Treat ; 168(2): 501-511, 2018 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-29247440

12.

Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer.

Samala, Ramakrishna; Thorsheim, Helen R; Goda, Satyanarayana; Taskar, Kunal; Gril, Brunilde; Steeg, Patricia S; Smith, Quentin R.

Pharm Res ; 33(12): 2904-2919, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27541873

13.

Predicting early brain metastases based on clinicopathological factors and gene expression analysis in advanced HER2-positive breast cancer patients.

Duchnowska, Renata; Jassem, Jacek; Goswami, Chirayu Pankaj; Dundar, Murat; Gökmen-Polar, Yesim; Li, Lang; Woditschka, Stephan; Biernat, Wojciech; Sosinska-Mielcarek, Katarzyna; Czartoryska-Arlukowicz, Bogumila; Radecka, Barbara; Tomasevic, Zorica; Stepniak, Piotr; Wojdan, Konrad; Sledge, George W; Steeg, Patricia S; Badve, Sunil.

J Neurooncol ; 122(1): 205-16, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25559688

14.

A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.

McMullin, Ryan P; Wittner, Ben S; Yang, Chuanwei; Denton-Schneider, Benjamin R; Hicks, Daniel; Singavarapu, Raj; Moulis, Sharon; Lee, Jeongeun; Akbari, Mohammad R; Narod, Steven A; Aldape, Kenneth D; Steeg, Patricia S; Ramaswamy, Sridhar; Sgroi, Dennis C.

Breast Cancer Res ; 16(2): R25, 2014 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-24625110

15.

A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007.

Miller, Kathy D; Althouse, Sandra K; Nabell, Lisle; Rugo, Hope; Carey, Lisa; Kimmick, Gretchen; Jones, David R; Merino, Maria J; Steeg, Patricia S.

Breast Cancer Res Treat ; 148(1): 99-106, 2014 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-25257727

16.

Breast cancer metastasis: issues for the personalization of its prevention and treatment.

Marino, Natascia; Woditschka, Stephan; Reed, L Tiffany; Nakayama, Joji; Mayer, Musa; Wetzel, Maria; Steeg, Patricia S.

Am J Pathol ; 183(4): 1084-1095, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23895915

17.

Pazopanib inhibits the activation of PDGFRß-expressing astrocytes in the brain metastatic microenvironment of breast cancer cells.

Gril, Brunilde; Palmieri, Diane; Qian, Yongzhen; Anwar, Talha; Liewehr, David J; Steinberg, Seth M; Andreu, Zoraida; Masana, Daniel; Fernández, Paloma; Steeg, Patricia S; Vidal-Vanaclocha, Fernando.

Am J Pathol ; 182(6): 2368-79, 2013 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-23583652

18.

Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+ brain metastases of breast cancer.

Silvestri, Vanesa L; Tran, Andy D; Chung, Monika; Chung, Natalie; Gril, Brunilde; Robinson, Christina; Difilippantonio, Simone; Wei, Debbie; Kruhlak, Michael J; Peer, Cody J; Figg, W Douglas; Khan, Imran; Steeg, Patricia S.

Neuro Oncol ; 26(6): 1067-1082, 2024 Jun 03.

Artigo em Inglês | MEDLINE | ID: mdl-38363979

19.

Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene.

Marino, Natascia; Nakayama, Joji; Collins, Joshua W; Steeg, Patricia S.

Cancer Metastasis Rev ; 31(3-4): 593-603, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22706779

20.

Metastasis gets site specific.

Horak, Christine E; Steeg, Patricia S.

Cancer Cell ; 8(2): 93-5, 2005 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-16098461

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FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis.

Retraction Notice to: FMN2 Makes Perinuclear Actin to Protect Nuclei during Confined Migration and Promote Metastasis.

A perspective on the metastasis suppressor field.

National Cancer Institute Collaborative Workshop on Shaping the Landscape of Brain Metastases Research: challenges and recommended priorities.

Endocytosis: a pivotal pathway for regulating metastasis.

Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.

Antibody-drug conjugates for cancer.

Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer.

Metastasis suppressors: functional pathways.

Analysis of breast cancer in young women in the Department of Defense (DOD) database.

Vinorelbine Delivery and Efficacy in the MDA-MB-231BR Preclinical Model of Brain Metastases of Breast Cancer.

Predicting early brain metastases based on clinicopathological factors and gene expression analysis in advanced HER2-positive breast cancer patients.

A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.

A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007.

Breast cancer metastasis: issues for the personalization of its prevention and treatment.

Pazopanib inhibits the activation of PDGFRß-expressing astrocytes in the brain metastatic microenvironment of breast cancer cells.

Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+ brain metastases of breast cancer.

Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene.

Metastasis gets site specific.