Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention.

Stephenson, Kathryn E; Wagh, Kshitij; Korber, Bette; Barouch, Dan H.

Annu Rev Immunol ; 38: 673-703, 2020 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-32340576

2.

Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys.

Barouch, Dan H; Stephenson, Kathryn E; Borducchi, Erica N; Smith, Kaitlin; Stanley, Kelly; McNally, Anna G; Liu, Jinyan; Abbink, Peter; Maxfield, Lori F; Seaman, Michael S; Dugast, Anne-Sophie; Alter, Galit; Ferguson, Melissa; Li, Wenjun; Earl, Patricia L; Moss, Bernard; Giorgi, Elena E; Szinger, James J; Eller, Leigh Anne; Billings, Erik A; Rao, Mangala; Tovanabutra, Sodsai; Sanders-Buell, Eric; Weijtens, Mo; Pau, Maria G; Schuitemaker, Hanneke; Robb, Merlin L; Kim, Jerome H; Korber, Bette T; Michael, Nelson L.

Cell ; 155(3): 531-9, 2013 Oct 24.

Artigo em Inglês | MEDLINE | ID: mdl-24243013

3.

Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans.

Alter, Galit; Yu, Jingyou; Liu, Jinyan; Chandrashekar, Abishek; Borducchi, Erica N; Tostanoski, Lisa H; McMahan, Katherine; Jacob-Dolan, Catherine; Martinez, David R; Chang, Aiquan; Anioke, Tochi; Lifton, Michelle; Nkolola, Joseph; Stephenson, Kathryn E; Atyeo, Caroline; Shin, Sally; Fields, Paul; Kaplan, Ian; Robins, Harlan; Amanat, Fatima; Krammer, Florian; Baric, Ralph S; Le Gars, Mathieu; Sadoff, Jerald; de Groot, Anne Marit; Heerwegh, Dirk; Struyf, Frank; Douoguih, Macaya; van Hoof, Johan; Schuitemaker, Hanneke; Barouch, Dan H.

Nature ; 596(7871): 268-272, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34107529

4.

Modeling resistance to the broadly neutralizing antibody PGT121 in people living with HIV-1.

Cassidy, Tyler; Stephenson, Kathryn E; Barouch, Dan H; Perelson, Alan S.

PLoS Comput Biol ; 20(3): e1011518, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38551976

5.

Interim Results of a Phase 1-2a Trial of Ad26.COV2.S Covid-19 Vaccine.

Sadoff, Jerald; Le Gars, Mathieu; Shukarev, Georgi; Heerwegh, Dirk; Truyers, Carla; de Groot, Anne M; Stoop, Jeroen; Tete, Sarah; Van Damme, Wim; Leroux-Roels, Isabel; Berghmans, Pieter-Jan; Kimmel, Murray; Van Damme, Pierre; de Hoon, Jan; Smith, William; Stephenson, Kathryn E; De Rosa, Stephen C; Cohen, Kristen W; McElrath, M Juliana; Cormier, Emmanuel; Scheper, Gert; Barouch, Dan H; Hendriks, Jenny; Struyf, Frank; Douoguih, Macaya; Van Hoof, Johan; Schuitemaker, Hanneke.

N Engl J Med ; 384(19): 1824-1835, 2021 05 13.

Artigo em Inglês | MEDLINE | ID: mdl-33440088

6.

Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study.

Stieh, Daniel J; Barouch, Dan H; Comeaux, Christy; Sarnecki, Michal; Stephenson, Kathryn E; Walsh, Stephen R; Sawant, Sheetal; Heptinstall, Jack; Tomaras, Georgia D; Kublin, James G; McElrath, M Juliana; Cohen, Kristen W; De Rosa, Stephen C; Alter, Galit; Ferrari, Guido; Montefiori, David; Mann, Philipp; Nijs, Steven; Callewaert, Katleen; Goepfert, Paul A; Edupuganti, Srilatha; Karita, Etienne; Seaman, Michael S; Corey, Lawrence; Baden, Lindsey R; Pau, Maria G; Schuitemaker, Hanneke; Tomaka, Frank.

J Infect Dis ; 227(8): 939-950, 2023 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-36348617

7.

Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys.

Borducchi, Erica N; Cabral, Crystal; Stephenson, Kathryn E; Liu, Jinyan; Abbink, Peter; Ng'ang'a, David; Nkolola, Joseph P; Brinkman, Amanda L; Peter, Lauren; Lee, Benjamin C; Jimenez, Jessica; Jetton, David; Mondesir, Jade; Mojta, Shanell; Chandrashekar, Abishek; Molloy, Katherine; Alter, Galit; Gerold, Jeffrey M; Hill, Alison L; Lewis, Mark G; Pau, Maria G; Schuitemaker, Hanneke; Hesselgesser, Joseph; Geleziunas, Romas; Kim, Jerome H; Robb, Merlin L; Michael, Nelson L; Barouch, Dan H.

Nature ; 540(7632): 284-287, 2016 12 08.

Artigo em Inglês | MEDLINE | ID: mdl-27841870

8.

A Double-Blind, Randomized, Placebo-Controlled Phase 1 Study of Ad26.ZIKV.001, an Ad26-Vectored Anti-Zika Virus Vaccine.

Salisch, Nadine C; Stephenson, Kathryn E; Williams, Kristi; Cox, Freek; van der Fits, Leslie; Heerwegh, Dirk; Truyers, Carla; Habets, Marrit N; Kanjilal, Diane G; Larocca, Rafael A; Abbink, Peter; Liu, Jinyan; Peter, Lauren; Fierro, Carlos; De La Barrera, Rafael A; Modjarrad, Kayvon; Zahn, Roland C; Hendriks, Jenny; Cahill, Conor P; Leyssen, Maarten; Douoguih, Macaya; van Hoof, Johan; Schuitemaker, Hanneke; Barouch, Dan H.

Ann Intern Med ; 174(5): 585-594, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33587687

9.

Compassionate Use of Remdesivir in Pregnant Women With Severe Coronavirus Disease 2019.

Burwick, Richard M; Yawetz, Sigal; Stephenson, Kathryn E; Collier, Ai-Ris Y; Sen, Pritha; Blackburn, Brian G; Kojic, E Milunka; Hirshberg, Adi; Suarez, Jose F; Sobieszczyk, Magdalena E; Marks, Kristen M; Mazur, Shawn; Big, Cecilia; Manuel, Oriol; Morlin, Gregory; Rose, Suzanne J; Naqvi, Mariam; Goldfarb, Ilona T; DeZure, Adam; Telep, Laura; Tan, Susanna K; Zhao, Yang; Hahambis, Tom; Hindman, Jason; Chokkalingam, Anand P; Carter, Christoph; Das, Moupali; Osinusi, Anu O; Brainard, Diana M; Varughese, Tilly A; Kovalenko, Olga; Sims, Matthew D; Desai, Samit; Swamy, Geeta; Sheffield, Jeanne S; Zash, Rebecca; Short, William R.

Clin Infect Dis ; 73(11): e3996-e4004, 2021 12 06.

Artigo em Inglês | MEDLINE | ID: mdl-33031500

10.

Immunogenicity of the Ad26.COV2.S Vaccine for COVID-19.

Stephenson, Kathryn E; Le Gars, Mathieu; Sadoff, Jerald; de Groot, Anne Marit; Heerwegh, Dirk; Truyers, Carla; Atyeo, Caroline; Loos, Carolin; Chandrashekar, Abishek; McMahan, Katherine; Tostanoski, Lisa H; Yu, Jingyou; Gebre, Makda S; Jacob-Dolan, Catherine; Li, Zhenfeng; Patel, Shivani; Peter, Lauren; Liu, Jinyan; Borducchi, Erica N; Nkolola, Joseph P; Souza, Morgana; Tan, Chen Sabrina; Zash, Rebecca; Julg, Boris; Nathavitharana, Ruvandhi R; Shapiro, Roger L; Azim, Ahmed Abdul; Alonso, Carolyn D; Jaegle, Kate; Ansel, Jessica L; Kanjilal, Diane G; Guiney, Caitlin J; Bradshaw, Connor; Tyler, Anna; Makoni, Tatenda; Yanosick, Katherine E; Seaman, Michael S; Lauffenburger, Douglas A; Alter, Galit; Struyf, Frank; Douoguih, Macaya; Van Hoof, Johan; Schuitemaker, Hanneke; Barouch, Dan H.

JAMA ; 325(15): 1535-1544, 2021 04 20.

Artigo em Inglês | MEDLINE | ID: mdl-33704352

11.

Live-attenuated Chikungunya vaccine: a possible new era.

Stephenson, Kathryn E.

Lancet ; 401(10394): 2090-2091, 2023 06 24.

Artigo em Inglês | MEDLINE | ID: mdl-37321234

12.

Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials.

Modjarrad, Kayvon; Lin, Leyi; George, Sarah L; Stephenson, Kathryn E; Eckels, Kenneth H; De La Barrera, Rafael A; Jarman, Richard G; Sondergaard, Erica; Tennant, Janice; Ansel, Jessica L; Mills, Kristin; Koren, Michael; Robb, Merlin L; Barrett, Jill; Thompson, Jason; Kosel, Alison E; Dawson, Peter; Hale, Andrew; Tan, C Sabrina; Walsh, Stephen R; Meyer, Keith E; Brien, James; Crowell, Trevor A; Blazevic, Azra; Mosby, Karla; Larocca, Rafael A; Abbink, Peter; Boyd, Michael; Bricault, Christine A; Seaman, Michael S; Basil, Anne; Walsh, Melissa; Tonwe, Veronica; Hoft, Daniel F; Thomas, Stephen J; Barouch, Dan H; Michael, Nelson L.

Lancet ; 391(10120): 563-571, 2018 02 10.

Artigo em Inglês | MEDLINE | ID: mdl-29217375

13.

Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19).

Barouch, Dan H; Tomaka, Frank L; Wegmann, Frank; Stieh, Daniel J; Alter, Galit; Robb, Merlin L; Michael, Nelson L; Peter, Lauren; Nkolola, Joseph P; Borducchi, Erica N; Chandrashekar, Abishek; Jetton, David; Stephenson, Kathryn E; Li, Wenjun; Korber, Bette; Tomaras, Georgia D; Montefiori, David C; Gray, Glenda; Frahm, Nicole; McElrath, M Juliana; Baden, Lindsey; Johnson, Jennifer; Hutter, Julia; Swann, Edith; Karita, Etienne; Kibuuka, Hannah; Mpendo, Juliet; Garrett, Nigel; Mngadi, Kathy; Chinyenze, Kundai; Priddy, Frances; Lazarus, Erica; Laher, Fatima; Nitayapan, Sorachai; Pitisuttithum, Punnee; Bart, Stephan; Campbell, Thomas; Feldman, Robert; Lucksinger, Gregg; Borremans, Caroline; Callewaert, Katleen; Roten, Raphaele; Sadoff, Jerald; Scheppler, Lorenz; Weijtens, Mo; Feddes-de Boer, Karin; van Manen, Daniëlle; Vreugdenhil, Jessica; Zahn, Roland; Lavreys, Ludo.

Lancet ; 392(10143): 232-243, 2018 07 21.

Artigo em Inglês | MEDLINE | ID: mdl-30047376

14.

Durable Humoral and Cellular Immune Responses 8 Months after Ad26.COV2.S Vaccination.

Barouch, Dan H; Stephenson, Kathryn E; Sadoff, Jerald; Yu, Jingyou; Chang, Aiquan; Gebre, Makda; McMahan, Katherine; Liu, Jinyan; Chandrashekar, Abishek; Patel, Shivani; Le Gars, Mathieu; de Groot, Anne M; Heerwegh, Dirk; Struyf, Frank; Douoguih, Macaya; van Hoof, Johan; Schuitemaker, Hanneke.

N Engl J Med ; 385(10): 951-953, 2021 09 02.

Artigo em Inglês | MEDLINE | ID: mdl-34260834

15.

Similar Epitope Specificities of IgG and IgA Antibodies Elicited by Ad26 Vector Prime, Env Protein Boost Immunizations in Rhesus Monkeys.

Kang, Zi Han; Bricault, Christine A; Borducchi, Erica N; Stephenson, Kathryn E; Seaman, Michael S; Pau, Maria; Schuitemaker, Hanneke; van Manen, Danielle; Wegmann, Frank; Barouch, Dan H.

J Virol ; 92(15)2018 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-29793950

16.

Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs.

Bricault, Christine A; Kovacs, James M; Badamchi-Zadeh, Alexander; McKee, Krisha; Shields, Jennifer L; Gunn, Bronwyn M; Neubauer, George H; Ghantous, Fadi; Jennings, Julia; Gillis, Lindsey; Perry, James; Nkolola, Joseph P; Alter, Galit; Chen, Bing; Stephenson, Kathryn E; Doria-Rose, Nicole; Mascola, John R; Seaman, Michael S; Barouch, Dan H.

J Virol ; 92(13)2018 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-29643249

17.

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys.

Barouch, Dan H; Whitney, James B; Moldt, Brian; Klein, Florian; Oliveira, Thiago Y; Liu, Jinyan; Stephenson, Kathryn E; Chang, Hui-Wen; Shekhar, Karthik; Gupta, Sanjana; Nkolola, Joseph P; Seaman, Michael S; Smith, Kaitlin M; Borducchi, Erica N; Cabral, Crystal; Smith, Jeffrey Y; Blackmore, Stephen; Sanisetty, Srisowmya; Perry, James R; Beck, Matthew; Lewis, Mark G; Rinaldi, William; Chakraborty, Arup K; Poignard, Pascal; Nussenzweig, Michel C; Burton, Dennis R.

Nature ; 503(7475): 224-8, 2013 Nov 14.

Artigo em Inglês | MEDLINE | ID: mdl-24172905

18.

First-in-Human Randomized, Controlled Trial of Mosaic HIV-1 Immunogens Delivered via a Modified Vaccinia Ankara Vector.

Baden, Lindsey R; Walsh, Stephen R; Seaman, Michael S; Cohen, Yehuda Z; Johnson, Jennifer A; Licona, J Humberto; Filter, Rachel D; Kleinjan, Jane A; Gothing, Jon A; Jennings, Julia; Peter, Lauren; Nkolola, Joseph; Abbink, Peter; Borducchi, Erica N; Kirilova, Marinela; Stephenson, Kathryn E; Pegu, Poonam; Eller, Michael A; Trinh, Hung V; Rao, Mangala; Ake, Julie A; Sarnecki, Michal; Nijs, Steven; Callewaert, Katleen; Schuitemaker, Hanneke; Hendriks, Jenny; Pau, Maria G; Tomaka, Frank; Korber, Bette T; Alter, Galit; Dolin, Raphael; Earl, Patricia L; Moss, Bernard; Michael, Nelson L; Robb, Merlin L; Barouch, Dan H.

J Infect Dis ; 218(4): 633-644, 2018 07 13.

Artigo em Inglês | MEDLINE | ID: mdl-29669026

19.

A global approach to HIV-1 vaccine development.

Stephenson, Kathryn E; Barouch, Dan H.

Immunol Rev ; 254(1): 295-304, 2013 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-23772627

20.

Broadly Neutralizing Antibodies for HIV Eradication.