Detalhe da pesquisa
1.
Physiologically based kinetic (PBK) modeling as a new approach methodology (NAM) for predicting systemic levels of gut microbial metabolites.
Toxicol Lett
; 396: 94-102, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38685289
2.
Physiologically-Based Pharmacokinetic Modeling of the Postbiotic Supplement Urolithin A Predicts its Bioavailability Is Orders of Magnitude Lower than Concentrations that Induce Toxicity, but also Neuroprotective Effects.
Mol Nutr Food Res
; 67(15): e2300009, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37195009
3.
Breaking through the barrier: Modelling and exploiting the physical microenvironment to enhance drug transport and efficacy.
Adv Drug Deliv Rev
; 184: 114183, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35278523