Detalhe da pesquisa
1.
Onset of hippocampal network aberration and memory deficits in P301S tau mice are associated with an early gene signature.
Brain
; 143(6): 1889-1904, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375177
2.
Role of EphA4 in Mediating Motor Neuron Death in MND.
Int J Mol Sci
; 22(17)2021 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34502339
3.
Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies.
Brain
; 141(2): 521-534, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29253099
4.
Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice.
J Neurochem
; 132(1): 135-45, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25041093
5.
Early-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degeneration.
Neuropathol Appl Neurobiol
; 41(7): 906-25, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25763777
6.
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Acta Neuropathol
; 130(5): 661-78, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26437864
7.
Increased Neuronal Nitric Oxide Synthase in Alzheimer's Disease Mediates Spontaneous Calcium Signaling and Divergent Glutamatergic Calcium Responses.
Antioxid Redox Signal
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38299492
8.
Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Neuron
; 112(8): 1249-1264.e8, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38366598
9.
Glia: initiators and progressors of pathology in Parkinson's disease.
Mov Disord
; 26(1): 6-17, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21322014
10.
Unbiased Label-Free Quantitative Proteomics of Cells Expressing Amyotrophic Lateral Sclerosis (ALS) Mutations in CCNF Reveals Activation of the Apoptosis Pathway: A Workflow to Screen Pathogenic Gene Mutations.
Front Mol Neurosci
; 14: 627740, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33986643
11.
The mRNA-based reprogramming of fibroblasts from a SOD1E101G familial amyotrophic lateral sclerosis patient to induced pluripotent stem cell line UOWi007.
Stem Cell Res
; 42: 101701, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32006803
12.
Increased Tau Phosphorylation in Motor Neurons From Clinically Pure Sporadic Amyotrophic Lateral Sclerosis Patients.
J Neuropathol Exp Neurol
; 78(7): 605-614, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31131395
13.
Generation and characterization of a human induced pluripotent stem cell line UOWi005-A from dermal fibroblasts derived from a CCNFS621G familial amyotrophic lateral sclerosis patient using mRNA reprogramming.
Stem Cell Res
; 40: 101530, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31445393
14.
The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation.
Cells
; 8(6)2019 06 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31200561
15.
Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1.
Stem Cell Res
; 31: 227-230, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30138848
16.
The Polyphenol Altenusin Inhibits in Vitro Fibrillization of Tau and Reduces Induced Tau Pathology in Primary Neurons.
ACS Chem Neurosci
; 8(4): 743-751, 2017 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28067492
17.
Disinhibition-like behavior in a P301S mutant tau transgenic mouse model of frontotemporal dementia.
Neurosci Lett
; 631: 24-29, 2016 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27521751
18.
Site-specific phosphorylation of tau inhibits amyloid-ß toxicity in Alzheimer's mice.
Science
; 354(6314): 904-908, 2016 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856911
19.
Aß-dependent reduction of NCAM2-mediated synaptic adhesion contributes to synapse loss in Alzheimer's disease.
Nat Commun
; 6: 8836, 2015 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26611261
20.
α-Synucleinopathy phenotypes.
Parkinsonism Relat Disord
; 20 Suppl 1: S62-7, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24262191