Detalhe da pesquisa
1.
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain.
Development
; 149(23)2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36305490
2.
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease.
Brain
; 145(9): 3035-3057, 2022 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34936701
3.
A TRPV1-to-secretagogin regulatory axis controls pancreatic ß-cell survival by modulating protein turnover.
EMBO J
; 36(14): 2107-2125, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28637794
4.
C4b-binding Protein Protects ß-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity.
J Biol Chem
; 291(41): 21644-21655, 2016 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27566545
5.
Palmitoylation of Ca2+ channel subunit CaVß2a induces pancreatic beta-cell toxicity via Ca2+ overload.
Biochem Biophys Res Commun
; 491(3): 740-746, 2017 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739256
6.
Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.
Proc Natl Acad Sci U S A
; 111(38): 13924-9, 2014 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25201977
7.
Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.
Hum Mol Genet
; 23(21): 5733-49, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24916378
8.
Low birthweight is associated with an increased risk of LADA and type 2 diabetes: results from a Swedish case-control study.
Diabetologia
; 58(11): 2525-32, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26208603
9.
Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.
Biochem Biophys Res Commun
; 460(3): 518-24, 2015 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25797618
10.
Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells).
Gut
; 63(1): 131-42, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23348960
11.
Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death.
J Biol Chem
; 288(24): 17460-71, 2013 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23629662
12.
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo.
Mol Ther Methods Clin Dev
; 29: 381-394, 2023 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37251982
13.
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD.
Cell Stem Cell
; 30(10): 1299-1314.e9, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37802036
14.
Pathogen specific, IRF3-dependent signaling and innate resistance to human kidney infection.
PLoS Pathog
; 6(9): e1001109, 2010 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20886096
15.
HAMLET: functional properties and therapeutic potential.
Future Oncol
; 8(10): 1301-13, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23130929
16.
Silk scaffolding drives self-assembly of functional and mature human brain organoids.
Front Cell Dev Biol
; 10: 1023279, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36313550
17.
Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson's disease.
Stem Cell Reports
; 17(10): 2203-2219, 2022 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36150382
18.
Islet Gene View-a tool to facilitate islet research.
Life Sci Alliance
; 5(12)2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948367
19.
Dopamine Neuron Diversity: Recent Advances and Current Challenges in Human Stem Cell Models and Single Cell Sequencing.
Cells
; 10(6)2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34206038
20.
Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation.
Cells
; 10(1)2021 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33445654