Detalhe da pesquisa
1.
Tepotinib in Non-Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations.
N Engl J Med
; 383(10): 931-943, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32469185
2.
IgG1 anti-epidermal growth factor receptor antibodies induce CD8-dependent antitumor activity.
Int J Cancer
; 136(4): 821-30, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947844
3.
Activity of Tepotinib in Hepatocellular Carcinoma With High-Level MET Amplification: Preclinical and Clinical Evidence.
JCO Precis Oncol
; 8: e2300328, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38354329
4.
The Preclinical Pharmacology of Tepotinib-A Highly Selective MET Inhibitor with Activity in Tumors Harboring MET Alterations.
Mol Cancer Ther
; 22(7): 833-843, 2023 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36999986
5.
Immunological and tumor-intrinsic mechanisms mediate the synergistic growth suppression of experimental glioblastoma by radiotherapy and MET inhibition.
Acta Neuropathol Commun
; 11(1): 41, 2023 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36915128
6.
Tepotinib in patients with non-small cell lung cancer with high-level MET amplification detected by liquid biopsy: VISION Cohort B.
Cell Rep Med
; 4(11): 101280, 2023 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37944528
7.
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer.
N Engl J Med
; 360(14): 1408-17, 2009 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19339720
8.
Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study.
Lancet Oncol
; 12(8): 795-805, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21782507
9.
Brain penetration and efficacy of tepotinib in orthotopic patient-derived xenograft models of MET-driven non-small cell lung cancer brain metastases.
Lung Cancer
; 163: 77-86, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34942492
10.
Translational pharmacokinetic-pharmacodynamic modeling of preclinical and clinical data of the oral MET inhibitor tepotinib to determine the recommended phase II dose.
CPT Pharmacometrics Syst Pharmacol
; 10(5): 428-440, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33818908
11.
Real-world insights into patients with advanced NSCLC and MET alterations.
Lung Cancer
; 159: 96-106, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320421
12.
Landscape and Clonal Dominance of Co-occurring Genomic Alterations in Non-Small-Cell Lung Cancer Harboring MET Exon 14 Skipping.
JCO Precis Oncol
; 52021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34957368
13.
The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping.
Cancer Treat Rev
; 87: 102022, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32334240
14.
Cetuximab-Mediated Protection from Hypoxia- Induced Cell Death: Implications for Therapy Sequence in Colorectal Cancer.
Cancers (Basel)
; 12(10)2020 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33092032
15.
SHP2 Inhibition Influences Therapeutic Response to Tepotinib in Tumors with MET Alterations.
iScience
; 23(12): 101832, 2020 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33305187
16.
Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma.
Mol Cancer Ther
; 19(2): 614-626, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31744898
17.
Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.
Mol Biol Cell
; 13(3): 978-88, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11907276
18.
The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer.
Clin Cancer Res
; 22(13): 3260-7, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26888827
19.
Specific inhibition of transcription factor NF-kappaB through intracellular protein delivery of I kappaBalpha by the Herpes virus protein VP22.
Oncogene
; 22(34): 5367-73, 2003 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12917639
20.
Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B.
J Invest Dermatol
; 124(1): 38-45, 2005 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-15654951