Detalhe da pesquisa
1.
Correction of a urea cycle defect after ex vivo gene editing of human hepatocytes.
Mol Ther
; 29(5): 1903-1917, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33484963
2.
Effects of Pro-Inflammatory Cytokines on Hepatic Metabolism in Primary Human Hepatocytes.
Int J Mol Sci
; 23(23)2022 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36499207
3.
Insights From Liver-Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR-Agonist Pharmacodynamics in Humans.
Hepatology
; 72(2): 656-670, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31785104
4.
Ectonucleotidase Expression on Human Amnion Epithelial Cells: Adenosinergic Pathways and Dichotomic Effects on Immune Effector Cell Populations.
J Immunol
; 202(3): 724-735, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30587530
5.
Gene Editing Correction of a Urea Cycle Defect in Organoid Stem Cell Derived Hepatocyte-like Cells.
Int J Mol Sci
; 22(3)2021 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33530582
6.
From pain to gain: Leveraging acetaminophen in hepatocyte transplantation for phenylketonuria.
Hepatology
; 79(5): 973-975, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38085850
7.
Targeting HSP90 with the small molecule inhibitor AUY922 (luminespib) as a treatment strategy against hepatocellular carcinoma.
Int J Cancer
; 144(10): 2613-2624, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30488605
8.
Evaluation of different routes of administration and biodistribution of human amnion epithelial cells in mice.
Cytotherapy
; 21(1): 113-124, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30409699
9.
A liver-humanized mouse model of carbamoyl phosphate synthetase 1-deficiency.
J Inherit Metab Dis
; 42(6): 1054-1063, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30843237
10.
Host conditioning and rejection monitoring in hepatocyte transplantation in humans.
J Hepatol
; 66(5): 987-1000, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28027971
11.
Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiency.
Hepatology
; 62(1): 147-57, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25690322
12.
Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny.
Drug Metab Dispos
; 44(7): 1027-37, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26921389
13.
Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase.
J Biol Chem
; 289(30): 20583-93, 2014 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895126
14.
Clinical hepatocyte transplantation: practical limits and possible solutions.
Eur Surg Res
; 54(3-4): 162-77, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25633583
15.
Placental stem cell correction of murine intermediate maple syrup urine disease.
Hepatology
; 57(3): 1017-23, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23175463
16.
Why do most human liver cytosol preparations lack xanthine oxidase activity?
Drug Metab Dispos
; 42(4): 695-9, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24430612
17.
Frequent aneuploidy among normal human hepatocytes.
Gastroenterology
; 142(1): 25-8, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22057114
18.
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver.
Genome Res
; 20(8): 1020-36, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20538623
19.
Improved amino acid, bioenergetic metabolite and neurotransmitter profiles following human amnion epithelial cell transplant in intermediate maple syrup urine disease mice.
Mol Genet Metab
; 109(2): 132-8, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23566440
20.
Ritonavir and efavirenz significantly alter the metabolism of erlotinib--an observation in primary cultures of human hepatocytes that is relevant to HIV patients with cancer.
Drug Metab Dispos
; 41(10): 1843-51, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23913028