Detalhe da pesquisa
1.
Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.
Bioorg Med Chem Lett
; 21(14): 4228-32, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21684157
2.
Inhibition of inducible nitric oxide synthase in respiratory diseases.
Biochem Soc Trans
; 37(Pt 4): 886-91, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19614613
3.
BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.
Mol Pharmacol
; 73(4): 1244-53, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18178668
4.
The putative helical lid of the Hsp70 peptide-binding domain is required for efficient preprotein translocation into mitochondria.
J Mol Biol
; 334(5): 1087-99, 2003 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-14643668
5.
Impaired interdomain communication in mitochondrial Hsp70 results in the loss of inward-directed translocation force.
J Biol Chem
; 284(5): 2934-2946, 2009 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19036727
6.
Montelukast exerts no acute direct effect on NO synthases.
Pulm Pharmacol Ther
; 20(5): 525-33, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-16815057
7.
The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.
Mol Pharmacol
; 69(1): 328-37, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16223957
8.
Mitochondrial protein sorting: differentiation of beta-barrel assembly by Tom7-mediated segregation of Mdm10.
J Biol Chem
; 281(32): 22819-26, 2006 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16760475
9.
In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase.
J Pharmacol Exp Ther
; 317(1): 181-7, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368897
10.
The Hsp70 peptide-binding domain determines the interaction of the ATPase domain with Tim44 in mitochondria.
EMBO J
; 21(11): 2626-35, 2002 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-12032075