Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

A randomized, double-blind, placebo-controlled trial with mannan-conjugated birch pollen allergoids.

Mösges, Ralph; Zeyen, Christoph; Raskopf, Esther; Acikel, Cengizhan; Sahin, Hacer; Allekotte, Silke; Cuevas, Mandy; Shamji, Mohamed H; Subiza, José Luis; Casanovas, Miguel.

Allergy ; 79(4): 990-1000, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-37822222

2.

From trained immunity in allergy to trained immunity-based allergen vaccines.

Martín-Cruz, Leticia; Sevilla-Ortega, Carmen; Angelina, Alba; Domínguez-Andrés, Jorge; Netea, Mihai G; Subiza, José Luis; Palomares, Oscar.

Clin Exp Allergy ; 53(2): 145-155, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36494877

3.

Allergoid-mannan conjugates reprogram monocytes into tolerogenic dendritic cells via epigenetic and metabolic rewiring.

Benito-Villalvilla, Cristina; Pérez-Diego, Mario; Angelina, Alba; Kisand, Kai; Rebane, Ana; Subiza, José Luis; Palomares, Oscar.

J Allergy Clin Immunol ; 149(1): 212-222.e9, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34153371

4.

First-in-human phase 2 trial with mite allergoids coupled to mannan in subcutaneous and sublingual immunotherapy.

Nieto, Antonio; Mazón, Ángel; Nieto, María; Ibáñez, Ethel; Jang, Dah-Tay; Calaforra, Susana; Alba, Pilar; Pérez-Francés, Carmen; Llusar, Ruth; Montoro, Javier; de Mateo, Antonio; Alamar, Remedios; El-Qutob, David; Fernández, Javier; Moral, Luis; Toral, Teresa; Antón, Mónica; Andreu, Carmen; Ferrer, Ángel; Flores, Isabel-María; Cerdá, Neus; Del Pozo, Sandra; Caballero, Raquel; Subiza, José Luis; Casanovas, Miguel.

Allergy ; 77(10): 3096-3107, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35570712

5.

Bacterial Mucosal Immunotherapy with MV130 Prevents Recurrent Wheezing in Children: A Randomized, Double-Blind, Placebo-controlled Clinical Trial.

Nieto, Antonio; Mazón, Angel; Nieto, María; Calderón, Rafael; Calaforra, Susana; Selva, Blanca; Uixera, Sonia; Palao, Maria José; Brandi, Paola; Conejero, Laura; Saz-Leal, Paula; Fernández-Pérez, Cristina; Sancho, David; Subiza, José Luis; Casanovas, Miguel.

Am J Respir Crit Care Med ; 204(4): 462-472, 2021 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-33705665

6.

Prunus persica 9, a new occupational allergen from peach tree pollen involved in rhinitis and asthma.

Victorio-Puche, Laura; Somoza, Maria Luisa; Martin-Pedraza, Laura; Fernandez-Caldas, Enrique; Abel Fernandez, Eva; Moran, Mirian; Subiza, Jose Luis; Lopez-Sanchez, Jose Damian; Villalba, Mayte; Blanca, Miguel.

Occup Environ Med ; 78(2): 142-144, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33067336

7.

Alum impairs tolerogenic properties induced by allergoid-mannan conjugates inhibiting mTOR and metabolic reprogramming in human DCs.

Benito-Villalvilla, Cristina; Soria, Irene; Pérez-Diego, Mario; Fernández-Caldas, Enrique; Subiza, José Luis; Palomares, Oscar.

Allergy ; 75(3): 648-659, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31494959

8.

Human dendritic cells activated with MV130 induce Th1, Th17 and IL-10 responses via RIPK2 and MyD88 signalling pathways.

Cirauqui, Cristina; Benito-Villalvilla, Cristina; Sánchez-Ramón, Silvia; Sirvent, Sofía; Diez-Rivero, Carmen M; Conejero, Laura; Brandi, Paola; Hernández-Cillero, Lourdes; Ochoa, Juliana Lucía; Pérez-Villamil, Beatriz; Sancho, David; Subiza, José Luis; Palomares, Oscar.

Eur J Immunol ; 48(1): 180-193, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-28799230

9.

A pilot study of immunotherapy in dogs with atopic dermatitis using a mannan-Dermatophagoides farinae allergoid targeting dendritic cells.

González, José-Luis; Zalve, Vicente; Fernández-Caldas, Enrique; Cases, Bárbara; Subiza, José-Luis; Casanovas, Miguel.

Vet Dermatol ; 29(5): 449-e152, 2018 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-30183126

10.

Allergoid-mannan conjugates imprint tolerogenic features in human macrophages.

Benito-Villalvilla, Cristina; Pérez-Diego, Mario; Subiza, José Luis; Palomares, Oscar.

Allergy ; 77(1): 320-323, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34601743

11.

Allergens involved in the cross-reactivity of Aedes aegypti with other arthropods.

Cantillo, Jose Fernando; Puerta, Leonardo; Lafosse-Marin, Sylvie; Subiza, Jose Luis; Caraballo, Luis; Fernandez-Caldas, Enrique.

Ann Allergy Asthma Immunol ; 118(6): 710-718, 2017 06.

Artigo em Inglês | MEDLINE | ID: mdl-28434865

12.

Novel vaccines targeting dendritic cells by coupling allergoids to nonoxidized mannan enhance allergen uptake and induce functional regulatory T cells through programmed death ligand 1.

Sirvent, Sofía; Soria, Irene; Cirauqui, Cristina; Cases, Bárbara; Manzano, Ana I; Diez-Rivero, Carmen M; Reche, Pedro A; López-Relaño, Juan; Martínez-Naves, Eduardo; Cañada, F Javier; Jiménez-Barbero, Jesús; Subiza, Javier; Casanovas, Miguel; Fernández-Caldas, Enrique; Subiza, José Luis; Palomares, Oscar.

J Allergy Clin Immunol ; 138(2): 558-567.e11, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-27177779

13.

Identification and Characterization of IgE-Binding Tropomyosins in Aedes aegypti.

Cantillo, José Fernando; Puerta, Leonardo; Lafosse-Marin, Sylvie; Subiza, Jose Luis; Caraballo, Luis; Fernández-Caldas, Enrique.

Int Arch Allergy Immunol ; 170(1): 46-56, 2016.

Artigo em Inglês | MEDLINE | ID: mdl-27355916

14.

State of the Art in CAR-T Cell Therapy for Solid Tumors: Is There a Sweeter Future?

Amorós-Pérez, Beatriz; Rivas-Pardo, Benigno; Gómez Del Moral, Manuel; Subiza, José Luis; Martínez-Naves, Eduardo.

Cells ; 13(9)2024 Apr 23.

Artigo em Inglês | MEDLINE | ID: mdl-38727261

15.

MV130 in the Prevention of Recurrent Respiratory Tract Infections: A Retrospective Real-World Study in Children and Adults.

Montalbán-Hernández, Karla; Cogollo-García, Ana; Girón de Velasco-Sada, Patricia; Caballero, Raquel; Casanovas, Miguel; Subiza, José Luis; Conejero, Laura.

Vaccines (Basel) ; 12(2)2024 Feb 07.

Artigo em Inglês | MEDLINE | ID: mdl-38400155

16.

Reply.

Palomares, Oscar; Subiza, José Luis.

J Allergy Clin Immunol ; 139(4): 1405, 2017 04.

Artigo em Inglês | MEDLINE | ID: mdl-28088335

17.

A tumor-associated heparan sulfate-related glycosaminoglycan promotes the generation of functional regulatory T cells.

Martín-Cruz, Leticia; Viñuela, Marcos; Kalograiaki, Ioanna; Angelina, Alba; Oquist-Phillips, Paola; Real-Arévalo, Irene; Cañada, Francisco Javier; Tudela, José Ignacio; Moltó, Luis; Moreno-Sierra, Jesús; Subiza, José Luis; Palomares, Oscar.

Cell Mol Immunol ; 20(12): 1499-1512, 2023 12.

Artigo em Inglês | MEDLINE | ID: mdl-37990034

18.

Do bacterial vaccines/adjuvants prevent wheezing episodes in children?

Nieto, Antonio; Nieto, María; Conejero, Laura; Subiza, José Luis.

Curr Opin Allergy Clin Immunol ; 22(6): 380-386, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36305468

19.

Candida albicans V132 induces trained immunity and enhances the responses triggered by the polybacterial vaccine MV140 for genitourinary tract infections.

Martín-Cruz, Leticia; Angelina, Alba; Baydemir, Ilayda; Bulut, Özlem; Subiza, José Luis; Netea, Mihai G; Domínguez-Andrés, Jorge; Palomares, Oscar.

Front Immunol ; 13: 1066383, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36505433

20.

Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections.

Brandi, Paola; Conejero, Laura; Cueto, Francisco J; Martínez-Cano, Sarai; Dunphy, Gillian; Gómez, Manuel J; Relaño, Carlos; Saz-Leal, Paula; Enamorado, Michel; Quintas, Ana; Dopazo, Ana; Amores-Iniesta, Joaquín; Del Fresno, Carlos; Nistal-Villán, Estanislao; Ardavín, Carlos; Nieto, Antonio; Casanovas, Miguel; Subiza, José Luis; Sancho, David.

Cell Rep ; 38(1): 110184, 2022 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-34986349

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