Detalhe da pesquisa
1.
Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts.
PLoS Pathog
; 17(11): e1010069, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34748611
2.
Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to Mycobacterium tuberculosis infection.
J Antimicrob Chemother
; 77(4): 1061-1071, 2022 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084027
3.
Selective Anti-Leishmanial Strathclyde Minor Groove Binders Using an N-Oxide Tail-Group Modification.
Int J Mol Sci
; 23(19)2022 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36233213
4.
Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease.
Molecules
; 23(10)2018 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30336585
5.
Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy.
J Antimicrob Chemother
; 72(12): 3334-3341, 2017 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28961913
6.
Selective anti-malarial minor groove binders.
Bioorg Med Chem Lett
; 26(14): 3326-3329, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27212070
7.
An evaluation of Minor Groove Binders as anti-lung cancer therapeutics.
Bioorg Med Chem Lett
; 26(15): 3478-86, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27349332
8.
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1ß production via NRF2-mediated counter-regulation of the inflammasome.
J Autoimmun
; 60: 59-73, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25975491
9.
Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation.
Exp Parasitol
; 158: 18-22, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25836375
10.
Communication between the zinc and tetrahydrobiopterin binding sites in nitric oxide synthase.
Biochemistry
; 53(25): 4216-23, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24819538
11.
Recognition of the DNA minor groove by thiazotropsin analogues.
Chembiochem
; 15(13): 1978-90, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25045155
12.
The allure of targets for novel drugs.
RSC Med Chem
; 15(2): 472-484, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38389887
13.
MptpB Inhibitor Improves the Action of Antibiotics against Mycobacterium tuberculosis and Nontuberculous Mycobacterium avium Infections.
ACS Infect Dis
; 10(1): 170-183, 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38085851
14.
The diversity-oriented synthesis of pteridines - achievements and potential for development.
IUBMB Life
; 65(4): 283-99, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23440881
15.
Mechanistic exploration of the palladium-catalyzed process for the synthesis of benzoxazoles and benzothiazoles.
J Org Chem
; 78(4): 1471-7, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23316812
16.
Protection against lung pathology during obesity-accelerated ageing in mice by the parasitic worm product ES-62.
Front Immunol
; 14: 1285069, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38077318
17.
Multitargeted anti-infective drugs: resilience to resistance in the antimicrobial resistance era.
Future Drug Discov
; 4(1): FDD73, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35600289
18.
Ratiometric imaging of minor groove binders in mammalian cells using Raman microscopy.
RSC Chem Biol
; 3(12): 1403-1415, 2022 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36544571
19.
The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing.
Front Immunol
; 13: 953053, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36105811
20.
Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3.
ACS Infect Dis
; 8(12): 2552-2563, 2022 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36444998