Detalhe da pesquisa
1.
Clofazimine as a substitute for rifampicin improves efficacy of Mycobacterium avium pulmonary disease treatment in the hollow-fiber model.
Antimicrob Agents Chemother
; 68(3): e0115723, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38259101
2.
Drug interaction potential of high-dose rifampicin in patients with pulmonary tuberculosis.
Antimicrob Agents Chemother
; 67(10): e0068323, 2023 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37768317
3.
Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis.
Eur Respir J
; 61(3)2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36328357
4.
Relative bioavailability of delamanid 50 mg tablets dispersed in water in healthy adult volunteers.
Br J Clin Pharmacol
; 2023 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36692865
5.
New and Repurposed Drugs for the Treatment of Active Tuberculosis: An Update for Clinicians.
Respiration
; 102(2): 83-100, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36516792
6.
Early Bactericidal Activity of Meropenem plus Clavulanate (with or without Rifampin) for Tuberculosis: The COMRADE Randomized, Phase 2A Clinical Trial.
Am J Respir Crit Care Med
; 205(10): 1228-1235, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35258443
7.
Pharmacogenetics of Between-Individual Variability in Plasma Clearance of Bedaquiline and Clofazimine in South Africa.
J Infect Dis
; 226(1): 147-156, 2022 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35091749
8.
Optimizing Dosing and Fixed-Dose Combinations of Rifampicin, Isoniazid, and Pyrazinamide in Pediatric Patients With Tuberculosis: A Prospective Population Pharmacokinetic Study.
Clin Infect Dis
; 75(1): 141-151, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34665866
9.
Population Pharmacokinetic and Concentration-QTc Analysis of Delamanid in Pediatric Participants with Multidrug-Resistant Tuberculosis.
Antimicrob Agents Chemother
; 66(2): e0160821, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34843388
10.
Optimized Loading Dose Strategies for Bedaquiline When Restarting Interrupted Drug-Resistant Tuberculosis Treatment.
Antimicrob Agents Chemother
; 66(3): e0174921, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35007141
11.
Drug concentration at the site of disease in children with pulmonary tuberculosis.
J Antimicrob Chemother
; 77(6): 1710-1719, 2022 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35468189
12.
High-Dose Oral and Intravenous Rifampicin for the Treatment of Tuberculous Meningitis in Predominantly Human Immunodeficiency Virus (HIV)-Positive Ugandan Adults: A Phase II Open-Label Randomized Controlled Trial.
Clin Infect Dis
; 73(5): 876-884, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33693537
13.
An In Vitro Perspective on What Individual Antimicrobials Add to Mycobacterium avium Complex Therapies.
Antimicrob Agents Chemother
; 65(8): e0273020, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33972258
14.
Effect of Clofazimine Concentration on QT Prolongation in Patients Treated for Tuberculosis.
Antimicrob Agents Chemother
; 65(7): e0268720, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875426
15.
Relationship between Plasma and Intracellular Concentrations of Bedaquiline and Its M2 Metabolite in South African Patients with Rifampin-Resistant Tuberculosis.
Antimicrob Agents Chemother
; 65(11): e0239920, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34370588
16.
Increased bactericidal activity but dose-limiting intolerability at 50â mg·kg-1 rifampicin.
Eur Respir J
; 58(1)2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33542056
17.
Pharmacokinetics and safety of high-dose rifampicin in children with TB: the Opti-Rif trial.
J Antimicrob Chemother
; 76(12): 3237-3246, 2021 11 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34529779
18.
Constructing a representative in-silico population for paediatric simulations: Application to HIV-positive African children.
Br J Clin Pharmacol
; 87(7): 2847-2854, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33294979
19.
Normal fat mass cannot be reliably estimated in typical pharmacokinetic studies.
Eur J Clin Pharmacol
; 77(5): 727-733, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-33205282
20.
Rifampicin Can Be Given as Flat-Dosing Instead of Weight-Band Dosing.
Clin Infect Dis
; 71(12): 3055-3060, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31867594