Tumors of the esophagus, gastroesophageal junction, and stomach.

OBJECTIVES: To review the incidence, risk factors, staging, and diagnosis of esophageal, gastroesophageal junction, and stomach cancers, as well as nursing challenges associated with managing patients with these tumors. DATA SOURCES: Published research reports, epidemiologic data, published patient management guidelines, and institution-based clinical tools. CONCLUSION: While survival is slowly increasing, morbidity and mortality associated with upper gastrointestinal (UGI) cancers remain high. Research is needed to identify therapeutic approaches that will effectively decrease tumor burden and minimize physical consequences associated with disease and treatment. IMPLICATIONS FOR NURSING PRACTICE: Nurses need to be familiar with risk factors, disease course, and future therapies of UGI cancers to provide education relevant to preventive approaches, assist patients with treatment decision-making, and manage disease and treatment-induced sequela. Early identification and management of postoperative complications and nutritional issues can avoid life-threatening effects.

Quality of life after esophagectomy for cancer.

PURPOSE/OBJECTIVES: To examine symptoms and quality of life (QOL) of esophagectomy patients after curative surgery. DESIGN: Longitudinal, descriptive pilot study. SETTING: Comprehensive cancer center in the northeastern United States. SAMPLE: 23 patients were surveyed: 20 men and 3 women. The mean age was 62.3 years. METHODS: The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (version 2.0) and the esophageal-specific module were used. Data collection included three or four time points: before neoadjuvant treatment (if administered), before surgery, and three and six months after surgery. MAIN RESEARCH VARIABLES: The effects on symptoms and QOL of curative esophagectomy performed by a thoracic surgical oncologist. FINDINGS: Global QOL declined slightly over time; this change was not statistically significant. A significant inverse relationship was found between symptom intensity and global QOL. The intensity of hoarseness, reflux, and diarrhea increased significantly pre- to postsurgery. The average symptom intensity for the esophageal-specific subset of 24 symptoms increased significantly over time; the greatest intensity was found before surgery. CONCLUSIONS: Over the six-month observation period, the study found little average change in global QOL or functional status. However, symptoms increased significantly during this time period. Increased symptoms were associated with decreased QOL. IMPLICATIONS FOR NURSING: Symptom management should focus on symptoms that interfere with patients' QOL. Further research should target the evaluation of specific interventions for symptoms.