Detalhe da pesquisa
1.
Persistent ER stress causes GPI anchor deficit to convert a GPI-anchored prion protein into pro-PrP via the ATF6-miR449c-5p-PIGV axis.
J Biol Chem
; 299(8): 104982, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37390992
2.
Targeting type I collagen for cancer treatment.
Int J Cancer
; 151(5): 665-683, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35225360
3.
Melanoma migration is promoted by prion protein via Akt-hsp27 signaling axis.
Biochem Biophys Res Commun
; 523(2): 375-381, 2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31870551
4.
Prion dimer is heterogenous and is modulated by multiple negative and positive motifs.
Biochem Biophys Res Commun
; 509(2): 570-576, 2019 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30600179
5.
CD2-Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling.
Hepatology
; 68(5): 1710-1725, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29729186
6.
Prion protein is required for tumor necrosis factor α (TNFα)-triggered nuclear factor κB (NF-κB) signaling and cytokine production.
J Biol Chem
; 292(46): 18747-18759, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28900035
7.
Glycosylphosphatidylinositol Anchor Modification Machinery Deficiency Is Responsible for the Formation of Pro-Prion Protein (PrP) in BxPC-3 Protein and Increases Cancer Cell Motility.
J Biol Chem
; 291(8): 3905-17, 2016 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26683373
8.
Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1.
Am J Pathol
; 186(11): 2945-2956, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27639164
9.
Small protease sensitive oligomers of PrPSc in distinct human prions determine conversion rate of PrP(C).
PLoS Pathog
; 8(8): e1002835, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22876179
10.
Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate.
PLoS Pathog
; 7(9): e1002242, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21931554
11.
Glycosylphosphatidylinositol anchor modification machinery deficiency is responsible for the formation of pro-prion protein (PrP) in BxPC-3 cells and increases cancer cell motility.
J Biol Chem
; 291(13): 6785, 2016 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27016554
12.
GPI-anchored ligand-BioID2-tagging system identifies Galectin-1 mediating Zika virus entry.
iScience
; 25(12): 105481, 2022 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36404916
13.
Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.
Cell Rep
; 41(12): 111834, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36543142
14.
Pro-prion binds filamin A, facilitating its interaction with integrin beta1, and contributes to melanomagenesis.
J Biol Chem
; 285(39): 30328-39, 2010 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20650901
15.
PrP conformational transitions alter species preference of a PrP-specific antibody.
J Biol Chem
; 285(18): 13874-84, 2010 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-20194495
16.
A multistage pathway for human prion protein aggregation in vitro: from multimeric seeds to ß-oligomers and nonfibrillar structures.
J Am Chem Soc
; 133(22): 8586-93, 2011 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21534611
17.
Tumor Necrosis Factor α Reduces SNAP29 Dependent Autolysosome Formation to Increase Prion Protein Level and Promote Tumor Cell Migration.
Virol Sin
; 36(3): 458-475, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33237393
18.
Crizotinib and Doxorubicin Cooperatively Reduces Drug Resistance by Mitigating MDR1 to Increase Hepatocellular Carcinoma Cells Death.
Front Oncol
; 11: 650052, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34094940
19.
Role of the highly conserved middle region of prion protein (PrP) in PrP-lipid interaction.
Biochemistry
; 49(37): 8169-76, 2010 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20718504
20.
Residues at P2-P1 positions of epsilon- and zeta-cleavage sites are important in formation of beta-amyloid peptide.
Neurobiol Dis
; 36(3): 453-60, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19716417