Detalhe da pesquisa
1.
How autoreactive thymocytes differentiate into regulatory versus effector CD4+ T cells after avoiding clonal deletion.
Nat Immunol
; 24(4): 637-651, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36959291
2.
Identification of lineage-specifying cytokines that signal all CD8+-cytotoxic-lineage-fate 'decisions' in the thymus.
Nat Immunol
; 18(11): 1218-1227, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28945245
3.
Timing and duration of MHC I positive selection signals are adjusted in the thymus to prevent lineage errors.
Nat Immunol
; 17(12): 1415-1423, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27668801
4.
Lck availability during thymic selection determines the recognition specificity of the T cell repertoire.
Cell
; 154(6): 1326-41, 2013 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24034254
5.
IL-7 signaling must be intermittent, not continuous, during CD8⺠T cell homeostasis to promote cell survival instead of cell death.
Nat Immunol
; 14(2): 143-51, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23242416
6.
Clonal deletion and the fate of autoreactive thymocytes that survive negative selection.
Nat Immunol
; 13(6): 569-78, 2012 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22544394
7.
Activated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammation.
Immunity
; 40(6): 910-23, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24909888
8.
Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals.
Immunity
; 38(6): 1116-28, 2013 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23746651
9.
Coreceptor gene imprinting governs thymocyte lineage fate.
EMBO J
; 31(2): 366-77, 2012 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22036949
10.
CD28-CD80/86 and CD40-CD40L Interactions Promote Thymic Tolerance by Regulating Medullary Epithelial Cell and Thymocyte Development.
Crit Rev Immunol
; 35(1): 59-76, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25746048
11.
Regulation of MHC class I expression by Foxp3 and its effect on regulatory T cell function.
J Immunol
; 192(6): 2892-903, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24523508
12.
Pim1 permits generation and survival of CD4+ T cells in the absence of γc cytokine receptor signaling.
Eur J Immunol
; 43(9): 2283-94, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23712827
13.
MCL-1 keeps a charming home for thymocytes.
Blood
; 130(23): 2448-2450, 2017 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29217698
14.
Basis of CTLA-4 function in regulatory and conventional CD4(+) T cells.
Blood
; 119(22): 5155-63, 2012 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22403258
15.
CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways.
Int Immunol
; 25(12): 671-81, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24048955
16.
An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis.
J Immunol
; 188(12): 5859-66, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22593613
17.
CD8 T cell tolerance results from eviction of immature autoreactive cells from the thymus.
Science
; 382(6670): 534-541, 2023 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37917689
18.
The small intestine epithelium exempts Foxp3+ Tregs from their IL-2 requirement for homeostasis and effector function.
JCI Insight
; 6(21)2021 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34747370
19.
The Cytokine Receptor IL-7Rα Impairs IL-2 Receptor Signaling and Constrains the In Vitro Differentiation of Foxp3+ Treg Cells.
iScience
; 23(8): 101421, 2020 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32791329
20.
Novel MHC-Independent αßTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus.
Front Immunol
; 11: 1216, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32612609