Detalhe da pesquisa
1.
Allelic series of Huntington's disease knock-in mice reveals expression discorrelates.
Hum Mol Genet
; 25(8): 1619-36, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908599
2.
Differential effects of delayed aging on phenotype and striatal pathology in a murine model of Huntington disease.
J Neurosci
; 34(47): 15658-68, 2014 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25411494
3.
Differential recruitment of UBQLN2 to nuclear inclusions in the polyglutamine diseases HD and SCA3.
Neurobiol Dis
; 82: 281-288, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26141599
4.
Mitochondrial calcium uptake capacity as a therapeutic target in the R6/2 mouse model of Huntington's disease.
Hum Mol Genet
; 19(17): 3354-71, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20558522
5.
Early autophagic response in a novel knock-in model of Huntington disease.
Hum Mol Genet
; 19(19): 3702-20, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20616151
6.
Evaluation of tetrathiomolybdate in the R6/2 model of Huntington disease.
Neurosci Lett
; 452(1): 60-2, 2009 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19429000
7.
Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease.
J Neurosci
; 27(34): 8989-98, 2007 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17715336
8.
Hprt(CAG)146 mice: age of onset of behavioral abnormalities, time course of neuronal intranuclear inclusion accumulation, neurotransmitter marker alterations, mitochondrial function markers, and susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
J Comp Neurol
; 465(2): 205-19, 2003 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-12949782
9.
The de-ubiquitinating enzyme ataxin-3 does not modulate disease progression in a knock-in mouse model of Huntington disease.
J Huntingtons Dis
; 2(2): 201-15, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24683430
10.
Lack of efficacy of NMDA receptor-NR2B selective antagonists in the R6/2 model of Huntington disease.
Exp Neurol
; 225(2): 402-7, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20659453
11.
Treating mouse models of Huntington disease.
Neuropsychopharmacology
; 36(12): 2373-4, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21814186
12.
Nucleocytoplasmic transport signals affect the age at onset of abnormalities in knock-in mice expressing polyglutamine within an ectopic protein context.
Hum Mol Genet
; 12(13): 1621-9, 2003 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12812988