Detalhe da pesquisa
1.
Kv1.3 blockade by ShK186 modulates CD4+ effector memory T-cell activity of patients with granulomatosis with polyangiitis.
Rheumatology (Oxford)
; 63(1): 198-208, 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37086441
2.
Safety and Pharmacokinetics of LHF-535, a Potential Treatment for Lassa Fever, in Healthy Adults.
Antimicrob Agents Chemother
; 66(11): e0095122, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36314868
3.
Durable pharmacological responses from the peptide ShK-186, a specific Kv1.3 channel inhibitor that suppresses T cell mediators of autoimmune disease.
J Pharmacol Exp Ther
; 342(3): 642-53, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22637724
4.
Lassa antiviral LHF-535 protects guinea pigs from lethal challenge.
Sci Rep
; 12(1): 19911, 2022 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36402782
5.
Kv1.3 Channel Blockade Modulates the Effector Function of B Cells in Granulomatosis with Polyangiitis.
Front Immunol
; 8: 1205, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29018452
6.
Safety and pharmacodynamics of dalazatide, a Kv1.3 channel inhibitor, in the treatment of plaque psoriasis: A randomized phase 1b trial.
PLoS One
; 12(7): e0180762, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28723914
7.
Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases.
Toxicon
; 59(4): 529-46, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21867724
8.
Evolution of the mating type locus: insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii.
Eukaryot Cell
; 6(4): 622-9, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17337636
9.
A recombinant aspartyl protease of Coccidioides posadasii induces protection against pulmonary coccidioidomycosis in mice.
Infect Immun
; 74(1): 516-27, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16369008
10.
Multivalent recombinant protein vaccine against coccidioidomycosis.
Infect Immun
; 74(10): 5802-13, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16988258