RESUMO
Available data on the effect of various trace elements on iodine metabolism and function of thyroid gland (TG) were systematized in this article. Subsequently, promising possibilities of herbal therapy in treatment and prevention of TG diseases were considered. Systemic analyis of the results of 3 independent open-label clinical studies performed in accordance with requirements of evidence-based medicine that involved herbal medicinal product Alba® (root extract of white cinquefoil) was carried out. Therapeutic options of Alba® use in various TG pathologies were presented.
Assuntos
Fitoterapia , Preparações de Plantas/uso terapêutico , Potentilla/química , Doenças da Glândula Tireoide/tratamento farmacológico , Humanos , Preparações de Plantas/administração & dosagem , Preparações de Plantas/isolamento & purificação , Ensaios Clínicos Controlados Aleatórios como Assunto , Doenças da Glândula Tireoide/etiologia , Doenças da Glândula Tireoide/metabolismo , Doenças da Glândula Tireoide/prevenção & controle , Hormônios Tireóideos/metabolismo , Resultado do TratamentoRESUMO
High prevalence of hyperplastic and autoimmune diseases of thyroid in Ukrainian population is determined by endemic deficit of iodine and selenium. The aim of this research was to assess the place of biologically-active additions on the basis of herbal material containing an iodine and selenium in prophylaxis and treatment of thyroid pathology. During the six month period 55 patients received herbal preparation Alba twice a day. The levels of TSH, volume of thyroid, the sizes of nodular goiter (ultrasound investigation) were measured before and at the end of the investigation. The levels of thyroid stimulating antibodies to TSH receptor (AB-r TSH) were evaluated in patients with hyperthyroidism. The results of Alba application showed that in patients with thyroid pathology (diffuse nontoxic goiter, hyperthyroidism and chronic thyroiditis) it was possible to reduce the volume of thyroid, normalize its function, and decrease the level of AB-r TSH in diffuse toxic goiter. We also found approximately 20 % shortening of the time needed to get target level of TSH and finally the duration of treatment of thyrotoxicosis.