Detalhe da pesquisa
1.
Structural Dynamics of Amyloid-ß Protofibrils and Actions of Anti-Amyloid-ß Antibodies as Observed by High-Speed Atomic Force Microscopy.
Nano Lett
; 23(13): 6259-6268, 2023 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37141711
2.
From reaction kinetics to dementia: A simple dimer model of Alzheimer's disease etiology.
PLoS Comput Biol
; 17(7): e1009114, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34280181
3.
Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease.
Brain
; 143(1): 336-358, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794021
4.
High molecular weight amyloid ß1-42 oligomers induce neurotoxicity via plasma membrane damage.
FASEB J
; 33(8): 9220-9234, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31084283
5.
High-speed atomic force microscopy reveals structural dynamics of amyloid ß1-42 aggregates.
Proc Natl Acad Sci U S A
; 113(21): 5835-40, 2016 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27162352
6.
A novel role for osteopontin in macrophage-mediated amyloid-ß clearance in Alzheimer's models.
Brain Behav Immun
; 67: 163-180, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28860067
7.
Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-ß assembly.
Proc Natl Acad Sci U S A
; 112(32): E4465-74, 2015 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26224839
8.
A Critical Role of Ser26 Hydrogen Bonding in Aß42 Assembly and Toxicity.
Biochemistry
; 56(48): 6321-6324, 2017 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29140083
9.
Pittsburgh Compound-B (PiB) binds amyloid ß-protein protofibrils.
J Neurochem
; 140(2): 210-215, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27943341
10.
Synaptic Amyloid-ß Oligomers Precede p-Tau and Differentiate High Pathology Control Cases.
Am J Pathol
; 186(1): 185-98, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26718979
11.
Preparation of pure populations of covalently stabilized amyloid ß-protein oligomers of specific sizes.
Anal Biochem
; 518: 78-85, 2017 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27810329
12.
Design, Characterization, and Use of a Novel Amyloid ß-Protein Control for Assembly, Neurotoxicity, and Gene Expression Studies.
Biochemistry
; 55(36): 5049-60, 2016 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-27505174
13.
Amyloid ß-Protein Assembly and Alzheimer's Disease: Dodecamers of Aß42, but Not of Aß40, Seed Fibril Formation.
J Am Chem Soc
; 138(6): 1772-5, 2016 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26839237
14.
Amyloid ß-Protein C-Terminal Fragments: Formation of Cylindrins and ß-Barrels.
J Am Chem Soc
; 138(2): 549-57, 2016 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26700445
15.
Design and Characterization of Chemically Stabilized Aß42 Oligomers.
Biochemistry
; 54(34): 5315-21, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26241378
16.
Inhibiting amyloid ß-protein assembly: Size-activity relationships among grape seed-derived polyphenols.
J Neurochem
; 135(2): 416-30, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26228682
17.
Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment.
J Neurosci
; 32(15): 5144-50, 2012 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22496560
18.
Phenolic compounds prevent amyloid ß-protein oligomerization and synaptic dysfunction by site-specific binding.
J Biol Chem
; 287(18): 14631-43, 2012 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22393064
19.
A gamma-secretase-like intramembrane cleavage of TNFalpha by the GxGD aspartyl protease SPPL2b.
Nat Cell Biol
; 8(8): 894-6, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16829951
20.
Extracellular high molecular weight α-synuclein oligomers induce cell death by disrupting the plasma membrane.
NPJ Parkinsons Dis
; 9(1): 139, 2023 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37770475